IAP
IAP (Inhibitor of Apoptosis Protein) inhibitors are compounds that block the activity of IAPs, a family of proteins that prevent apoptosis by inhibiting caspases and other components of the apoptotic machinery. IAP inhibitors promote apoptosis in cancer cells by neutralizing these survival signals, making them important tools in cancer research and therapy. At CymitQuimica, we offer a comprehensive range of high-quality IAP inhibitors to support your research in oncology, apoptosis, and therapeutic development.
Found 71 products for "IAP".
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MV1
CAS:MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.Formula:C33H44N4O5Purity:99.86%Color and Shape:SolidMolecular weight:576.73Ref: TM-T16163
2mg44.00€5mg67.00€1mL*10mM (DMSO)86.00€10mg112.00€25mg187.00€50mg280.00€100mg396.00€200mg522.00€XIAP BIR2/BIR2-3 inhibitor-2
CAS:XIAP BIR2/BIR2-3 Inhibitor-2 is a dual inhibitor of BIR2 and BIR2-3 with IC50 values less than 1 nM. It can be used in the study of cancers [1].Formula:C80H96N20O12Molecular weight:1529.75S2/IAPinh
S2/IAPinh is a conjugate composed of an inhibitor of apoptosis proteins inhibitor (IAPinh) and a ligand of sigma 2 SW43. It demonstrates anti-proliferative and apoptosis-inducing activity by degrading inhibitor of apoptosis proteins (clAP-1).Formula:C52H75Cl2FN6O6SColor and Shape:SolidMolecular weight:1000.48299XIAP BIR2/BIR2-3 inhibitor-3
CAS:XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].Formula:C86H106N18O16S2Color and Shape:SolidMolecular weight:1712XIAP BIR2/BIR2-3 inhibitor-1
CAS:XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) serves as a potent dual inhibitor targeting BIR2 and BIR2-3 domains, with IC50 values of 1.9 nM and 0.8 nM, respectively. This compound is utilized in cancer research studies [1].Formula:C72H96N16O14Color and Shape:SolidMolecular weight:1409.63SBP-0636457
CAS:SBP-0636457: SMAC mimetic, IAP inhibitor, binds BIR-domains (Ki=0.27μM), potential in tumor/cancer research.Formula:C25H36N4O4Color and Shape:SolidMolecular weight:456.587SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.Formula:C62H85ClN14O6Purity:98%Color and Shape:SolidMolecular weight:1157.88Dasminapant
CAS:APG-1387 inhibits IAPs, degrades cIAP1/2, XIAP, boosts chemosensitivity, and induces apoptosis in NPC.Formula:C60H72N10O10S2Color and Shape:White SolidMolecular weight:1157.41PROTAC KRAS G12C degrader-2
CAS:PROTAC KRAS G12C degrader-2 (compound 432) is a targeted modulator of K-Ras protein hydrolysis that functions as a bifunctional PROTAC molecule, incorporating a cereblon inhibitor of apoptosis proteins (IAP) ligand on one terminus and a KRAS-binding moiety on the opposite end, thereby enabling selective recruitment of mutant KRAS G12C to the ubiquitin–proteasome system for controlled degradation and mechanistic investigation of KRAS-driven oncogenic signaling pathways.Formula:C51H53ClFN9O7Color and Shape:SolidMolecular weight:958.47MDM2/XIAP-IN-1
MDM2/XIAP-IN-1 (compound 14) is an orally active dual inhibitor of MDM2 and XIAP, exhibiting anti-cancer activity with an IC50 of 0.3 μM and potentialColor and Shape:Odour SolidCST626
CAS:CST626 is a PROTAC degrader that targets XIAP, cIAP1, and cIAP2.Formula:C61H82N8O9SPurity:95.87%Color and Shape:SolidMolecular weight:1103.42Anti-CD47 Antibody (4E249)
Anti-CD47 Antibody (4E249) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (4E249) can be used in ELISA.Color and Shape:Odour LiquidAnti-CD47 Antibody (5R542)
Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.Color and Shape:Odour LiquidAnti-CD47 Antibody (5K435)
Anti-CD47 Antibody (5K435) is an antibody targeting CD47. Anti-CD47 Antibody (5K435) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidCD47 Protein, Mouse, Recombinant (rFc)
CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag.Color and Shape:Lyophilized PowderMolecular weight:39.9 kDa (predicted)Anti-CD47 Antibody (5S892)
Anti-CD47 Antibody (5S892) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5S892) can be used in IHC-P.Color and Shape:Odour LiquidAnti-CD47 Antibody (9X161)
Anti-CD47 Antibody (9X161) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (9X161) can be used in FCM.Color and Shape:Odour LiquidAnti-CD47 Antibody-FITC (9X161)
Anti-CD47 Antibody-FITC (9X161) is a FITC-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-FITC (9X161) can be used in FCM.Color and Shape:Odour LiquidAnti-CD47 Antibody (4C168)
Anti-CD47 Antibody (4C168) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (4C168) can be used in IHC-P.Color and Shape:Odour LiquidAnti-CD47 Antibody (6T428)
Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.Color and Shape:Odour LiquidAnti-CD47 Antibody (5E321)
Anti-CD47 Antibody (5E321) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (5E321) can be used in ELISA.Color and Shape:Odour LiquidAnti-CD47 Antibody (1F304)
Anti-CD47 Antibody (1F304) is an antibody targeting CD47. Anti-CD47 Antibody (1F304) can be used in ELISA, FCM.Color and Shape:Odour LiquidAnti-CD47 Antibody (8A121)
Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.Color and Shape:Odour LiquidAnti-CD47 Antibody-PE (9X161)
Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.Color and Shape:Odour LiquidAnti-CD47 Antibody (8K78)
Anti-CD47 Antibody (8K78) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (8K78) can be used in WB,ELISA,IP.Color and Shape:Odour LiquidAZD5582
CAS:AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.Formula:C58H78N8O8Purity:98.75% - >99.99%Color and Shape:SolidMolecular weight:1015.29CD47 Protein, Mouse, Recombinant (His)
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:SDS-PAGE: 98.3%; SEC-HPLC: 98.5%Color and Shape:Lyophilized PowderMolecular weight:15.3 kDa (predicted); 34-44 kDa (reducing condition, due to glycosylation)Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and isPurity:92.7%Color and Shape:Lyophilized PowderMolecular weight:54.1 kDa (predicted); 66 kDa (reducing conditions)Ref: TM-TMPY-00570
5µg78.00€10µg110.00€20µg177.00€50µg348.00€100µg613.00€200µg1,080.00€500µg2,277.00€CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag.Color and Shape:White Lyophilized PowderMolecular weight:30-40 KDa (reducing condition)CD47 Protein, Human, Recombinant (hFc)
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCColor and Shape:White Lyophilized PowderMolecular weight:40.5 kDa (predicted); 55-65 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.Color and Shape:Lyophilized PowderMolecular weight:48-65 KDa (reducing condition)Ref: TM-TMPJ-00212
5µg56.00€10µg88.00€20µg118.00€50µg200.00€100µg358.00€200µg643.00€500µg1,414.00€1mg2,457.00€CD47 Protein, Human, Recombinant (aa 19-139, His)
CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted); 40-55 kDa (reducing conditions)Ref: TM-TMPY-06367
5µg77.00€10µg112.00€20µg177.00€50µg351.00€100µg680.00€200µg1,018.00€500µg2,152.00€1mg4,393.00€Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalColor and Shape:Lyophilized PowderMolecular weight:54.5 kDa (predicted). Due to glycosylation, the protein migrates to 63-73 kDa based on Tris-Bis PAGE result.Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalColor and Shape:Lyophilized PowderMolecular weight:53.10 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Color and Shape:Lyophilized PowderMolecular weight:17.1 kDa (predicted); 38.8 kDa (reducing conditions)Alkaline phosphatase/ALPI Protein, Human, Recombinant (hFc)
Alkaline phosphatase Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:79.5 kDa (predicted); 90-95 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (aa 1-139, His)
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag.Purity:SDS-PAGE: 98.4%; SEC-HPLC: 97.6%Color and Shape:Lyophilized PowderMolecular weight:15.2 kDa (predicted); 35-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (His)
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Purity:Greater than 95% as determined by reducing SDS-PAGE. - SDS-PAGE: 100%; SEC-HPLC: 97%Color and Shape:White Lyophilized PowderMolecular weight:30-45 KDa (reducing condition)CD47 Protein, Human, Recombinant, Biotinylated
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells.Purity:97.6%Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted)CD47 Protein, Mouse, Recombinant
CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.Color and Shape:Lyophilized PowderMolecular weight:13.8 kDa (predicted)CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.Color and Shape:Lyophilized PowderMolecular weight:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:White Lyophilized PowderMolecular weight:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.Purity:97.8%Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase/ALPI Protein, Human, Recombinant (His)
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:98.4%Color and Shape:White Lyophilized PowderMolecular weight:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formula:C30H42FN5O3Purity:98.33% - 99.85%Color and Shape:White SolidMolecular weight:539.68Ref: TM-TQ0029
1mg79.00€5mg137.00€1mL*10mM (DMSO)163.00€10mg205.00€25mg409.00€50mg605.00€100mg860.00€Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormula:C57H92O27Purity:98.95% - ≥98%Color and Shape:SolidMolecular weight:1209.4GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Formula:C25H34N6O3SPurity:97.18% - 99.32%Color and Shape:SolidMolecular weight:498.64Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFormula:C42H56F2N8O6Purity:97.08% - ≥95%Color and Shape:SolidMolecular weight:806.94Ref: TM-T6007
1mg34.00€2mg46.00€5mg70.00€1mL*10mM (DMSO)92.00€10mg109.00€25mg172.00€50mg250.00€100mg447.00€4-Methylsalicylic acid
CAS:4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Formula:C8H8O3Purity:99.64%Color and Shape:White SolidMolecular weight:152.15SM-164
CAS:SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Formula:C62H84N14O6Purity:98.53% - 99.92%Color and Shape:SolidMolecular weight:1121.42
