CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Found 546 products of "CDK"
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FIT-039
CAS:FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).Formula:C17H18FN3SPurity:98.61%Color and Shape:SolidMolecular weight:315.41THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Formula:C31H28ClN7O2Purity:97.42% - 99.27%Color and Shape:SolidMolecular weight:566.05SB1317 hydrochloride (1204918-72-8(free base))
SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).Formula:C23H25ClN4OPurity:99.84%Color and Shape:SolidMolecular weight:408.92Ref: TM-T4227
1mg50.00€2mg65.00€5mg107.00€10mg170.00€25mg306.00€50mg371.00€100mg553.00€1mL*10mM (DMSO)117.00€Ro-3306
CAS:RO-3306: ATP-competitive CDK1 inhibitor, Ki 20 nM, >15x more selective than other human kinases.Formula:C18H13N3OS2Purity:97.67% - 99.79%Color and Shape:SolidMolecular weight:351.45PF-562271
CAS:PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).Formula:C21H20F3N7O3SPurity:97.17% - >99.99%Color and Shape:SolidMolecular weight:507.49AZD-5438
CAS:AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Formula:C18H21N5O2SPurity:99.73% - 99.87%Color and Shape:SolidMolecular weight:371.46PHA-767491
CAS:PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.Formula:C12H11N3OPurity:99.49% - >99.99%Color and Shape:SolidMolecular weight:213.24Ref: TM-T6206
2mg34.00€5mg49.00€10mg64.00€25mg92.00€50mg138.00€100mg197.00€200mg295.00€1mL*10mM (DMSO)50.00€NVP-LCQ195
CAS:NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Formula:C17H19Cl2N5O4SPurity:99.56% - 99.85%Color and Shape:SolidMolecular weight:460.33Ref: TM-TQ0068
1mg46.00€5mg92.00€10mg138.00€25mg255.00€50mg374.00€100mg533.00€200mg705.00€1mL*10mM (DMSO)94.00€PHA-767491 hydrochloride
CAS:PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.Formula:C12H12ClN3OPurity:99.56% - 99.92%Color and Shape:SolidMolecular weight:249.69Roniciclib
CAS:Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.Formula:C18H21F3N4O3SPurity:98% - 98.63%Color and Shape:SolidMolecular weight:430.44P18IN011
CAS:P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
Formula:C15H12N2O5SPurity:97.63%Color and Shape:SolidMolecular weight:332.33SNS-032
CAS:SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over CDK1/CDK4. SNS-032 is sensitive to CDK7/9, and no effect on CDK6.Formula:C17H24N4O2S2Purity:98.27% - 99.91%Color and Shape:SolidMolecular weight:380.53Ref: TM-T6049
5mg48.00€10mg63.00€25mg92.00€50mg124.00€100mg202.00€200mg299.00€500mg504.00€1mL*10mM (DMSO)50.00€THAL-SNS-032
CAS:THAL-SNS-032 is a selective CDK9 degrader PROTAC.Formula:C40H52N8O10S2Purity:99.68%Color and Shape:SolidMolecular weight:869.02Ref: TM-T17069
1mg110.00€5mg259.00€10mg389.00€25mg622.00€50mg884.00€100mg1,198.00€1mL*10mM (DMSO)389.00€LDC000067
CAS:LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.Formula:C18H18N4O3SPurity:98.08% - 99.07%Color and Shape:SolidMolecular weight:370.43LY3405105
CAS:LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-Formula:C26H39N7O3Purity:99.66%Color and Shape:SolidMolecular weight:497.63ON-013100
CAS:ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.Formula:C19H22O7SPurity:98.27%Color and Shape:SolidMolecular weight:394.44Ref: TM-T16391
1mg48.00€5mg71.00€10mg100.00€25mg172.00€50mg268.00€100mg404.00€200mg570.00€1mL*10mM (DMSO)60.00€SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFormula:C15H19Br2ClN4Purity:98.13% - 98.47%Color and Shape:SolidMolecular weight:450.6Trilaciclib
CAS:Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.Formula:C24H30N8OPurity:99.624%Color and Shape:SolidMolecular weight:446.55Purvalanol A
CAS:Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.Formula:C19H25ClN6OPurity:98.13% - 99.68%Color and Shape:PowderMolecular weight:388.89TP-353
CAS:TP-353 (EOS-61973) is a CDK7 inhibitor.Formula:C35H30FNO3Purity:99.12%Color and Shape:SolidMolecular weight:531.62Ref: TM-T22440
1mg43.00€5mg80.00€10mg129.00€25mg225.00€50mg314.00€100mg432.00€200mg597.00€1mL*10mM (DMSO)105.00€(E/Z)-TG003
CAS:(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.Formula:C13H15NO2SPurity:98% - 99.04%Color and Shape:SolidMolecular weight:249.33Ref: TM-T1901
2mg42.00€5mg52.00€10mg92.00€25mg164.00€50mg271.00€100mg399.00€200mg567.00€1mL*10mM (DMSO)52.00€Atuveciclib
CAS:Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.Formula:C18H18FN5O2SPurity:98.8%Color and Shape:SolidMolecular weight:387.43Ref: TM-T10464L
1mg84.00€2mg114.00€5mg192.00€10mg313.00€25mg580.00€50mg773.00€100mg1,063.00€1mL*10mM (DMSO)212.00€Palbociclib
CAS:Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.Formula:C24H29N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:447.53Dalpiciclib
CAS:Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.
Formula:C25H30N6O2Purity:99.69%Color and Shape:SolidMolecular weight:446.54Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFormula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24Amantadine
CAS:Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.
Formula:C10H17NPurity:99.73% - 99.94%Color and Shape:Hexakistetrahedral Crystals By Sublimation SolidMolecular weight:151.25Senexin B
CAS:Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).Formula:C27H26N6OPurity:99.67%Color and Shape:SolidMolecular weight:450.53Ref: TM-T8430
1mg92.00€5mg178.00€10mg260.00€25mg401.00€50mg532.00€100mg708.00€200mg964.00€1mL*10mM (DMSO)203.00€AT7519
CAS:AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.Formula:C16H17Cl2N5O2Purity:98.88% - 99.65%Color and Shape:SolidMolecular weight:382.24NSC23005
CAS:NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).Formula:C13H17NO4SPurity:>99.99%Color and Shape:SolidMolecular weight:283.34SRI-29329
CAS:SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).Formula:C20H26ClN7Purity:99.18%Color and Shape:SolidMolecular weight:399.92BGG463
CAS:BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 μM, 0.09 μM and 0.590 μM, respectively.Formula:C30H29F3N6O3Purity:98.21% - >99.99%Color and Shape:SolidMolecular weight:578.58Ref: TM-T4618
1mg58.00€2mg82.00€5mg113.00€10mg178.00€25mg333.00€50mg477.00€100mg692.00€1mL*10mM (DMSO)145.00€Indirubin-3′-oxime
CAS:Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.Formula:C16H11N3O2Purity:98.34%Color and Shape:SolidMolecular weight:277.28Ref: TM-T9138
1mg44.00€5mg93.00€10mg120.00€25mg236.00€50mg356.00€100mg532.00€200mg772.00€1mL*10mM (DMSO)92.00€BI-1347
CAS:BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Formula:C22H20N4OPurity:96.7% - 99.63%Color and Shape:SolidMolecular weight:356.42Ref: TM-T5405
1mg40.00€5mg88.00€10mg126.00€25mg240.00€50mg439.00€100mg647.00€500mg1,359.00€1mL*10mM (DMSO)87.00€Aminopurvalanol A
CAS:Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1Formula:C19H26ClN7OPurity:99.73%Color and Shape:SolidMolecular weight:403.91Ref: TM-T22260
2mg39.00€5mg60.00€10mg92.00€25mg173.00€50mg269.00€100mg389.00€200mg555.00€1mL*10mM (DMSO)62.00€YKL-5-124
CAS:YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displaysFormula:C28H33N7O3Purity:99.36%Color and Shape:SolidMolecular weight:515.61Ref: TM-T22461
1mg96.00€2mg135.00€5mg188.00€10mg341.00€25mg548.00€50mg782.00€100mg1,035.00€1mL*10mM (DMSO)225.00€BS-181 dihydrochloride
CAS:BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.Formula:C22H34Cl2N6Color and Shape:SolidMolecular weight:453.46MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg34.00€5mg50.00€10mg86.00€25mg161.00€50mg245.00€100mg363.00€200mg515.00€1mL*10mM (DMSO)55.00€1-NM-PP1
CAS:1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.Formula:C20H21N5Purity:98% - 98.93%Color and Shape:White Cyrstalline SolidMolecular weight:331.41Ref: TM-T2153
1mg48.00€2mg63.00€5mg84.00€10mg132.00€25mg271.00€50mg505.00€100mg668.00€1mL*10mM (DMSO)90.00€SU9516
CAS:SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formula:C13H11N3O2Purity:99.34% - 99.96%Color and Shape:SolidMolecular weight:241.25Ref: TM-T6167
1mg35.00€2mg50.00€5mg73.00€10mg103.00€25mg208.00€50mg376.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)74.00€Palbociclib Isethionate
CAS:Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。
Formula:C24H29N7O2·C2H6O4SPurity:99.01% - 99.27%Color and Shape:SolidMolecular weight:573.66Wogonin
CAS:Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.Formula:C16H12O5Purity:98% - 99.8%Color and Shape:Yellow CrystalMolecular weight:284.26Ref: TM-T2933
5mg34.00€10mg42.00€25mg59.00€50mg92.00€100mg131.00€200mg178.00€500mgTo inquire1mL*10mM (DMSO)52.00€Toyocamycin
CAS:Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (Formula:C12H13N5O4Purity:98.1% - 99.44%Color and Shape:SolidMolecular weight:291.26Ref: TM-T17143
5mg44.00€10mg62.00€25mg107.00€50mg192.00€100mg334.00€500mg782.00€1mL*10mM (DMSO)48.00€Palbociclib monohydrochloride
CAS:Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases
Formula:C24H29N7O2·HClPurity:99.73% - >99.99%Color and Shape:SolidMolecular weight:483.99Purvalanol B
CAS:Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formula:C20H25ClN6O3Purity:98.95%Color and Shape:SolidMolecular weight:432.9Ref: TM-T7167
1mg34.00€2mg46.00€5mg67.00€10mg90.00€25mg130.00€50mg203.00€100mg305.00€200mg447.00€1mL*10mM (DMSO)75.00€TC11
CAS:TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosisFormula:C20H22N2O2Purity:97.86%Color and Shape:SolidMolecular weight:322.4PNU112455A hydrochloride
CAS:PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.Formula:C10H12ClN5O2SPurity:98.58% - 99.22%Color and Shape:SolidMolecular weight:301.75Ref: TM-T8230
2mg44.00€5mg71.00€10mg100.00€25mg172.00€50mg266.00€100mg434.00€500mg964.00€1mL*10mM (DMSO)79.00€LDC4297 hydrochloride
CAS:LDC4297 hydrochloride is a selective and potent CDK7 inhibitor with broad-spectrum antiviral activity, useful for research on viral infections.Formula:C23H29ClN8OColor and Shape:SolidMolecular weight:468.98CDK9-IN-30
CAS:CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.Formula:C16H20FNO3Purity:99.75%Color and Shape:SolidMolecular weight:293.33Ref: TM-T9632
1mg56.00€5mg119.00€10mg187.00€25mg316.00€50mg472.00€100mg658.00€500mg1,378.00€1mL*10mM (DMSO)114.00€Ribociclib succinate hydrate
CAS:Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).Formula:C27H38N8O6Purity:98%Color and Shape:SolidMolecular weight:570.651AMG 925 HCl
CAS:AMG 925 HCl is a selective and potent dual inhibitor of FLT3 (IC50: 2±1 nM) and CDK4 (IC50: 3±1 nM).Formula:C26H30ClN7O2Color and Shape:SolidMolecular weight:508.02GSK 3 Inhibitor IX
CAS:GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.Formula:C16H10BrN3O2Purity:98% - 99.72%Color and Shape:SolidMolecular weight:356.17Ref: TM-T1917
1mg42.00€2mg52.00€5mg78.00€10mg96.00€25mg216.00€50mg389.00€100mg577.00€500mg1,234.00€1mL*10mM (DMSO)86.00€CVT-313
CAS:CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.Formula:C20H28N6O3Purity:97.46% - 97.97%Color and Shape:SolidMolecular weight:400.47Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Formula:C16H16F3N5Purity:99.97%Color and Shape:SolidMolecular weight:335.33THZ2
CAS:THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).Formula:C31H28ClN7O2Purity:98.28%Color and Shape:SolidMolecular weight:566.05CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formula:C22H20BrN3O3SPurity:99.66%Color and Shape:SolidMolecular weight:486.38Ref: TM-T8930
2mg34.00€5mg50.00€10mg85.00€25mg159.00€50mg244.00€100mg359.00€200mg512.00€1mL*10mM (DMSO)55.00€CAN508
CAS:CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.Formula:C9H10N6OPurity:98.65%Color and Shape:SolidMolecular weight:218.22AMG 925
CAS:AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.Formula:C26H29N7O2Purity:99.75%Color and Shape:SolidMolecular weight:471.55SR-4835
CAS:SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (Formula:C21H20Cl2N10OPurity:98.09% - >99.99%Color and Shape:SolidMolecular weight:499.36AUZ 454
CAS:AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.Formula:C24H26F3N7O2Purity:99.59%Color and Shape:SolidMolecular weight:501.5PHA-793887
CAS:PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.Formula:C19H31N5O2Purity:98.02% - >99.99%Color and Shape:SolidMolecular weight:361.48Ref: TM-T2113
2mg34.00€5mg49.00€10mg75.00€25mg114.00€50mg185.00€100mg298.00€200mg444.00€1mL*10mM (DMSO)50.00€Fadraciclib
CAS:Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).Formula:C21H31N7OPurity:99.75%Color and Shape:SolidMolecular weight:397.52Ref: TM-TQ0053
1mg42.00€2mg55.00€5mg88.00€10mg145.00€25mg260.00€50mg414.00€100mg583.00€1mL*10mM (DMSO)87.00€BSJ-03-123
CAS:BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.Formula:C47H56N10O11Purity:97.78% - 99.38%Color and Shape:SolidMolecular weight:937.01Ref: TM-T5395
1mg87.00€2mg113.00€5mg177.00€10mg259.00€25mg409.00€50mg560.00€100mg800.00€500mg1,611.00€PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Formula:C20H27F2N5O4SPurity:98.77% - 99.55%Color and Shape:SolidMolecular weight:471.52Ref: TM-T8463
1mg54.00€5mg114.00€10mg178.00€25mg334.00€50mg557.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)118.00€THZ531
CAS:THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).Formula:C30H32ClN7O2Purity:97.17% - 99.86%Color and Shape:SolidMolecular weight:558.07Ref: TM-T4293
1mg59.00€2mg86.00€5mg105.00€10mg144.00€25mg313.00€50mg447.00€100mg650.00€500mg1,341.00€1mL*10mM (DMSO)130.00€Bohemine
CAS:Bohemine is a cyclin-dependent kinase inhibitor.Formula:C18H24N6OPurity:99.09% - 99.53%Color and Shape:SolidMolecular weight:340.42(E/Z)-Zotiraciclib citrate
(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.Formula:C29H32N4O8Color and Shape:SolidMolecular weight:564.59ML167
CAS:ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.
Formula:C19H17N3O3Purity:99.82% - >99.99%Color and Shape:SolidMolecular weight:335.36MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Formula:C17H18N4O3SPurity:99.84%Color and Shape:SolidMolecular weight:358.41Ref: TM-T5533
1mg52.00€5mg124.00€10mg177.00€25mg301.00€50mg424.00€100mg605.00€200mg797.00€1mL*10mM (DMSO)136.00€Voruciclib
CAS:Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large B-cell lymphoma.Formula:C22H19ClF3NO5Purity:99.89% - 99.99%Color and Shape:SolidMolecular weight:469.847BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17R547
CAS:R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.Formula:C18H21F2N5O4SPurity:90% - 99.64%Color and Shape:SolidMolecular weight:441.45Ref: TM-T6312
1mg48.00€5mg96.00€10mg140.00€25mg254.00€50mg487.00€100mg700.00€200mg973.00€1mL*10mM (DMSO)114.00€LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
Formula:C23H29ClN8OPurity:100%Color and Shape:SolidMolecular weight:469.026-(Dimethylamino)purine
CAS:6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitorFormula:C7H9N5Purity:99.01% - 99.77%Color and Shape:SolidMolecular weight:163.18Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Formula:C17H14N4Purity:99.74%Color and Shape:SolidMolecular weight:274.32Ref: TM-T5673
1mg34.00€5mg73.00€10mg94.00€25mg177.00€50mg323.00€100mg460.00€200mg622.00€1mL*10mM (DMSO)71.00€AZD-5597
CAS:AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent
Formula:C23H28FN7OPurity:98.01%Color and Shape:SolidMolecular weight:437.51Milciclib
CAS:Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.Formula:C25H32N8OPurity:99.28%Color and Shape:SolidMolecular weight:460.57Ref: TM-T6081
1mg49.00€5mg101.00€10mg168.00€25mg356.00€50mg572.00€100mg858.00€200mg1,153.00€1mL*10mM (DMSO)104.00€JNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formula:C15H12F2N6O3SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:394.36Ref: TM-T6126
1mg48.00€5mg100.00€10mg155.00€25mg268.00€50mg432.00€100mg595.00€200mg833.00€1mL*10mM (DMSO)94.00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formula:C22H32N6·HClPurity:99.21%Color and Shape:SolidMolecular weight:416.99Ref: TM-T6162
1mg37.00€2mg52.00€5mg79.00€10mg116.00€25mg250.00€50mg416.00€100mg645.00€200mgTo inquire1mL*10mM (DMSO)87.00€M2N12
CAS:M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.Formula:C20H16ClN5O2Purity:98.01%Color and Shape:SolidMolecular weight:393.83Ref: TM-T11929
1mg84.00€5mg152.00€10mg236.00€25mg447.00€50mg670.00€100mg982.00€1mL*10mM (DMSO)167.00€BS194
CAS:BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.Formula:C20H27N5O3Purity:99.85%Color and Shape:SolidMolecular weight:385.46AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurity:>99.99%Color and Shape:SolidMolecular weight:405.24Ref: TM-T8378
1mg124.00€2mg170.00€5mg260.00€10mg409.00€25mg677.00€50mg954.00€100mg1,288.00€1mL*10mM (DMSO)286.00€CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H14Cl3N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:358.67Ref: TM-T19913
1mg73.00€5mg128.00€10mg185.00€25mg299.00€50mg405.00€100mg545.00€1mL*10mM (DMSO)140.00€ALSTERPAULLONE
CAS:Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing EffecFormula:C16H11N3O3Purity:99.8%Color and Shape:SolidMolecular weight:293.28Ref: TM-T7426
1mg55.00€5mg110.00€10mg173.00€25mg296.00€50mg424.00€100mg587.00€200mg792.00€1mL*10mM (DMSO)105.00€Ribociclib
CAS:Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50：10/39 nM).Formula:C23H30N8OPurity:97.91% - >99.99%Color and Shape:SolidMolecular weight:434.54Ref: TM-T6199
2mg43.00€5mg64.00€10mg86.00€25mg97.00€50mg116.00€100mg168.00€500mg420.00€1mL*10mM (DMSO)69.00€SCH900776 (S-isomer)
CAS:SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).Formula:C15H18BrN7Purity:99.88%Color and Shape:SolidMolecular weight:376.25Ref: TM-T3700
1mg49.00€2mg70.00€5mg96.00€10mg155.00€25mg264.00€50mg424.00€100mg627.00€1mL*10mM (DMSO)114.00€NU2058
CAS:NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.Formula:C12H17N5OPurity:99.34% - 99.92%Color and Shape:SolidMolecular weight:247.3Ref: TM-T3186
10mg42.00€25mg78.00€50mg106.00€100mg160.00€200mg230.00€500mg378.00€1mL*10mM (DMSO)47.00€OTS964 hydrochloride
CAS:OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.Formula:C23H24N2O2S·HClPurity:96.5% - 98.03%Color and Shape:SolidMolecular weight:428.97Ref: TM-T4135
1mg46.00€2mg59.00€5mg93.00€10mg124.00€25mg197.00€50mg350.00€100mg522.00€1mL*10mM (DMSO)97.00€AG-494
CAS:AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Formula:C16H12N2O3Purity:98.69%Color and Shape:SolidMolecular weight:280.28AT7519 TFA
CAS:AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.Formula:C18H18Cl2F3N5O4Color and Shape:SolidMolecular weight:496.27Flavopiridol hydrochloride
CAS:Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.Formula:C21H21Cl2NO5Purity:98.87% - 99.88%Color and Shape:SolidMolecular weight:438.3Cdk5 Substrate acetate
Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.Formula:C55H103N15O14Purity:96.21%Color and Shape:SolidMolecular weight:1198.5Seliciclib
CAS:Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.Formula:C19H26N6OPurity:97.15% - 99.89%Color and Shape:White To Off-White SolidMolecular weight:354.45Palbociclib dihydrochloride
Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.Formula:C24H31Cl2N7O2Color and Shape:SolidMolecular weight:520.45CDK12-IN-5
CAS:CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Formula:C18H15F5N8OPurity:99.37%Color and Shape:SolidMolecular weight:454.36Ref: TM-T40290
1mg157.00€5mg378.00€10mg612.00€25mg1,251.00€50mg1,972.00€100mg2,673.00€1mL*10mM (DMSO)416.00€LSN2839567
CAS:LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Formula:C25H28F2N8Purity:99.14%Color and Shape:SolidMolecular weight:478.54(R)-(+)-O-Demethylbuchenavianine
CAS:(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, >10 μM, >10 μM, and >10 μM, respectively.Formula:C21H21NO4Color and Shape:SolidMolecular weight:351.40XL413
CAS:XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.Formula:C14H12ClN3O2Purity:98.40% - 99.94%Color and Shape:SolidMolecular weight:289.72Riviciclib hydrochloride
CAS:Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.Formula:C21H20ClNO5·HClPurity:99.51%Color and Shape:SolidMolecular weight:438.3SNX2-1-108
CAS:SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.Formula:C21H16N4Purity:98%Color and Shape:SolidMolecular weight:324.38
