CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Found 546 products of "CDK"
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RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:98% - 99.91%Color and Shape:SolidMolecular weight:545.63THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Formula:C31H28ClN7O2Purity:97.42% - 99.27%Color and Shape:SolidMolecular weight:566.05Bromosporine
CAS:Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formula:C17H20N6O4SPurity:99.65% - 99.79%Color and Shape:SolidMolecular weight:404.44Ref: TM-T6255
1mg44.00€2mg57.00€5mg93.00€10mg133.00€25mg260.00€50mg416.00€100mg665.00€200mg888.00€1mL*10mM (DMSO)92.00€PF-562271 besylate
CAS:PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formula:C21H20F3N7O3S·C6H6O3SPurity:97.65% - 99.01%Color and Shape:SolidMolecular weight:665.66Ref: TM-T6177
1mg35.00€5mg74.00€10mg94.00€25mg138.00€50mg198.00€100mg296.00€200mg427.00€1mL*10mM (DMSO)89.00€SR-4835
CAS:SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (Formula:C21H20Cl2N10OPurity:98.09% - >99.99%Color and Shape:SolidMolecular weight:499.36LY3405105
CAS:LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-Formula:C26H39N7O3Purity:99.66%Color and Shape:SolidMolecular weight:497.63PHA-767491 hydrochloride
CAS:PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.Formula:C12H12ClN3OPurity:99.56% - 99.92%Color and Shape:SolidMolecular weight:249.69Fadraciclib
CAS:Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).Formula:C21H31N7OPurity:99.75%Color and Shape:SolidMolecular weight:397.52Ref: TM-TQ0053
1mg42.00€2mg55.00€5mg88.00€10mg145.00€25mg260.00€50mg414.00€100mg583.00€1mL*10mM (DMSO)87.00€PF-562271
CAS:PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).Formula:C21H20F3N7O3SPurity:97.17% - >99.99%Color and Shape:SolidMolecular weight:507.49MSC2530818
CAS:MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).Formula:C18H17ClN4OPurity:98.93%Color and Shape:SolidMolecular weight:340.81Ref: TM-TQ0266
1mg63.00€5mg137.00€10mg215.00€25mg462.00€50mg692.00€100mg964.00€1mL*10mM (DMSO)150.00€JSH-150
CAS:JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).Formula:C24H33ClN6O2SPurity:99.96% - 99.96%Color and Shape:SolidMolecular weight:505.08Amantadine
CAS:Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.Formula:C10H17NPurity:99.73% - 99.94%Color and Shape:Hexakistetrahedral Crystals By Sublimation SolidMolecular weight:151.25TC11
CAS:TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosisFormula:C20H22N2O2Purity:97.86%Color and Shape:SolidMolecular weight:322.4AT7519 Hydrochloride
CAS:AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.Formula:C16H18Cl3N5O2Purity:99.66% - 99.9%Color and Shape:SolidMolecular weight:418.71Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFormula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24Dalpiciclib
CAS:Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.
Formula:C25H30N6O2Purity:99.69%Color and Shape:SolidMolecular weight:446.54NG 52
CAS:NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.Formula:C16H19ClN6OPurity:98% - 99.34%Color and Shape:SolidMolecular weight:346.81SCH900776 (S-isomer)
CAS:SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).Formula:C15H18BrN7Purity:99.88%Color and Shape:SolidMolecular weight:376.25Ref: TM-T3700
1mg50.00€2mg66.00€5mg90.00€10mg146.00€25mg250.00€50mg403.00€100mg593.00€1mL*10mM (DMSO)108.00€BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formula:C16H17N5Purity:90%Color and Shape:SolidMolecular weight:279.34CC-671
CAS:CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.Formula:C28H28N6O4Purity:98.66% - 98.8%Color and Shape:SolidMolecular weight:512.56Ref: TM-T4482
1mg50.00€5mg105.00€10mg170.00€25mg340.00€50mg512.00€100mg733.00€500mg1,513.00€1mL*10mM (DMSO)120.00€
