Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 261 products of "Microtubule Associated"
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TTBK1-IN-2
CAS:<p>TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.</p>Formula:C18H13ClN4OPurity:99.83%Color and Shape:SoildMolecular weight:336.77Tubulin inhibitor 48
CAS:<p>Tubulin inhibitor 48 (compound 16) is an anticancer agent targeting microtubules. It exhibits IC50 values of 0.1 μM and 0.07 μM against LN-229 and Capan-1 cells, respectively.</p>Formula:C21H22N4OColor and Shape:SolidMolecular weight:346.43Tubulin polymerization-IN-44
<p>Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it</p>Formula:C19H15Cl2N3O3SColor and Shape:SolidMolecular weight:436.31Trimethylcolchicinic acid
CAS:<p>Trimethylcolchicinic acid is an orally available colchicine analog that binds to tubulin and inhibits its polymerization into microtubules,potential antitumor.</p>Formula:C19H21NO5Purity:>99.99%Color and Shape:SoildMolecular weight:343.37Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formula:C83H127N25O34SPurity:98%Color and Shape:SolidMolecular weight:2051.11cis-trismethoxy Resveratrol
CAS:<p>cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.</p>Formula:C17H18O3Purity:99.88%Color and Shape:SolidMolecular weight:270.327-Epi-docetaxel
CAS:<p>7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.</p>Formula:C43H53NO14Purity:98%Color and Shape:SolidMolecular weight:807.88Epothilone F
CAS:<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formula:C27H41NO7SColor and Shape:SolidMolecular weight:523.68Vinblastine
CAS:<p>Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.</p>Formula:C46H58N4O9Purity:97.42%Color and Shape:PowderMolecular weight:810.97PM050489
CAS:<p>PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.</p>Formula:C31H44ClN3O7Color and Shape:SolidMolecular weight:606.15Anticancer agent 270
<p>Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.</p>Color and Shape:Odour Solid10-Oxo Docetaxel
CAS:<p>10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.</p>Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.874Phomopsinamine
CAS:<p>Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).</p>Formula:C32H43ClN6O8Color and Shape:SolidMolecular weight:675.177-Epi-10-oxo-docetaxel
CAS:<p>7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.</p>Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.86Vinflunine Tartrate
CAS:<p>Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.</p>Formula:C45H54F2N4O8·xC4H6O6Purity:98%Color and Shape:SolidMolecular weight:967.02Tubulin inhibitor 21
<p>Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.</p>Formula:C28H25N3O4SColor and Shape:SolidMolecular weight:499.58ALB-109564 dihydrochloride
CAS:<p>ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.</p>Formula:C47H62Cl2N4O9SPurity:98%Color and Shape:SolidMolecular weight:929.99Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Formula:C24H20FN3O3Color and Shape:SolidMolecular weight:417.43T-808
CAS:<p>T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.</p>Formula:C17H19FN4Color and Shape:SolidMolecular weight:298.36KGP591
<p>KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure</p>Formula:C24H21NO5Color and Shape:SolidMolecular weight:403.43Phomopsin A
CAS:<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Formula:C36H45ClN6O12Purity:98%Color and Shape:SolidMolecular weight:789.23Combretastatin A-1 phosphate tetrasodium
CAS:<p>OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.</p>Formula:C18H18Na4O12P2Color and Shape:SolidMolecular weight:580.24Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Formula:C16H13ClN6SColor and Shape:SolidMolecular weight:356.83Tubulin polymerization-IN-48
<p>Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.</p>Formula:C20H15Cl2N3OColor and Shape:SolidMolecular weight:384.26Tubulin inhibitor 37
<p>Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell</p>Formula:C16H10Cl2N6OColor and Shape:SolidMolecular weight:373.2Modified MMAF
CAS:<p>Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.</p>Formula:C45H73N7O8Color and Shape:SolidMolecular weight:840.1Tubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Formula:C22H25NO6Color and Shape:SolidMolecular weight:399.44TTBK1-IN-1
CAS:<p>TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.</p>Formula:C18H19N5O2Color and Shape:SolidMolecular weight:337.38PhosTAC7
CAS:<p>PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.</p>Formula:C58H87ClN2O17Purity:98.96%Color and Shape:SolidMolecular weight:1119.77Tirbanibulin dihydrochloride
CAS:<p>Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formula:C26H31Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:504.45Trifluralin
CAS:<p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>Formula:C13H16F3N3O4Purity:99.84%Color and Shape:Yellow-Orange Crystalline SolidMolecular weight:335.28colchiceine
CAS:<p>colchiceine has a wide range of applications in life science related research.</p>Formula:C21H23NO6Purity:99.38%Color and Shape:SolidMolecular weight:385.41BSc3094
CAS:<p>BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.</p>Formula:C17H12N6O3SColor and Shape:SolidMolecular weight:380.38Amiprofos methyl
CAS:<p>Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.</p>Formula:C11H17N2O4PSPurity:99.66%Color and Shape:SolidMolecular weight:304.30Oryzalin
CAS:<p>Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.</p>Formula:C12H18N4O6SPurity:99.86%Color and Shape:SolidMolecular weight:346.36Avanbulin
CAS:<p>Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.</p>Formula:C20H17N7O2Color and Shape:SolidMolecular weight:387.39Ombrabulin hydrochloride
CAS:<p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>Formula:C21H27ClN2O6Purity:98%Color and Shape:SolidMolecular weight:438.9TN-16
CAS:<p>TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)</p>Formula:C19H18N2O2Purity:99.54%Color and Shape:SolidMolecular weight:306.36Spastazoline
CAS:<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Formula:C20H30N8Purity:99.23%Color and Shape:SolidMolecular weight:382.51Vindesine sulfate
CAS:<p>Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.</p>Formula:C43H57N5O11SPurity:97.51%Color and Shape:Amorphous SolidMolecular weight:852N-Phenylbenzylamine
CAS:<p>A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization</p>Formula:C13H13NPurity:98.75%Color and Shape:Colorless To Pale Yellow Crystalline PowderMolecular weight:183.25Albendazole sulfoxide
CAS:<p>Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.</p>Formula:C12H15N3O3SPurity:97.29%Color and Shape:White To Off-White PowderMolecular weight:281.33Tau protein (592-597), Human TFA
<p>Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.</p>Formula:C36H63F3N10O11Purity:>99.99%Color and Shape:SolidMolecular weight:868.94Plinabulin
CAS:<p>Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).</p>Formula:C19H20N4O2Purity:98.69% - >99.99%Color and Shape:SolidMolecular weight:336.39MMAF
CAS:<p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>Formula:C39H65N5O8Purity:97.00% - 99.88%Color and Shape:SolidMolecular weight:731.96Parbendazole
CAS:<p>Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.</p>Formula:C13H17N3O2Purity:99.60%Color and Shape:Physical Description Crystals Or Fine White Powder (Ntp 1992)Molecular weight:247.29MAP4343
CAS:<p>Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.</p>Formula:C22H34O2Purity:97.024%Color and Shape:SolidMolecular weight:330.5Suprafenacine
CAS:<p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>Formula:C16H18N4OPurity:99.91%Color and Shape:SolidMolecular weight:282.34T807
CAS:<p>T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).</p>Formula:C16H10FN3Purity:99.72%Color and Shape:SolidMolecular weight:263.27D-64131
CAS:<p>D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.</p>Formula:C16H13NO2Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:251.28
