Microtubule Associated

Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.

Found 261 products of "Microtubule Associated"

Purity (%)

100

products per page.

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Anticancer agent 270
Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.
Color and Shape:Odour Solid
Ref: TM-T206688
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ALB-109564 dihydrochloride
CAS:
- 1300114-12-8
ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.
Formula:C₄₇H₆₂Cl₂N₄O₉S
Purity:98%
Color and Shape:Solid
Molecular weight:929.99
Ref: TM-T25025
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Tubulin inhibitor 24
CAS:
- 2415761-65-6
Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.
Formula:C₂₂H₂₁N₃O₃
Purity:99.99%
Color and Shape:Solid
Molecular weight:375.42
Ref: TM-T9812
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Dihydrocephalomannine
CAS:
- 159001-25-9
Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.
Formula:C₄₅H₅₅NO₁₄
Purity:98%
Color and Shape:Solid
Molecular weight:833.928
Ref: TM-T13653
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Combretastatin A-1 phosphate tetrasodium
CAS:
- 288847-34-7
OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.
Formula:C₁₈H₁₈Na₄O₁₂P₂
Color and Shape:Solid
Molecular weight:580.24
Ref: TM-T40367
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20-O-Demethyl-AP3
CAS:
- 72902-38-6
20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.
Formula:C₃₁H₄₁ClN₂O₉
Color and Shape:Solid
Molecular weight:621.12
Ref: TM-T40838
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Ceratamine A
CAS:
- 634151-15-8
Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.
Formula:C₁₇H₁₆Br₂N₄O₂
Purity:98%
Color and Shape:Solid
Molecular weight:468.14
Ref: TM-T10763
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Epothilone F
CAS:
- 208518-52-9
Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.
Formula:C₂₇H₄₁NO₇S
Color and Shape:Solid
Molecular weight:523.68
Ref: TM-T31657
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Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell
Formula:C₁₇H₁₃ClN₆OS
Color and Shape:Solid
Molecular weight:384.84
Ref: TM-T78773
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Phomopsinamine
CAS:
- 89085-54-1
Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).
Formula:C₃₂H₄₃ClN₆O₈
Color and Shape:Solid
Molecular weight:675.17
Ref: TM-T36855
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KGP591
KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure
Formula:C₂₄H₂₁NO₅
Color and Shape:Solid
Molecular weight:403.43
Ref: TM-T79408
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Tubulin polymerization-IN-48
Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.
Formula:C₂₀H₁₅Cl₂N₃O
Color and Shape:Solid
Molecular weight:384.26
Ref: TM-T79645
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Diminutol
CAS:
- 361431-33-6
Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.
Formula:C₁₉H₂₆N₆OS
Color and Shape:Solid
Molecular weight:386.51
Ref: TM-T36358
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Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,
Formula:C₁₆H₁₃ClN₆S
Color and Shape:Solid
Molecular weight:356.83
Ref: TM-T78771
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Pironetin
CAS:
- 151519-02-7
Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.
Formula:C₁₉H₃₂O₄
Purity:98%
Color and Shape:Solid
Molecular weight:324.45
Ref: TM-T16543
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PM050489
CAS:
- 960210-97-3
PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.
Formula:C₃₁H₄₄ClN₃O₇
Color and Shape:Solid
Molecular weight:606.15
Ref: TM-T75521
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Tubulin polymerization-IN-44
Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it
Formula:C₁₉H₁₅Cl₂N₃O₃S
Color and Shape:Solid
Molecular weight:436.31
Ref: TM-T79532
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Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast
Formula:C₂₂H₂₅NO₆
Color and Shape:Solid
Molecular weight:399.44
Ref: TM-T79629
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7-Epi-docetaxel
CAS:
- 153381-68-1
7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.
Formula:C₄₃H₅₃NO₁₄
Purity:98%
Color and Shape:Solid
Molecular weight:807.88
Ref: TM-TQ0247
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Microtubule-associated protein tau (26-44)
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.
Formula:C₈₃H₁₂₇N₂₅O₃₄S
Purity:98%
Color and Shape:Solid
Molecular weight:2051.11
Ref: TM-TP1420