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c-Myc

c-Myc

c-Myc inhibitors target the c-Myc protein, a transcription factor that plays a pivotal role in cell growth, proliferation, and apoptosis. c-Myc regulates the expression of numerous genes involved in the cell cycle and is often overexpressed in various cancers, leading to uncontrolled cell proliferation and tumor growth. Inhibiting c-Myc can disrupt these processes, inducing cell cycle arrest and apoptosis in cancer cells. c-Myc inhibitors are important tools in cancer research and therapeutic development. At CymitQuimica, we offer a wide range of high-quality c-Myc inhibitors to support your research in oncology, cell cycle regulation, and transcriptional control.

Found 69 products of "c-Myc"

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  • Ceramides Mixture

    CAS:
    <p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>
    Formula:C36H71NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:581.967
  • FIDAS-5

    CAS:
    <p>FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.</p>
    Formula:C15H13ClFN
    Purity:97.66% - 98.3%
    Color and Shape:Solid
    Molecular weight:261.72
  • Eragidomide

    CAS:
    <p>Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.</p>
    Formula:C22H18ClF2N3O4
    Purity:97.51% - 99.63%
    Color and Shape:Solid
    Molecular weight:461.85
  • MYCi361

    CAS:
    <p>MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).</p>
    Formula:C26H16ClF9N2O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:594.86
  • MYCMI-6

    CAS:
    <p>MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.</p>
    Formula:C20H19N7O
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:373.41
  • MYCi975

    CAS:
    <p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>
    Formula:C25H16Cl2F6N2O2
    Purity:99.3% - 99.82%
    Color and Shape:Solid
    Molecular weight:561.3
  • Saxagliptin hydrate

    CAS:
    <p>Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).</p>
    Formula:C18H25N3O2·H2O
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:333.43
  • KJ Pyr 9

    CAS:
    <p>KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).</p>
    Formula:C22H15N3O4
    Purity:99.56% - ≥98%
    Color and Shape:Solid
    Molecular weight:385.37
  • FIDAS-3

    CAS:
    <p>FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities</p>
    Formula:C16H15F2N
    Purity:97.75%
    Color and Shape:Solid
    Molecular weight:259.29
  • APTO-253

    CAS:
    <p>APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.</p>
    Formula:C22H14FN5
    Purity:98.73%
    Color and Shape:Solid
    Molecular weight:367.38
  • c-Myc inhibitor 10

    CAS:
    <p>c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.</p>
    Formula:C28H38N6O3
    Color and Shape:Solid
    Molecular weight:506.64
  • c-Myc inhibitor 5


    <p>DA3: Fluorescent c-Myc inhibitor, targets c-MYC G-quadruplex (K D 16 μM), selective, suppresses c-MYC expression.</p>
    Formula:C30H46N12
    Color and Shape:Solid
    Molecular weight:574.77
  • Anti-c-myc Antibody (9E10)


    <p>Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.</p>
    Color and Shape:Odour Liquid
  • Anticancer agent 263


    <p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>
    Formula:C13H20N2O6
    Color and Shape:Solid
    Molecular weight:300.308
  • Cotylenin A

    CAS:
    <p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>
    Formula:C33H50O11
    Color and Shape:Solid
    Molecular weight:622.744
  • H122


    <p>H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)</p>
    Formula:C45H45ClFN5O8
    Color and Shape:Solid
    Molecular weight:838.319
  • Methylcarbamyl PAF C-8


    <p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>
    Color and Shape:Odour Solid
  • RA-V


    <p>RA-V is a natural product that can be used as a reference standard.</p>
    Formula:C160H202N24O41
    Color and Shape:Solid
    Molecular weight:3117.5
  • VGN50


    <p>VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.</p>
    Formula:C121H218N46O32
    Molecular weight:2827.68453
  • MYC-IN-2

    CAS:
    <p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>
    Formula:C25H17N3O2S
    Color and Shape:Solid
    Molecular weight:423.49