PKC
PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 130 products for "PKC".
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D-ERYTHRO-SPHINGOSINE
CAS:D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activatorFormula:C18H37NO2Purity:98% - 99.85%Color and Shape:SolidMolecular weight:299.49Procyanidin A1
CAS:Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+.Formula:C30H24O12Purity:99.52%Color and Shape:SolidMolecular weight:576.50Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormula:C18H17Cl2FN4OSPurity:97.51% - 99.51%Color and Shape:SolidMolecular weight:427.32Ref: TM-T1911
1mg37.00€2mg52.00€5mg74.00€1mL*10mM (DMSO)74.00€10mg92.00€25mg166.00€50mg259.00€100mg452.00€500mg982.00€Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)Formula:C20H13N3O2Purity:98.83%Color and Shape:SolidMolecular weight:327.34Ref: TM-T7659
2mg39.00€5mg58.00€1mL*10mM (DMSO)64.00€10mg94.00€25mg167.00€50mg234.00€100mg326.00€200mg485.00€TPPB
CAS:TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).Formula:C27H30F3N3O3Purity:97.71% - 99.96%Color and Shape:Yellow SolidMolecular weight:501.54HA-100
CAS:HA-100 is an inhibitor of protein kinaseFormula:C13H15N3O2SPurity:99.44%Color and Shape:White SolidMolecular weight:277.34Ingenol
CAS:Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.Formula:C20H28O5Purity:99.78% - 99.87%Color and Shape:SolidMolecular weight:348.43Ref: TM-T5S2017
1mg49.00€5mg89.00€1mL*10mM (DMSO)90.00€10mg120.00€25mg234.00€50mg442.00€100mg605.00€500mg1,288.00€PKCβ inhibitor 1
CAS:PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,Formula:C24H21N5O2Purity:99.33%Color and Shape:Yellow SolidMolecular weight:411.46Ref: TM-T8376
500µg37.00€1mg52.00€5mg101.00€1mL*10mM (DMSO)110.00€10mg177.00€25mg391.00€50mg692.00€100mg945.00€Protein Kinase C 19-31 acetate
PKC 19-31 acetate, a serine-altered PKCa-derived PKC inhibitor, tests PKC activity.Formula:C69H122N26O18Purity:>99.99%Color and Shape:SolidMolecular weight:1603.9Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Formula:C30H16O8Purity:98.90% - ≥98%Color and Shape:Black SolidMolecular weight:504.44Ref: TM-T6S0923
1mg54.00€5mg120.00€1mL*10mM (DMSO)133.00€10mg172.00€25mg341.00€50mg504.00€100mg705.00€500mg1,431.00€Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formula:C32H29N5O2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:515.6Ruboxistaurin hydrochloride
CAS:Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Formula:C28H28N4O3·HClPurity:99.14% - 99.28%Color and Shape:Red SolidMolecular weight:505.01Ref: TM-T3689
1mg67.00€2mg87.00€5mg148.00€1mL*10mM (DMSO)190.00€10mg244.00€25mg487.00€50mg702.00€100mg982.00€500mg1,963.00€PKCTheta-IN-2
CAS:PKCTheta-IN-2 (compound 14) is a potent and selective PKCθ inhibitor (IC50 = 0.25 nM) that suppresses IL-2 production in mice (IC50 = 682 nM).Formula:C24H23N5O2Purity:99.38%Color and Shape:White SolidMolecular weight:413.47Ionomycin calcium
CAS:Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.Formula:C41H70CaO9Purity:98% - 98.11%Color and Shape:White SolidMolecular weight:747.07Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formula:C28H40O8Purity:99.32% - 99.37%Color and Shape:White SolidMolecular weight:504.61Ref: TM-T16526
1mg58.00€5mg160.00€1mL*10mM (DMSO)170.00€10mg268.00€25mg530.00€50mg827.00€100mg1,314.00€200mg1,773.00€PS315
CAS:PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.Formula:C23H19ClO2Purity:98%Color and Shape:SolidMolecular weight:362.85AJH-836
CAS:AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation ofFormula:C22H38O5Purity:98%Color and Shape:SolidMolecular weight:382.53SC-10
CAS:SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Formula:C17H22ClNO2SPurity:99.24% - 99.58%Color and Shape:White SolidMolecular weight:339.88CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurity:98.81% - 99.87%Color and Shape:Yellow SolidMolecular weight:355.82Ref: TM-T14943
1mg34.00€2mg46.00€5mg71.00€1mL*10mM (DMSO)78.00€10mg92.00€25mg177.00€50mg314.00€100mg518.00€
