PKC
PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 102 products of "PKC"
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Protein Kinase C 19-31 acetate
<p>PKC 19-31 acetate, a serine-altered PKCa-derived PKC inhibitor, tests PKC activity.</p>Formula:C69H122N26O18Purity:>99.99%Color and Shape:SolidMolecular weight:1603.9Hypericin
CAS:<p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>Formula:C30H16O8Purity:99.05% - ≥98%Color and Shape:Red-Coloured Anthraquinone-DerivativeMolecular weight:504.44Enzastaurin
CAS:<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Formula:C32H29N5O2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:515.6Ruboxistaurin hydrochloride
CAS:<p>Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.</p>Formula:C28H28N4O3·HClPurity:98.44% - 99.22%Color and Shape:SolidMolecular weight:505.01Ionomycin calcium
CAS:<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Formula:C41H70CaO9Purity:98% - 98.11%Color and Shape:SolidMolecular weight:747.07Phorbol 12,13-dibutyrate
CAS:<p>Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.</p>Formula:C28H40O8Purity:99.32% - 99.37%Color and Shape:SolidMolecular weight:504.61CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Formula:C18H18ClN5OPurity:98.81%Color and Shape:SolidMolecular weight:355.82PS315
CAS:<p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>Formula:C23H19ClO2Purity:98%Color and Shape:SolidMolecular weight:362.85SC-10
CAS:<p>SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.</p>Formula:C17H22ClNO2SPurity:99.24% - 99.58%Color and Shape:SolidMolecular weight:339.88AJH-836
CAS:<p>AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of</p>Formula:C22H38O5Purity:98%Color and Shape:SolidMolecular weight:382.53NSC668394
CAS:<p>NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.</p>Formula:C17H12Br2N2O3Purity:99.29% - 99.29%Color and Shape:SolidMolecular weight:452.1DCPLA-ME
CAS:<p>DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative</p>Formula:C21H38O2Purity:99.80%Color and Shape:SolidMolecular weight:322.53TCS 21311
CAS:<p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.</p>Formula:C27H25F3N4O4Purity:99.39% - ≥98%Color and Shape:SolidMolecular weight:526.51(-)-Indolactam V
CAS:<p>(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.</p>Formula:C17H23N3O2Purity:98%Color and Shape:SolidMolecular weight:301.38VTX-27
CAS:<p>VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).</p>Formula:C20H24ClFN6OPurity:99.84%Color and Shape:SolidMolecular weight:418.9PKC-θ inhibitor 1
CAS:<p>PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)</p>Formula:C17H15F3N4OPurity:98%Color and Shape:SolidMolecular weight:348.32PKC-IN-1
CAS:<p>PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,</p>Formula:C25H37FN8O2Purity:98% - 98.79%Color and Shape:SolidMolecular weight:500.61PKCTheta-IN-2
CAS:<p>PKCTheta-IN-2 (compound 14) is a potent and selective inhibitor of PKCθ, with an IC50 value of 0.25 nM. It demonstrates good selectivity across a broad range of kinases, including the PKC subfamily (30 kinases). Additionally, PKCTheta-IN-2 effectively inhibits the production of IL-2 in mice, where it exhibits an IC50 of 682 nM.</p>Formula:C24H23N5O2Color and Shape:SolidMolecular weight:413.47Dioleyl phosphatidylserine
CAS:<p>Dioleyl phosphatidylserine is a phospholipid that can activate PKC-γ (Protein Kinase C-gamma) when the Ca2+ concentration is below 0.5 μM, specifically at a concentration of 100 μM.</p>Formula:C42H78NO10PColor and Shape:SolidMolecular weight:788.04AS2521780
CAS:<p>AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).</p>Formula:C30H41N7OSPurity:98%Color and Shape:SolidMolecular weight:547.76
