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ROCK

ROCK (Rho-associated protein kinase) inhibitors target ROCK kinases, which are involved in the regulation of the cytoskeleton, cell shape, and motility. ROCK plays a significant role in the control of cell division, particularly in processes such as cytokinesis. Inhibiting ROCK can lead to changes in cell cycle dynamics, cell motility, and apoptosis, making these inhibitors valuable in cancer research, neurobiology, and cardiovascular studies. At CymitQuimica, we provide a selection of high-quality ROCK inhibitors to support your research in cell biology, cytoskeletal dynamics, and disease mechanisms.

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products per page. 71 products on this category.

BrandProduct dataPurityPrice rangeEstimated delivery
Targetmol logo
ZINC00881524
REF: TM-T4095CAS: 557782-81-7 		99.8%35.00 €~523.00 €Wed 11 Dec 24
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Fasudil hydrochloride
REF: TM-T3060CAS: 105628-07-7 		100% - ≥95%46.00 €~99.00 €Wed 11 Dec 24
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Afuresertib hydrochloride
REF: TM-T7885CAS: 1047645-82-8 		99.96%52.00 €~556.00 €Wed 11 Dec 24
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Rho-Kinase-IN-1
REF: TM-T12721CAS: 1035094-83-7 		99.51%72.00 €~2,654.00 €Wed 22 Jan 25
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H-1152
REF: TM-T7552CAS: 451462-58-1 		98%87.00 €~1,129.00 €Wed 22 Jan 25
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Rhodblock 6
REF: TM-T26078CAS: 886625-06-5 		98.27%52.00 €~2,256.00 €Wed 22 Jan 25
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Y-9738
REF: TM-T13972CAS: 59399-41-6 		98%907.00 €~2,337.00 €Wed 22 Jan 25
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CID-5056270
REF: TM-T23888CAS: 681173-76-2 		99.57%187.00 €~2,239.00 €Wed 22 Jan 25
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SB-747651A Dihydrochloride
REF: TM-T9652CAS: 1781882-72-1 		97.02%To inquireWed 22 Jan 25
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CAY10746
REF: TM-T36196CAS: 2247240-76-0 		99.04%52.00 €~3,573.00 €Wed 22 Jan 25
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CRT0066854 hydrochloride
REF: TM-T10888CAS: 2250019-91-9 		97.51%39.00 €~2,191.00 €Wed 22 Jan 25
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AS 1892802
REF: TM-T22037CAS: 928320-12-1 		98.9%52.00 €~1,616.00 €Wed 22 Jan 25
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SB-772077B dihydrochloride
REF: TM-T16855CAS: 607373-46-6 		98%73.00 €~1,049.00 €Wed 22 Jan 25
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ROCK2-IN-6
REF: TM-T79832CAS: 2260506-59-8 		98%To inquireWed 05 Feb 25
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ROCK-IN-8
REF: TM-T79809CAS: 1621103-79-4 		98%To inquireWed 05 Feb 25
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ROCK2-IN-6 hydrochloride
REF: TM-T78205CAS: 2762238-94-6 		98%To inquireWed 05 Feb 25
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Chroman 1
REF: TM-T14960CAS: 1273579-40-0 		99.28% - 99.91%75.00 €~922.00 €Wed 05 Feb 25
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ROCK2-IN-2
REF: TM-T12747CAS: 1995065-79-6 		98.45%51.00 €~903.00 €Wed 05 Feb 25
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ROCK-IN-1
REF: TM-T13419CAS: 934387-35-6 		100%117.00 €~1,504.00 €Wed 05 Feb 25
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Netarsudil mesylate
REF: TM-T10358L2CAS: 1422144-42-0 		98%300.00 €~1,282.00 €Wed 05 Feb 25
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ZINC00881524
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ZINC00881524

CAS:557782-81-7
ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
Formula:
C21H20N2O3S
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
380.46

Ref: TM-T4095

5mg35.00 €
10mg51.00 €
25mg95.00 €
50mg143.00 €
100mg212.00 €
500mg523.00 €
1mL*10mM (DMSO)36.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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Fasudil hydrochloride
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Fasudil hydrochloride

CAS:105628-07-7
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki …
Formula:
C14H18ClN3O2S
Purity:
100% - ≥95%
Color and Shape:
White Solid
Molecular weight:
327.83

Ref: TM-T3060

50mg46.00 €
100mg54.00 €
200mg79.00 €
500mg99.00 €
1mL*10mM (DMSO)55.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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Afuresertib hydrochloride
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Afuresertib hydrochloride

CAS:1047645-82-8
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Formula:
C18H18Cl3FN4OS
Purity:
99.96%
Color and Shape:
Solid
Molecular weight:
463.8

Ref: TM-T7885

2mg52.00 €
5mg74.00 €
10mg93.00 €
25mg161.00 €
50mg247.00 €
100mg429.00 €
200mg556.00 €
1mL*10mM (DMSO)85.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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Rho-Kinase-IN-1
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Rho-Kinase-IN-1

CAS:1035094-83-7
Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research …
Formula:
C20H24N4S
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
352.5

Ref: TM-T12721

1mg72.00 €
5mg141.00 €
10mg208.00 €
25mg364.00 €
50mg510.00 €
100mg676.00 €
200mg909.00 €
1mL*10mM (DMSO)107.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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H-1152
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H-1152

CAS:451462-58-1
H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).
Formula:
C16H21N3O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
319.42

Ref: TM-T7552

1mg162.00 €
5mg650.00 €
10mg1,129.00 €
500µg87.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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Rhodblock 6
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Rhodblock 6

CAS:886625-06-5
Rhodblock 6 is a Rho kinase inhibitor, blocking phosphorylated MRLC localization by targeting ROCK activity.
Formula:
C12H13N3O
Purity:
98.27%
Color and Shape:
Solid
Molecular weight:
215.25

Ref: TM-T26078

1mg52.00 €
5mg101.00 €
10mg163.00 €
25mg333.00 €
50mg493.00 €
100mg702.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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Y-9738
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Y-9738

CAS:59399-41-6
Y-9738 is an agent of hypolipidemic.
Formula:
C15H16ClNO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
309.74

Ref: TM-T13972

25mg1,410.00 €
50mg1,851.00 €
100mg2,337.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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CID-5056270
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CID-5056270

CAS:681173-76-2
CID-5056270 has anticancer activity and can inhibit lung cancer, anal cancer, bladder cancer, cervical cancer, …
Formula:
C17H13N3O3S
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
339.37

Ref: TM-T23888

1mg187.00 €
5mg453.00 €
10mg617.00 €
25mg936.00 €
50mg1,257.00 €
100mg1,653.00 €
200mg2,239.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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SB-747651A Dihydrochloride
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SB-747651A Dihydrochloride

CAS:1781882-72-1
SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in …
Formula:
C16H24Cl2N8O
Purity:
97.02%
Color and Shape:
Liquid
Molecular weight:
415.32

Ref: TM-T9652

1mg72.00 €
5mg152.00 €
10mg215.00 €
25mg361.00 €
50mg515.00 €
100mg698.00 €
500mgTo inquire
1mL*10mM (DMSO)168.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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CAY10746
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CAY10746

CAS:2247240-76-0
CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.
Formula:
C26H23N3O5
Purity:
99.04%
Color and Shape:
Solid
Molecular weight:
457.48

Ref: TM-T36196

1mg52.00 €
5mg119.00 €
10mg184.00 €
25mg423.00 €
50mg640.00 €
100mg1,012.00 €
200mg1,368.00 €
1mL*10mM (DMSO)119.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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CRT0066854 hydrochloride
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CRT0066854 hydrochloride

CAS:2250019-91-9
CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.
Formula:
C24H27Cl2N5S
Purity:
97.51%
Color and Shape:
Solid
Molecular weight:
488.48

Ref: TM-T10888

1mg39.00 €
2mg51.00 €
5mg83.00 €
10mg122.00 €
25mg200.00 €
50mg297.00 €
100mg423.00 €
1mL*10mM (DMSO)92.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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discount label
AS 1892802
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AS 1892802

CAS:928320-12-1
AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive …
Formula:
C20H19N3O2
Purity:
98.9%
Color and Shape:
Solid
Molecular weight:
333.38

Ref: TM-T22037

1mg52.00 €
5mg95.00 €
10mg171.00 €
25mg369.00 €
50mg547.00 €
100mg786.00 €
500mg1,616.00 €
1mL*10mM (DMSO)163.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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SB-772077B dihydrochloride
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SB-772077B dihydrochloride

CAS:607373-46-6
SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward …
Formula:
C15H20Cl2N8O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
415.28

Ref: TM-T16855

2mg91.00 €
5mg172.00 €
50mg738.00 €
100mg1,049.00 €
1mL*10mM (DMSO)203.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025
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ROCK2-IN-6
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ROCK2-IN-6

CAS:2260506-59-8
ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment …
Formula:
C26H21F2N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
485.49

Ref: TM-T79832

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Wednesday 5 Feb 2025
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ROCK-IN-8
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ROCK-IN-8

CAS:1621103-79-4
ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and …
Formula:
C30H25FN4O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
556.61

Ref: TM-T79809

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Wednesday 5 Feb 2025
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ROCK2-IN-6 hydrochloride
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ROCK2-IN-6 hydrochloride

CAS:2762238-94-6
ROCK2-IN-6 hydrochloride (Comp A) serves as a selective inhibitor of ROCK2, applicable for research into …
Formula:
C26H22ClF2N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
521.95

Ref: TM-T78205

2mg271.00 €
Estimated delivery in United States, on Wednesday 5 Feb 2025
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Chroman 1
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Chroman 1

CAS:1273579-40-0
Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 …
Formula:
C24H28N4O4
Purity:
99.28% - 99.91%
Color and Shape:
Solid
Molecular weight:
436.5

Ref: TM-T14960

1mg75.00 €
5mg167.00 €
10mg259.00 €
25mg477.00 €
50mg689.00 €
100mg922.00 €
1mL*10mM (DMSO)183.00 €
Estimated delivery in United States, on Wednesday 5 Feb 2025
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ROCK2-IN-2
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ROCK2-IN-2

CAS:1995065-79-6
ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).
Formula:
C18H12N6OS
Purity:
98.45%
Color and Shape:
Solid
Molecular weight:
360.39

Ref: TM-T12747

1mg51.00 €
5mg113.00 €
10mg181.00 €
25mg309.00 €
50mg454.00 €
100mg703.00 €
200mg903.00 €
1mL*10mM (DMSO)139.00 €
Estimated delivery in United States, on Wednesday 5 Feb 2025
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ROCK-IN-1
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ROCK-IN-1

CAS:934387-35-6
ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of …
Formula:
C20H18FN3O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
335.37

Ref: TM-T13419

1mg117.00 €
5mg269.00 €
10mg462.00 €
25mg916.00 €
50mg1,504.00 €
Estimated delivery in United States, on Wednesday 5 Feb 2025
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discount label
Netarsudil mesylate
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Netarsudil mesylate

CAS:1422144-42-0
Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and …
Formula:
C30H35N3O9S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
645.74

Ref: TM-T10358L2

25mg300.00 €
50mg483.00 €
100mg856.00 €
Estimated delivery in United States, on Wednesday 5 Feb 2025
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