ROCK
ROCK (Rho-associated protein kinase) inhibitors target ROCK kinases, which are involved in the regulation of the cytoskeleton, cell shape, and motility. ROCK plays a significant role in the control of cell division, particularly in processes such as cytokinesis. Inhibiting ROCK can lead to changes in cell cycle dynamics, cell motility, and apoptosis, making these inhibitors valuable in cancer research, neurobiology, and cardiovascular studies. At CymitQuimica, we provide a selection of high-quality ROCK inhibitors to support your research in cell biology, cytoskeletal dynamics, and disease mechanisms.
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Neoprzewaquinone A
CAS:630057-39-5
Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and …
Formula:
C36H28O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
556.6
Ref: TM-TN1985
| 1mg | 212.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Y-33075 dihydrochloride
CAS:173897-44-4
Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).
Formula:
C16H18Cl2N4O
Purity:
98.88% - 99.1%
Color and Shape:
Solid
Molecular weight:
353.25
Ref: TM-T13384L
| 2mg | 45.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 527.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Netarsudil Dihydrochloride
CAS:1253952-02-1
Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-related protein kinase (ROCK) and norepinephrine transporter …
Formula:
C28H29Cl2N3O3
Purity:
99.94% - 99.98%
Color and Shape:
Solid
Molecular weight:
526.45
Ref: TM-T10358
| 1mg | 53.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 292.00 € | ||
| 50mg | 484.00 € | ||
| 100mg | 842.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
ROCK inhibitor-2
CAS:1127308-52-4
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM …
Formula:
C21H20N2O2
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
332.4
Ref: TM-T12746
| 1mg | 65.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 423.00 € | ||
| 50mg | 630.00 € | ||
| 100mg | 884.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CMPD101
CAS:865608-11-3
CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).
Formula:
C24H21F3N6O
Purity:
98.34% - 99.01%
Color and Shape:
Solid
Molecular weight:
466.46
Ref: TM-T14989
| 1mg | 65.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 193.00 € | ||
| 25mg | 389.00 € | ||
| 50mg | 582.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Akt/ROCK-IN-1
Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 …
Formula:
C21H19BrF2N4O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
509.37
Ref: TM-T79905
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Cucurbitacin A
CAS:6040-19-3
Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates …
Formula:
C32H46O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
574.7
Ref: TM-TN1533
| 5mg | 942.00 € | ||
| 1mL*10mM (DMSO) | 1,225.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Ripasudil free base
CAS:223645-67-8
Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a …
Formula:
C15H18FN3O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
323.39
Ref: TM-T7492
| 1mg | 80.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 555.00 € | ||
| 50mg | 916.00 € | ||
| 100mg | 1,531.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ROCK-IN-5
CAS:692870-25-0
ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.
Formula:
C16H11ClFN3OS
Purity:
99.03% - 99.69%
Color and Shape:
Liquid
Molecular weight:
347.79
Ref: TM-T67748
| 10mg | 45.00 € | ||
| 25mg | 68.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 132.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Fasudil
CAS:103745-39-7
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
Formula:
C14H17N3O2S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
291.37
Ref: TM-T1606
| 50mg | 39.00 € | ||
| 100mg | 49.00 € | ||
| 200mg | 67.00 € | ||
| 500mg | 104.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
WAY-656935
CAS:852902-81-9
WAY-656935 inhibits ROCK.
Formula:
C20H28ClN3O3S
Purity:
98.1%
Color and Shape:
Solid
Molecular weight:
425.97
Ref: TM-T77609
| 1mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 162.00 € | ||
| 25mg | 347.00 € | ||
| 50mg | 514.00 € | ||
| 100mg | 744.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
GKI-1 HCl
GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect …
Formula:
C15H13Cl2N3
Purity:
98.44%
Color and Shape:
Soild
Molecular weight:
306.19
Ref: TM-T11402L
| 1mg | 155.00 € | ||
| 5mg | 367.00 € | ||
| 10mg | 547.00 € | ||
| 25mg | 870.00 € | ||
| 50mg | 1,180.00 € | ||
| 100mg | 1,569.00 € | ||
| 500mg | 3,183.00 € | ||
| 1mL*10mM (DMSO) | 417.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ROCK2-IN-9
ROCK2-IN-9 (compound 7u), a selective ROCK2 inhibitor with an IC50 value of 36.8 nM, demonstrates …
Formula:
C28H30N8O2
Color and Shape:
Liquid
Molecular weight:
510.59
Ref: TM-T200128
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
LX-7101 hydrochloride
CAS:1374644-80-0
LX-7101 hydrochloride is a potent LIMK and ROCK2 inhibitor with antihypertensive activity, inhibits LIMK1/2, ROCK, …
Formula:
C23H29N7O3xHCl
Purity:
98.35%
Color and Shape:
Solid
Molecular weight:
487.99
Ref: TM-T32985
| 1mg | 182.00 € | ||
| 5mg | 451.00 € | ||
| 10mg | 646.00 € | ||
| 25mg | 1,007.00 € | ||
| 50mg | 1,390.00 € | ||
| 100mg | 1,837.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Verosudil
CAS:1414854-42-4
Verosudil (AR-12286), a ROCK1/2 inhibitor (Ki: 2 nM), lowers intraocular pressure in mice by enhancing …
Formula:
C17H17N3O2S
Purity:
99.72%
Color and Shape:
Liquid
Molecular weight:
327.4
Ref: TM-T60924
| 1mg | 96.00 € | ||
| 5mg | 246.00 € | ||
| 10mg | 399.00 € | ||
| 25mg | 641.00 € | ||
| 50mg | 898.00 € | ||
| 100mg | 1,196.00 € | ||
| 1mL*10mM (DMSO) | 268.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cotosudil
CAS:1258833-31-6
Cotosudil is a ROCK kinase inhibitor with antihypertensive activity used to treat or prevent neurodegenerative …
Formula:
C16H21N3O2S
Purity:
98.41%
Color and Shape:
Liquid
Molecular weight:
319.42
Ref: TM-T38654
| 1mg | 102.00 € | ||
| 5mg | 244.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 630.00 € | ||
| 50mg | 890.00 € | ||
| 1mL*10mM (DMSO) | 268.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RKI1313
CAS:1342276-76-9
RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, …
Formula:
C17H16N4O2S
Purity:
99.06% - ≥95%
Color and Shape:
Solid
Molecular weight:
340.4
Ref: TM-T2011
| 1mg | 72.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 205.00 € | ||
| 25mg | 366.00 € | ||
| 50mg | 549.00 € | ||
| 100mg | 824.00 € | ||
| 1mL*10mM (DMSO) | 588.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Hydroxyfasudil Hydrochloride
CAS:155558-32-0
Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).
Formula:
C14H18ClN3O3S
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
343.83
Ref: TM-T4276
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 149.00 € | ||
| 100mg | 268.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GSK180736A
CAS:817194-38-0
GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong …
Formula:
C19H16FN5O2
Purity:
98.16% - 98.44%
Color and Shape:
Solid
Molecular weight:
365.36
Ref: TM-T3513
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 555.00 € | ||
| 500mg | 1,203.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Thiazovivin
CAS:1226056-71-8
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.
Formula:
C15H13N5OS
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
311.36
Ref: TM-T2155
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 555.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
