ROCK
ROCK (Rho-associated protein kinase) inhibitors target ROCK kinases, which are involved in the regulation of the cytoskeleton, cell shape, and motility. ROCK plays a significant role in the control of cell division, particularly in processes such as cytokinesis. Inhibiting ROCK can lead to changes in cell cycle dynamics, cell motility, and apoptosis, making these inhibitors valuable in cancer research, neurobiology, and cardiovascular studies. At CymitQuimica, we provide a selection of high-quality ROCK inhibitors to support your research in cell biology, cytoskeletal dynamics, and disease mechanisms.
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Neoprzewaquinone A
CAS:630057-39-5
Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and …
Formula:
C36H28O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
556.6
Ref: TM-TN1985
| 1mg | 212.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Y-33075 dihydrochloride
CAS:173897-44-4
Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).
Formula:
C16H18Cl2N4O
Purity:
98.88% - 99.1%
Color and Shape:
Solid
Molecular weight:
353.25
Ref: TM-T13384L
| 2mg | 45.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 527.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ROCK inhibitor-2
CAS:1127308-52-4
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM …
Formula:
C21H20N2O2
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
332.4
Ref: TM-T12746
| 1mg | 65.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 423.00 € | ||
| 50mg | 630.00 € | ||
| 100mg | 884.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CMPD101
CAS:865608-11-3
CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).
Formula:
C24H21F3N6O
Purity:
98.34% - 99.01%
Color and Shape:
Solid
Molecular weight:
466.46
Ref: TM-T14989
| 1mg | 65.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 193.00 € | ||
| 25mg | 389.00 € | ||
| 50mg | 582.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Netarsudil Dihydrochloride
CAS:1253952-02-1
Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-related protein kinase (ROCK) and norepinephrine transporter …
Formula:
C28H29Cl2N3O3
Purity:
99.94% - 99.98%
Color and Shape:
Solid
Molecular weight:
526.45
Ref: TM-T10358
| 1mg | 53.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 292.00 € | ||
| 50mg | 484.00 € | ||
| 100mg | 842.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
WAY-656935
CAS:852902-81-9
WAY-656935 inhibits ROCK.
Formula:
C20H28ClN3O3S
Purity:
98.1%
Color and Shape:
Liquid
Molecular weight:
425.97
Ref: TM-T77609
| 1mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 162.00 € | ||
| 25mg | 347.00 € | ||
| 50mg | 514.00 € | ||
| 100mg | 744.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Ripasudil free base
CAS:223645-67-8
Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a …
Formula:
C15H18FN3O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
323.39
Ref: TM-T7492
| 1mg | 80.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 555.00 € | ||
| 50mg | 916.00 € | ||
| 100mg | 1,531.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
LX-7101 hydrochloride
CAS:1374644-80-0
LX-7101 hydrochloride is a potent LIMK and ROCK2 inhibitor with antihypertensive activity, inhibits LIMK1/2, ROCK, …
Formula:
C23H29N7O3xHCl
Purity:
98.35%
Color and Shape:
Solid
Molecular weight:
487.99
Ref: TM-T32985
| 1mg | 182.00 € | ||
| 5mg | 451.00 € | ||
| 10mg | 646.00 € | ||
| 25mg | 1,007.00 € | ||
| 50mg | 1,390.00 € | ||
| 100mg | 1,837.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ROCK2-IN-9
ROCK2-IN-9 (compound 7u), a selective ROCK2 inhibitor with an IC50 value of 36.8 nM, demonstrates …
Formula:
C28H30N8O2
Color and Shape:
Liquid
Molecular weight:
510.59
Ref: TM-T200128
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Akt/ROCK-IN-1
Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 …
Formula:
C21H19BrF2N4O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
509.37
Ref: TM-T79905
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Fasudil
CAS:103745-39-7
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
Formula:
C14H17N3O2S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
291.37
Ref: TM-T1606
| 50mg | 39.00 € | ||
| 100mg | 49.00 € | ||
| 200mg | 67.00 € | ||
| 500mg | 104.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
GKI-1 HCl
GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect …
Formula:
C15H13Cl2N3
Purity:
98.44%
Color and Shape:
Soild
Molecular weight:
306.19
Ref: TM-T11402L
| 1mg | 155.00 € | ||
| 5mg | 367.00 € | ||
| 10mg | 547.00 € | ||
| 25mg | 870.00 € | ||
| 50mg | 1,180.00 € | ||
| 100mg | 1,569.00 € | ||
| 500mg | 3,183.00 € | ||
| 1mL*10mM (DMSO) | 417.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ROCK-IN-5
CAS:692870-25-0
ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.
Formula:
C16H11ClFN3OS
Purity:
99.03% - 99.69%
Color and Shape:
Liquid
Molecular weight:
347.79
Ref: TM-T67748
| 10mg | 45.00 € | ||
| 25mg | 68.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 132.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Cucurbitacin A
CAS:6040-19-3
Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates …
Formula:
C32H46O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
574.7
Ref: TM-TN1533
| 5mg | 942.00 € | ||
| 1mL*10mM (DMSO) | 1,225.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Verosudil
CAS:1414854-42-4
Verosudil (AR-12286), a ROCK1/2 inhibitor (Ki: 2 nM), lowers intraocular pressure in mice by enhancing …
Formula:
C17H17N3O2S
Purity:
99.72%
Color and Shape:
Liquid
Molecular weight:
327.4
Ref: TM-T60924
| 1mg | 96.00 € | ||
| 5mg | 246.00 € | ||
| 10mg | 399.00 € | ||
| 25mg | 641.00 € | ||
| 50mg | 898.00 € | ||
| 100mg | 1,196.00 € | ||
| 1mL*10mM (DMSO) | 268.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
GSK269962A hydrochloride
CAS:2095432-71-4
GSK269962A hydrochloride (GSK 269962 hydrochloride) is a ROCK inhibitor with anti-inflammatory and vasodilatory effects and …
Formula:
C29H31ClN8O5
Color and Shape:
Solid
Molecular weight:
607.06
Ref: TM-T39519
| 5mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Cotosudil
CAS:1258833-31-6
Cotosudil is a ROCK kinase inhibitor with antihypertensive activity used to treat or prevent neurodegenerative …
Formula:
C16H21N3O2S
Purity:
98.41%
Color and Shape:
Liquid
Molecular weight:
319.42
Ref: TM-T38654
| 1mg | 102.00 € | ||
| 5mg | 244.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 630.00 € | ||
| 50mg | 890.00 € | ||
| 1mL*10mM (DMSO) | 268.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Belumosudil mesylate
CAS:2109704-99-4
Belumosudil mesylate is a ROCK2 inhibitor (IC50: 105 nM) with weaker effect on ROCK1 (IC50: …
Formula:
C27H28N6O5S
Color and Shape:
Liquid
Molecular weight:
548.61
Ref: TM-T39555
| 1mg | 37.00 € | ||
| 5mg | 76.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 175.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 381.00 € | ||
| 500mg | 906.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CCG-222740
CAS:1922098-69-8
CCG-222740 is an inhibitor of Rho/MRTF pathway
Formula:
C23H19ClF2N2O3
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
444.86
Ref: TM-T7764
| 2mg | 41.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 402.00 € | ||
| 200mg | 570.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
RKI-1447
CAS:1342278-01-6
RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.
Formula:
C16H14N4O2S
Purity:
98% - 99.73%
Color and Shape:
Solid
Molecular weight:
326.37
Ref: TM-T1898
| 5mg | 51.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 404.00 € | ||
| 200mg | 509.00 € | ||
| 500mg | 822.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
