ROCK
ROCK (Rho-associated protein kinase) inhibitors target ROCK kinases, which are involved in the regulation of the cytoskeleton, cell shape, and motility. ROCK plays a significant role in the control of cell division, particularly in processes such as cytokinesis. Inhibiting ROCK can lead to changes in cell cycle dynamics, cell motility, and apoptosis, making these inhibitors valuable in cancer research, neurobiology, and cardiovascular studies. At CymitQuimica, we provide a selection of high-quality ROCK inhibitors to support your research in cell biology, cytoskeletal dynamics, and disease mechanisms.
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Netarsudil mesylate
CAS:1422144-42-0
Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and …
Formula:
C30H35N3O9S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
645.74
Ref: TM-T10358L2
| 1mg | 65.00 € | ||
| 5mg | 133.00 € | ||
| 10mg | 189.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 483.00 € | ||
| 100mg | 856.00 € | ||
| 200mg | 1,223.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
HA-100
CAS:84468-24-6
HA-100 is an inhibitor of protein kinase
Formula:
C13H15N3O2S
Purity:
99.44%
Color and Shape:
Pale Yellow Crystalline Solid
Molecular weight:
277.34
Ref: TM-T7648
| 5mg | 62.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 531.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
RKI1313
CAS:1342276-76-9
RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, …
Formula:
C17H16N4O2S
Purity:
99.06% - ≥95%
Color and Shape:
Solid
Molecular weight:
340.4
Ref: TM-T2011
| 1mg | 72.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 205.00 € | ||
| 25mg | 366.00 € | ||
| 50mg | 549.00 € | ||
| 100mg | 824.00 € | ||
| 1mL*10mM (DMSO) | 588.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Hydroxyfasudil
CAS:105628-72-6
Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, …
Formula:
C14H17N3O3S
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
307.37
Ref: TM-T4276L
| 5mg | 41.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 152.00 € | ||
| 100mg | 232.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
GSK429286A
CAS:864082-47-3
GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).
Formula:
C21H16F4N4O2
Purity:
97.68% - 98.42%
Color and Shape:
Solid
Molecular weight:
432.37
Ref: TM-T2633
| 2mg | 41.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 134.00 € | ||
| 50mg | 206.00 € | ||
| 100mg | 348.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
SAR407899 hydrochloride
CAS:923262-96-8
SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 …
Formula:
C14H17ClN2O2
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
280.75
Ref: TM-T23308
| 5mg | 34.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 126.00 € | ||
| 100mg | 195.00 € | ||
| 200mg | 287.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
URMC-099
CAS:1229582-33-5
URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 - MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.
Formula:
C27H27N5
Purity:
98.43% - 99.32%
Color and Shape:
Solid
Molecular weight:
421.54
Ref: TM-T6057
| 5mg | 56.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 371.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
SAR407899
CAS:923359-38-0
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
Formula:
C14H16N2O2
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
244.29
Ref: TM-T7391
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 369.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
CKI-7
CAS:1177141-67-1
CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; …
Formula:
C11H14Cl3N3O2S
Purity:
100.00% - 100.00%
Color and Shape:
Solid
Molecular weight:
358.67
Ref: TM-T19913
| 1mg | 116.00 € | ||
| 5mg | 220.00 € | ||
| 10mg | 330.00 € | ||
| 25mg | 531.00 € | ||
| 50mg | 720.00 € | ||
| 100mg | 970.00 € | ||
| 200mg | 1,246.00 € | ||
| 1mL*10mM (DMSO) | 241.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
AT13148
CAS:1056901-62-2
AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
Formula:
C17H16ClN3O
Purity:
98.04% - ≥95%
Color and Shape:
Solid
Molecular weight:
313.78
Ref: TM-T2482
| 1mg | 48.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 117.00 € | ||
| 10mg | 189.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 476.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
ROCK-IN-2
CAS:867017-68-3
ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and …
Formula:
C18H13ClF2N6O
Purity:
97.29%
Color and Shape:
Solid
Molecular weight:
402.79
Ref: TM-TQ0110
| 1mg | 112.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 433.00 € | ||
| 25mg | 712.00 € | ||
| 50mg | 994.00 € | ||
| 100mg | 1,346.00 € | ||
| 1mL*10mM (DMSO) | 370.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Narciclasine
CAS:29477-83-6
Narciclasine (Lycoricidinol), a natural product, modulates the Rho/Rho-kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA …
Formula:
C14H13NO7
Purity:
98.79% - 99.58%
Color and Shape:
Solid
Molecular weight:
307.26
Ref: TM-TQ0183
| 1mg | 99.00 € | ||
| 5mg | 406.00 € | ||
| 10mg | 592.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 447.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
ZINC00881524
CAS:557782-81-7
ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
Formula:
C21H20N2O3S
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
380.46
Ref: TM-T4095
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 143.00 € | ||
| 100mg | 212.00 € | ||
| 500mg | 523.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Fasudil hydrochloride
CAS:105628-07-7
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki …
Formula:
C14H18ClN3O2S
Purity:
100% - ≥95%
Color and Shape:
White Solid
Molecular weight:
327.83
Ref: TM-T3060
| 50mg | 46.00 € | ||
| 100mg | 54.00 € | ||
| 200mg | 79.00 € | ||
| 500mg | 99.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Afuresertib hydrochloride
CAS:1047645-82-8
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Formula:
C18H18Cl3FN4OS
Purity:
99.96%
Color and Shape:
Solid
Molecular weight:
463.8
Ref: TM-T7885
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 161.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 429.00 € | ||
| 200mg | 556.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Hydroxyfasudil Hydrochloride
CAS:155558-32-0
Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).
Formula:
C14H18ClN3O3S
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
343.83
Ref: TM-T4276
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 149.00 € | ||
| 100mg | 268.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
GSK180736A
CAS:817194-38-0
GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong …
Formula:
C19H16FN5O2
Purity:
98.16% - 98.44%
Color and Shape:
Solid
Molecular weight:
365.36
Ref: TM-T3513
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 555.00 € | ||
| 500mg | 1,203.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Thiazovivin
CAS:1226056-71-8
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.
Formula:
C15H13N5OS
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
311.36
Ref: TM-T2155
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 555.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
CCG-222740
CAS:1922098-69-8
CCG-222740 is an inhibitor of Rho/MRTF pathway
Formula:
C23H19ClF2N2O3
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
444.86
Ref: TM-T7764
| 2mg | 41.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 402.00 € | ||
| 200mg | 570.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
Y-27632
CAS:146986-50-7
Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.
Formula:
C14H21N3O
Purity:
99.53% - 99.87%
Color and Shape:
Solid
Molecular weight:
247.34
Ref: TM-T1870
| 5mg | 46.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 167.00 € | ||
| 100mg | 270.00 € | ||
| 200mg | 420.00 € | ||
| 500mg | 693.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 25 Feb 2025
