HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 180 products of "HSP"
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Apoptozole
CAS:Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.Formula:C33H25F6N3O3Purity:99.75%Color and Shape:SolidMolecular weight:625.56Ref: TM-T3293
2mg34.00€5mg48.00€10mg79.00€25mg130.00€50mg222.00€100mg331.00€200mg489.00€1mL*10mM (DMSO)63.00€DTHIB
CAS:DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.Formula:C13H9ClFN3O3Purity:98.86% - 99.29%Color and Shape:SolidMolecular weight:309.68Ref: TM-T8858
1mg34.00€5mg66.00€10mg99.00€25mg200.00€50mg319.00€100mg512.00€500mg1,071.00€1mL*10mM (DMSO)73.00€KNK437
CAS:KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).Formula:C13H11NO4Purity:98.90%Color and Shape:SolidMolecular weight:245.23Ref: TM-T2444
2mg38.00€5mg54.00€10mg77.00€25mg149.00€50mg220.00€100mg331.00€200mg530.00€1mL*10mM (DMSO)59.00€MitoBloCK-10
CAS:MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.Formula:C12H8FN3O3SPurity:99.51%Color and Shape:SolidMolecular weight:293.27Ref: TM-T8741
1mg66.00€5mg144.00€10mg205.00€25mg349.00€50mg500.00€100mg700.00€200mg954.00€500µg46.00€1mL*10mM (DMSO)136.00€Tanespimycin
CAS:Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!Formula:C31H43N3O8Purity:98.24% - 99.83%Color and Shape:Dark Purple SolidMolecular weight:585.69MK2-IN-1
CAS:MK2-IN-1 is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode.Formula:C27H25ClN4O2Color and Shape:SolidMolecular weight:472.97Palmitic acid
CAS:Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.Formula:C16H32O2Purity:99.17% - 99.67%Color and Shape:White Crystalline Scales SolidMolecular weight:256.42Pimitespib
CAS:Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).Formula:C25H26N8OPurity:99.22% - 99.49%Color and Shape:SolidMolecular weight:454.53VER-155008
CAS:VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.
Formula:C25H23Cl2N7O4Purity:97.03% - 99.55%Color and Shape:SolidMolecular weight:556.4HSP70-IN-1
CAS:HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).
Formula:C24H28N6O2SPurity:99.91%Color and Shape:SolidMolecular weight:464.58HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Formula:C23H22N4O3S2Purity:99.77% - 99.86%Color and Shape:SolidMolecular weight:466.58Ref: TM-T6855
1mg35.00€2mg48.00€5mg72.00€10mg96.00€25mg187.00€50mg283.00€100mg439.00€1mL*10mM (DMSO)74.00€Feretoside
CAS:Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).Formula:C17H24O11Purity:99.85%Color and Shape:SolidMolecular weight:404.37Ref: TM-TQ0280
1mg73.00€5mg167.00€10mg260.00€25mg440.00€50mg628.00€100mg872.00€200mg1,153.00€1mL*10mM (DMSO)190.00€HSP27 inhibitor J2
CAS:HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function ofFormula:C13H12O4SPurity:99.51%Color and Shape:SolidMolecular weight:264.3Ref: TM-T7265
1mg123.00€2mg175.00€5mg295.00€10mg447.00€25mg713.00€50mg1,009.00€100mg1,341.00€1mL*10mM (DMSO)432.00€PU-H54
CAS:PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.Formula:C18H19N5SPurity:99.13%Color and Shape:SolidMolecular weight:337.44Geldanamycin
CAS:Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.Formula:C29H40N2O9Purity:97.59% - 99.27%Color and Shape:Yellow To Orange PowderMolecular weight:560.64KBU2046
CAS:KBU2046: oral anti-metastasis compound, enhances survival, targets chaperone complexes, not a typical HSP90 inhibitor.Formula:C15H11FO2Purity:99.89%Color and Shape:SolidMolecular weight:242.24Ref: TM-T15646
2mg33.00€5mg50.00€10mg71.00€25mg133.00€50mg200.00€100mg304.00€200mg425.00€1mL*10mM (DMSO)50.00€HM03
CAS:HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.Formula:C26H27ClN4O2Purity:97.15%Color and Shape:SolidMolecular weight:462.972-hexyl-4-Pentynoic Acid
CAS:2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.Formula:C11H18O2Purity:98%Color and Shape:SolidMolecular weight:182.26Luminespib
CAS:Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.
Formula:C26H31N3O5Purity:98% - 99.25%Color and Shape:SolidMolecular weight:465.54Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Formula:C24H31N3O3Purity:99.01% - 99.66%Color and Shape:SolidMolecular weight:409.52
