Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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PARP Protein, Mouse, Recombinant (His)
<p>PARP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.</p>Color and Shape:Lyophilized PowderMolecular weight:115 kDa (predicted); 75 kDa (reducing conditions)N-Descyclopropanecarbaldehyde Olaparib
CAS:<p>N-Descyclopropanecarbaldehyde Olaparib is a CRBN ligand for dual EGFR/PARP PROTAC, suitable for F-18 radiolabeling and tumor imaging via PET.</p>Formula:C20H19FN4O2Color and Shape:SolidMolecular weight:366.39PROTAC EZH2 Degrader-1
CAS:<p>PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.</p>Formula:C54H67N7O8Color and Shape:SolidMolecular weight:942.15PARP1 Protein, Human, Recombinant (His)
<p>PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.</p>Purity:94.1%Color and Shape:Lyophilized PowderMolecular weight:114.5 kDa (predicted); 100-110 kDa (reducing conditions)MI-3454
CAS:<p>MI-3454: potent, oral menin-MLL1 inhibitor, IC50 of 0.51 nM, halts leukemia cells, aids remission in mice.</p>Formula:C32H35F3N8OSPurity:99.68%Color and Shape:SolidMolecular weight:636.73INO-1001
CAS:<p>INO-1001: potent PARP inhibitor with antitumor properties, enhances radiosensitivity & radiation-induced cell death.</p>Formula:C23H25N3O4SColor and Shape:SolidMolecular weight:439.53Itacitinib adipate
CAS:<p>Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.</p>Formula:C32H33F4N9O5Color and Shape:SolidMolecular weight:699.66Boc-Lys(Ac)-AMC
CAS:<p>Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).</p>Formula:C23H31N3O6Purity:99.87%Color and Shape:SolidMolecular weight:445.51PROTAC PARP1 degrader
CAS:<p>PROTAC PARP1 degrader suppresses MDA-MB-231 cells at 10 μM, IC50: 6.12 μM in 24h.</p>Formula:C58H63Cl2N11O10Purity:98%Color and Shape:SolidMolecular weight:1145.1MC4171
<p>MC4171 is a selective KAT8 inhibitor with antiproliferative activity and can be used to study cancer.</p>Formula:C21H15N3O3Purity:99.56%Color and Shape:SolidMolecular weight:357.36PR5-LL-CM01
CAS:<p>PR5-LL-CM01 is a novel protein arginine methyltransferase 5 (PRMT5) inhibitor in colorectal and pancreatic cancers.</p>Formula:C23H27N7Color and Shape:SolidMolecular weight:401.51JET-209
<p>JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) values</p>Formula:C46H47N9O6Purity:98%Color and Shape:SolidMolecular weight:821.92DTP3
CAS:<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Formula:C26H35N7O5Color and Shape:SolidMolecular weight:525.6TPOP146
CAS:<p>TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).</p>Formula:C27H35N3O5Purity:98%Color and Shape:SolidMolecular weight:481.58KDM4C-IN-1
CAS:<p>KDM4C-IN-1 is aKDM4C inhibitor withial anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.</p>Formula:C15H14N4O3Purity:99.33%Color and Shape:SolidMolecular weight:298.3Atinvicitinib
CAS:<p>Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.</p>Formula:C16H17FN6O3Purity:99.36%Color and Shape:SolidMolecular weight:360.35GSK2879552
CAS:<p>GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.</p>Formula:C23H28N2O2Purity:99.22%Color and Shape:SolidMolecular weight:364.48SGC-iMLLT
CAS:<p>SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular target</p>Formula:C22H24N6OPurity:99.21%Color and Shape:SolidMolecular weight:388.47AZ505 ditrifluoroacetate
CAS:<p>AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).</p>Formula:C33H40Cl2F6N4O8Color and Shape:SolidMolecular weight:805.59GSK778
CAS:<p>GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.</p>Formula:C30H33N5O3Purity:98.42%Color and Shape:SolidMolecular weight:511.61TH1834
CAS:<p>TH1834 is a specific inhibitor of Tip60/KAT5 histone acetyltransferase. TH1834 induces apoptosis and DNA damage in MCF.</p>Formula:C33H40N6O3Purity:99.96%Color and Shape:SolidMolecular weight:568.71Pim-1/2 kinase inhibitor 1
CAS:<p>Orally active Pim-1/2 inhibitor blocks kinase phosphorylation; used in prostate cancer research.</p>Formula:C11H9NO3SPurity:99.78%Color and Shape:SolidMolecular weight:235.26(2R)-Octyl-α-hydroxyglutarate
CAS:<p>(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.</p>Formula:C13H24O5Color and Shape:SolidMolecular weight:260.33GSK-J2
CAS:<p>GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.</p>Formula:C22H23N5O2Purity:97.55%Color and Shape:SolidMolecular weight:389.452'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS:<p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>Formula:C9H13ClFN3O4Purity:99.69%Color and Shape:SolidMolecular weight:281.67MS8511 hydrochloride
CAS:<p>MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics.</p>Formula:C28H42ClN5O3Color and Shape:SolidMolecular weight:532.12CHZ868
CAS:<p>CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.</p>Formula:C22H19F2N5O2Purity:99.38%Color and Shape:SolidMolecular weight:423.42GSK9311
CAS:<p>GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).</p>Formula:C24H31N5O3Purity:98%Color and Shape:SolidMolecular weight:437.53ADTL-SA1215
CAS:<p>ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.</p>Formula:C26H29I2NO3Purity:99.23%Color and Shape:SolidMolecular weight:657.32EHMT2-IN-1
CAS:<p>EHMT2-IN-1: potent EHMT inhibitor, for blood disorders/cancer research; IC50s <100 nM for EHMT1/2 peptides and cellular EHMT2.</p>Formula:C18H23N7OColor and Shape:SolidMolecular weight:353.42O6BTG-octylglucoside
CAS:<p>O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).</p>Formula:C24H34BrN5O7SPurity:98%Color and Shape:SolidMolecular weight:616.53(±)-1,2-Diolein
CAS:<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Formula:C39H72O5Color and Shape:SolidMolecular weight:620.99Fenbendazole-d3
CAS:<p>Fenbendazole-d3 is a deuterated compound of Fenbendazole. Fenbendazole has a CAS number of 43210-67-9. Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.</p>Formula:C15H10D3N3O2SColor and Shape:SolidMolecular weight:302.37CX-6258 hydrochloride hydrate
CAS:<p>CX-6258 hydrochloride hydrate is a potent and selective inhibitor of pan-Pim kinase that acts on Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM) and Pim-3 (IC50: 16 nM</p>Formula:C26H27Cl2N3O4Color and Shape:SolidMolecular weight:516.42(R)-GSK-3685032
CAS:<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Formula:C22H24N6OSColor and Shape:SolidMolecular weight:420.54BAY-850
CAS:<p>BAY-850 is ainhibitor of adenosine triphosphatase family protein 2 that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.</p>Formula:C38H44ClN5O3Purity:98% - 98%Color and Shape:SolidMolecular weight:654.24DA-3003-1
CAS:<p>DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.</p>Formula:C15H16ClN3O3Purity:99.27% - 99.79%Color and Shape:SolidMolecular weight:321.76Ilunocitinib
CAS:<p>Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.</p>Formula:C17H17N7O2SPurity:99.88%Color and Shape:SolidMolecular weight:383.43NSC 694621
CAS:<p>NSC 694621 is a PCAF inhibitor that forms a covalent bond with Cys574, irreversibly inhibiting its acetyltransferase activity, inhibit proliferation,anticancer.</p>Formula:C13H10N2O2SPurity:99.7%Color and Shape:SolidMolecular weight:258.3Anti-PARP1 Antibody (8I163)
<p>Anti-PARP1 Antibody (8I163) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (8I163) can be used in IHC-P.</p>Color and Shape:Odour LiquidAnti-PARP Antibody (1W26)
<p>Anti-PARP Antibody (1W26) is a Mouse antibody targeting PARP. Anti-PARP Antibody (1W26) can be used in WB,IHC-P,IP.</p>Color and Shape:Odour LiquidAnti-PARP1 Antibody (6I459)
<p>Anti-PARP1 Antibody (6I459) is an antibody targeting PARP1. Anti-PARP1 Antibody (6I459) can be used in ELISA, IHC.</p>Color and Shape:Odour LiquidAnti-PARP1 Antibody (7A800)
<p>Anti-PARP1 Antibody (7A800) is an antibody targeting PARP1. Anti-PARP1 Antibody (7A800) can be used in ELISA, WB, IHC.</p>Color and Shape:Odour LiquidAnti-PARP1 Antibody (9E313)
<p>Anti-PARP1 Antibody (9E313) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (9E313) can be used in IHC-P.</p>Color and Shape:Odour LiquidAnti-PARP1 Antibody (8S756)
<p>Anti-PARP1 Antibody (8S756) is an antibody targeting PARP1. Anti-PARP1 Antibody (8S756) can be used in ELISA, WB, IHC, IF, FCM.</p>Color and Shape:Odour LiquidGintemetostat
CAS:<p>Gintemetostat (KTX-1001) is a potent NSD2 inhibitor (IC50=0.001-0.01μM) for treating NSD2-dysregulated cancers.</p>Formula:C25H26F4N8O2Color and Shape:SolidMolecular weight:546.521,4-DPCA ethyl ester
CAS:<p>1,4-DPCA ethyl ester is a form of 1,4-DPCA modified, which has potential anticancer activity based on growth inhibition assays with the mlh1 rad18 yeast strain.</p>Formula:C15H12N2O3Purity:99.54%Color and Shape:SolidMolecular weight:268.277-Chloro-4-(piperazin-1-yl)quinoline
CAS:<p>7-Cl-4-(piperazin-1-yl)quinolone: sirtuin inhibitor, serotonin uptake blocker, antimalarial (D10 IC50 1.18µM, K1 IC50 0.97µM).</p>Formula:C13H14ClN3Purity:99.52%Color and Shape:Light Yellow SolidMolecular weight:247.72KDM4-IN-3
CAS:<p>KDM4-IN-3 is a KDM4 inhibitor that is cell-permeable and kills prostate cancer cells at low micromolar concentrations.</p>Formula:C17H14N4OColor and Shape:SolidMolecular weight:290.32AMI-1 free acid
CAS:<p>AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.</p>Formula:C21H16N2O9S2Purity:97.8%Color and Shape:SolidMolecular weight:504.49PCAF-IN-1
CAS:<p>PCAF-IN-1 is a highly selective PCAF inhibitor with potential anti-tumor, anti-inflammatory, and anti-heart disease effects.</p>Formula:C15H11ClN6Color and Shape:SolidMolecular weight:310.74TCS PIM-1 1
CAS:<p>TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.</p>Formula:C18H11BrN2O2Purity:97% - 97.98%Color and Shape:SolidMolecular weight:367.2BI-7273
CAS:<p>BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.</p>Formula:C20H23N3O3Purity:97.37% - 99.57%Color and Shape:SolidMolecular weight:353.41BIX-01294
CAS:<p>BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).</p>Formula:C28H38N6O2Purity:98.58% - 99.64%Color and Shape:SolidMolecular weight:490.64PI-1840
CAS:<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.473-methyl-1,2-dihydroquinolin-2-one
CAS:<p>3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.</p>Formula:C10H9NOPurity:99.62%Color and Shape:SolidMolecular weight:159.18Ritlecitinib
CAS:<p>Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.</p>Formula:C15H19N5OPurity:98.82% - 99.92%Color and Shape:SolidMolecular weight:285.34Remodelin hydrobromide
CAS:<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Formula:C15H15BrN4SPurity:97.22% - 99.84%Color and Shape:SolidMolecular weight:363.275BD750
CAS:<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Formula:C14H13N3OSPurity:99.02%Color and Shape:SolidMolecular weight:271.342,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:SolidMolecular weight:350.2Senaparib
CAS:<p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>Formula:C24H20F2N6O3Purity:99.8%Color and Shape:SolidMolecular weight:478.45JQ-1 (carboxylic acid)
CAS:<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Formula:C19H17ClN4O2SPurity:99.14% - 99.9%Color and Shape:SolidMolecular weight:400.88Aurora kinase inhibitor-3
CAS:<p>Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,</p>Formula:C21H18F3N5OPurity:98.91%Color and Shape:SolidMolecular weight:413.4NSC 228155
CAS:<p>NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.</p>Formula:C11H6N4O4SPurity:99.84%Color and Shape:SolidMolecular weight:290.25PF-CBP1
CAS:<p>PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).</p>Formula:C29H36N4O3Purity:99.45%Color and Shape:SolidMolecular weight:488.62TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Formula:C31H31ClFN7O2Purity:98.49% - 99.62%Color and Shape:SolidMolecular weight:588.07653-47
CAS:<p>653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).</p>Formula:C20H19ClN2O3Color and Shape:SolidMolecular weight:370.83PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48Pyridone 6
CAS:<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Formula:C18H16FN3OPurity:97.1% - 98.74%Color and Shape:SolidMolecular weight:309.34Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.346-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:<p>CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).</p>Formula:C9H9BrN2OPurity:99.28%Color and Shape:SolidMolecular weight:241.081,5-Isoquinolinediol
CAS:<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formula:C9H7NO2Purity:98.29% - 99.35%Color and Shape:Of White To White PowderMolecular weight:161.16UNC1079
CAS:<p>UNC1079 is an selective L3MBTL3 domain inhibitor</p>Formula:C28H42N4O2Purity:99.48%Color and Shape:SolidMolecular weight:466.66666-15
CAS:<p>666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.</p>Formula:C33H31Cl2N3O5Purity:99.41% - 99.88%Color and Shape:SolidMolecular weight:620.52WHI-P97
CAS:<p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.1EPZ015666
CAS:<p>EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity.</p>Formula:C20H25N5O3Purity:98% - 99.64%Color and Shape:SolidMolecular weight:383.44BI-9564
CAS:<p>BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.</p>Formula:C20H23N3O3Purity:99.38%Color and Shape:SolidMolecular weight:353.41GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Formula:C18H15N3O2Purity:99.52%Color and Shape:SolidMolecular weight:305.33KDM4D-IN-1
CAS:<p>KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).</p>Formula:C11H7N5OPurity:99.51% - >99.99%Color and Shape:SolidMolecular weight:225.21LLY-507
CAS:<p>LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.</p>Formula:C36H42N6OPurity:99.58% - 99.93%Color and Shape:SolidMolecular weight:574.764-amino-1,8-Naphthalimide
CAS:<p>4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM</p>Formula:C12H8N2O2Purity:95.13%Color and Shape:Yellow Solid PowderMolecular weight:212.23,6-Dihydroxyflavone
CAS:<p>3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.</p>Formula:C15H10O4Purity:99.92%Color and Shape:SolidMolecular weight:254.24Piribedil hydrochloride
CAS:<p>Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.</p>Formula:C16H19ClN4O2Color and Shape:SolidMolecular weight:334.8ML324
CAS:<p>ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).</p>Formula:C21H23N3O2Purity:98.22% - 98.57%Color and Shape:SolidMolecular weight:349.43Upadacitinib
CAS:<p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>Formula:C17H19F3N6OPurity:98.96% - 99.94%Color and Shape:SolidMolecular weight:380.37PFI-2 hydrochloride
CAS:<p>PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),</p>Formula:C23H26ClF4N3O3SPurity:99.31% - 99.91%Color and Shape:SolidMolecular weight:535.98BMS-P5 free base
CAS:<p>BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.</p>Formula:C27H32N6O2Purity:99.88%Color and Shape:SolidMolecular weight:472.58Niraparib tosylate monohyrate
CAS:<p>Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.</p>Formula:C26H30N4O5SPurity:97.7% - 98.41%Color and Shape:SolidMolecular weight:510.614'-Methoxychalcone
CAS:<p>4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.</p>Formula:C16H14O2Purity:99.86%Color and Shape:SolidMolecular weight:238.28BAY 87-2243
CAS:<p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>Formula:C26H26F3N7O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:525.53HNHA
CAS:<p>HNHA is an inhibitor of HDAC.</p>Formula:C17H21NO2SPurity:98.04%Color and Shape:SolidMolecular weight:303.42Amodiaquine hydrochloride
CAS:<p>Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.</p>Formula:C20H24Cl3N3OColor and Shape:SolidMolecular weight:428.78CPI-637
CAS:<p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>Formula:C22H22N6OPurity:99.89% - 99.95%Color and Shape:SolidMolecular weight:386.45TIQ-A
CAS:<p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>Formula:C11H7NOSPurity:99.75%Color and Shape:SolidMolecular weight:201.24GSK-J4 Hydrochloride
CAS:<p>GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.</p>Formula:C24H28ClN5O2Purity:97.95% - 98.23%Color and Shape:SolidMolecular weight:453.97FG-2216
CAS:<p>FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.</p>Formula:C12H9ClN2O4Purity:97.1% - >99.99%Color and Shape:SolidMolecular weight:280.66PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44Nudifloramide
CAS:<p>Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).</p>Formula:C7H8N2O2Purity:99.7% - ≥95%Color and Shape:SolidMolecular weight:152.15TG101209
CAS:<p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>Formula:C26H35N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:509.67
