Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2612 products of "Chromatin/Epigenetics"
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Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:SolidMolecular weight:438.48Ref: TM-T6278
1mg44.00€5mg86.00€10mg135.00€25mg254.00€50mg423.00€100mg605.00€200mg845.00€1mL*10mM (DMSO)94.00€AK-7
CAS:AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.Formula:C19H21BrN2O3SPurity:98.43% - 99.34%Color and Shape:SolidMolecular weight:437.35Ref: TM-T5490
1mg34.00€2mg47.00€5mg71.00€10mg100.00€25mg177.00€50mg313.00€100mg512.00€1mL*10mM (DMSO)89.00€PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.Formula:C78H132N30O18Purity:98.78%Color and Shape:SolidMolecular weight:1778.10Picolinamide
CAS:Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.Formula:C6H6N2OPurity:99.6%Color and Shape:SolidMolecular weight:122.12MS049
CAS:MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Formula:C15H24N2OPurity:98.91%Color and Shape:SolidMolecular weight:248.36Ref: TM-T4378
2mg34.00€5mg49.00€10mg80.00€25mg149.00€50mg222.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)52.00€TCS-PIM-1-4a
CAS:SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formula:C11H6F3NO2SPurity:99.89%Color and Shape:SolidMolecular weight:273.23PTACH
CAS:PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).Formula:C20H26N2O2S2Purity:87.44% - 99.74%Color and Shape:SolidMolecular weight:390.56MS023
CAS:MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,Formula:C17H25N3OPurity:98.31% - 99.87%Color and Shape:SolidMolecular weight:287.4Ref: TM-T6900
1mg37.00€2mg49.00€5mg84.00€10mg113.00€25mg230.00€50mg358.00€100mg532.00€500mg1,153.00€1mL*10mM (DMSO)79.00€E1231
CAS:E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.Formula:C21H21N3O3Purity:98.45%Color and Shape:SolidMolecular weight:363.41Ref: TM-T9106
1mg34.00€5mg70.00€10mg99.00€25mg195.00€50mg311.00€100mg449.00€500mg888.00€1mL*10mM (DMSO)94.00€R59949
CAS:R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Formula:C28H25F2N3OSPurity:97.04%Color and Shape:SolidMolecular weight:489.58Ref: TM-T26019
1mg39.00€2mg52.00€5mg87.00€10mg138.00€25mg281.00€50mg425.00€100mg625.00€200mg883.00€1mL*10mM (DMSO)95.00€EDO-S101
CAS:EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.Formula:C19H28Cl2N4O2Purity:98.02% - 99.44%Color and Shape:SolidMolecular weight:415.36ACY-738
CAS:ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.Formula:C14H14N4O2Purity:98.85% - 99.89%Color and Shape:SolidMolecular weight:270.29Ref: TM-T3509
1mg46.00€2mg62.00€5mg90.00€10mg165.00€25mg268.00€50mg439.00€100mg582.00€1mL*10mM (DMSO)100.00€CAY10602
CAS:CAY10602 activates SIRT1, suppresses NF-κB/TNF-α in THP-1 cells with 75% efficacy at 60 μM, non-toxic.Formula:C22H15FN4O2SPurity:98.92%Color and Shape:SolidMolecular weight:418.44SKLB-23bb
CAS:SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability.Formula:C21H24N4O4Purity:97.58%Color and Shape:SolidMolecular weight:396.44Ref: TM-T5830
1mg50.00€5mg133.00€10mg187.00€25mg304.00€50mg424.00€100mg587.00€200mg800.00€1mL*10mM (DMSO)147.00€GSK121
CAS:GSK121 is an inhibitor of selective PAD4.
Formula:C25H26F3N5O3Purity:98.92%Color and Shape:SolidMolecular weight:501.51PJ34
CAS:PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
Formula:C17H17N3O2Purity:95.05% - 99.85%Color and Shape:SolidMolecular weight:295.34TH34
CAS:TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.Formula:C15H16N2O2Purity:98.32%Color and Shape:SolidMolecular weight:256.3HIF-2α-IN-4
CAS:HIF-2a translation inhibitor is a compound used as a molecular building block.Formula:C9H9N3O4S2Purity:≥98%Color and Shape:SolidMolecular weight:287.32Ref: TM-T50099
5mg37.00€10mg60.00€25mg111.00€50mg200.00€100mg299.00€200mg430.00€1mL*10mM (DMSO)44.00€SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formula:C25H20FN7OPurity:97.82%Color and Shape:SolidMolecular weight:453.47Ref: TM-T8685
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)177.00€SirReal2
CAS:SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.Formula:C22H20N4OS2Purity:99.52% - 99.75%Color and Shape:SolidMolecular weight:420.55Ref: TM-T6984
1mg37.00€2mg52.00€5mg74.00€10mg102.00€25mg187.00€50mg295.00€100mg477.00€1mL*10mM (DMSO)86.00€
