Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2597 products of "Chromatin/Epigenetics"
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A-366
CAS:A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.Formula:C19H27N3O2Purity:97.28% - 99.8%Color and Shape:SolidMolecular weight:329.44Ref: TM-T3624
1mg35.00€2mg50.00€5mg74.00€10mg90.00€25mg208.00€50mg359.00€100mg530.00€1mL*10mM (DMSO)82.00€UNC3866 TFA(1872382-47-2 free base)
CAS:UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Formula:C45H67F3N6O10Purity:98.43%Color and Shape:SolidMolecular weight:909.046-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurity:98.75% - >99.99%Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline PowderMolecular weight:167.19IOX4
CAS:IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)Formula:C15H16N6O3Purity:99.97%Color and Shape:SolidMolecular weight:328.33NEO2734
CAS:NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).Formula:C22H24F3N3O3Purity:98.72% - 98.8%Color and Shape:SolidMolecular weight:435.44Ref: TM-T8658
1mg108.00€5mg260.00€10mg430.00€25mg710.00€50mg973.00€100mg1,333.00€500mg2,673.00€1mL*10mM (DMSO)286.00€Panaxadiol
CAS:Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Formula:C30H52O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:460.73XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ref: TM-T17267
1mg52.00€2mg73.00€5mg94.00€10mg141.00€25mg244.00€50mg371.00€100mg552.00€1mL*10mM (DMSO)104.00€Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.591-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS:1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).Formula:C17H19NOPurity:99.08%Color and Shape:SolidMolecular weight:253.34Ref: TM-T8601
1mg62.00€5mg123.00€10mg180.00€25mg298.00€50mg419.00€100mg567.00€200mg752.00€1mL*10mM (DMSO)115.00€GSK620
CAS:GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.Formula:C18H19N3O3Purity:99.42% - 99.88%Color and Shape:SolidMolecular weight:325.36Ref: TM-T9020
2mg34.00€5mg49.00€10mg73.00€25mg136.00€50mg212.00€100mg314.00€200mg467.00€1mL*10mM (DMSO)87.00€Talazoparib
CAS:Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).Formula:C19H14F2N6OPurity:97.02% - 99.92%Color and Shape:SolidMolecular weight:380.35Ref: TM-T6253
2mg42.00€5mg62.00€10mg88.00€25mg135.00€50mg187.00€100mg311.00€200mg429.00€500mg697.00€1mL*10mM (DMSO)67.00€Solcitinib
CAS:Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.
Formula:C22H23N5O2Purity:99.61% - 99.82%Color and Shape:SolidMolecular weight:389.45Dbet57
CAS:dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.Formula:C34H31ClN8O5SPurity:99.36% - 99.52%Color and Shape:SolidMolecular weight:699.18Ref: TM-T5440
1mg47.00€5mg92.00€10mg147.00€25mg264.00€50mg409.00€100mg592.00€500mg1,224.00€1mL*10mM (DMSO)166.00€MAT2A inhibitor 4
CAS:MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancerFormula:C16H15ClFNPurity:99.17%Color and Shape:SolidMolecular weight:275.75Ref: TM-T9262
1mg40.00€5mg90.00€10mg131.00€25mg220.00€50mg314.00€100mg426.00€200mg575.00€1mL*10mM (DMSO)89.00€Mivebresib
CAS:Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.Formula:C22H19F2N3O4SPurity:98.74% - 99.32%Color and Shape:SolidMolecular weight:459.47Ref: TM-T3712
1mg55.00€2mg78.00€5mg92.00€10mg150.00€25mg244.00€50mg437.00€100mg625.00€1mL*10mM (DMSO)94.00€PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formula:C28H35N7O2Purity:98.2%Color and Shape:SolidMolecular weight:501.623-Aminobenzamide
CAS:3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction duringFormula:C7H8N2OPurity:98.4% - 99.5%Color and Shape:White To Off-White PowderMolecular weight:136.15SF2523
CAS:SF2523 is a highly selective and potent inhibitor.Formula:C19H17NO5SPurity:99.1% - 99.51%Color and Shape:SolidMolecular weight:371.41Ref: TM-T3986
1mg34.00€5mg74.00€10mg113.00€25mg260.00€50mg409.00€100mg605.00€500mg1,288.00€1mL*10mM (DMSO)82.00€JNJ-64619178
CAS:JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.Formula:C22H23BrN6O2Purity:98.86% - 99.98%Color and Shape:SolidMolecular weight:483.36Ref: TM-T15624
1mg84.00€5mg167.00€10mg260.00€25mg537.00€50mg893.00€100mg1,571.00€1mL*10mM (DMSO)172.00€GeA-69
CAS:GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).Formula:C20H16N2OPurity:99.85%Color and Shape:SolidMolecular weight:300.35
