Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2612 products of "Chromatin/Epigenetics"
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Ritlecitinib
CAS:Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.Formula:C15H19N5OPurity:98.82% - 99.92%Color and Shape:SolidMolecular weight:285.34Ref: TM-T5382
2mg37.00€5mg52.00€10mg90.00€25mg205.00€50mg290.00€100mg408.00€200mg595.00€1mL*10mM (DMSO)73.00€6-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).Formula:C9H9BrN2OPurity:99.28%Color and Shape:SolidMolecular weight:241.08Ref: TM-T8609
1mg58.00€5mg116.00€10mg172.00€25mg281.00€50mg396.00€100mg537.00€200mg712.00€1mL*10mM (DMSO)107.00€WZ4003
CAS:WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formula:C25H29ClN6O3Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:496.99Ref: TM-T6291
5mg48.00€10mg73.00€25mg111.00€50mg166.00€100mg241.00€200mg358.00€500mg590.00€1mL*10mM (DMSO)50.00€I-CBP112
CAS:I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.Formula:C27H36N2O5Purity:98.18%Color and Shape:SolidMolecular weight:468.59Ref: TM-T3969
1mg33.00€2mg50.00€5mg92.00€10mg161.00€25mg296.00€50mg425.00€100mg583.00€200mg785.00€1mL*10mM (DMSO)92.00€Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18Amifostine sodium
CAS:Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formula:C5H15N2NaO3PSColor and Shape:SolidMolecular weight:237.21CM-579 trihydrochloride
CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.Formula:C29H43Cl3N4O3Color and Shape:SolidMolecular weight:602.04NU1025
CAS:NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.Formula:C9H8N2O2Purity:99.86%Color and Shape:SolidMolecular weight:176.17Ref: TM-T6912
2mg46.00€5mg67.00€10mg98.00€25mg178.00€50mg301.00€100mg475.00€500mg1,063.00€1mL*10mM (DMSO)67.00€ZINC13466751
CAS:ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 µM).Formula:C20H21N5O2Purity:99.8%Color and Shape:SolidMolecular weight:363.41UNC1079
CAS:UNC1079 is an selective L3MBTL3 domain inhibitor
Formula:C28H42N4O2Purity:99.48%Color and Shape:SolidMolecular weight:466.66Senaparib
CAS:Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.Formula:C24H20F2N6O3Purity:99.8%Color and Shape:SolidMolecular weight:478.45Ref: TM-T9593
1mg46.00€2mg59.00€5mg87.00€10mg153.00€25mg274.00€50mg432.00€100mg638.00€1mL*10mM (DMSO)96.00€A-769662
CAS:A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).Formula:C20H12N2O3SPurity:97.52% - 99.58%Color and Shape:SolidMolecular weight:360.39Ref: TM-T2468
2mg37.00€5mg54.00€10mg74.00€25mg135.00€50mg244.00€100mg440.00€500mg964.00€1mL*10mM (DMSO)56.00€BAZ1A-IN-1
CAS:BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.Formula:C16H12N4O3SPurity:99.87%Color and Shape:SolidMolecular weight:340.36Ref: TM-T9552
1mg84.00€5mg177.00€10mg268.00€25mg537.00€50mg803.00€100mg1,099.00€200mg1,468.00€1mL*10mM (DMSO)195.00€A1874
CAS:A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.
Formula:C58H62Cl3F2N9O7SPurity:99.52%Color and Shape:SolidMolecular weight:1173.59M1001
CAS:M1001 is a HIF-2α agonist.Formula:C17H17N3O2SPurity:98.83%Color and Shape:SolidMolecular weight:327.4Cucurbitacin I
CAS:Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.Formula:C30H42O7Purity:96.69% - 99.8%Color and Shape:SolidMolecular weight:514.65KDM4D-IN-1
CAS:KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).Formula:C11H7N5OPurity:99.51% - >99.99%Color and Shape:SolidMolecular weight:225.21Ref: TM-T4214
1mg73.00€5mg158.00€10mg245.00€25mg495.00€50mg795.00€100mg1,161.00€1mL*10mM (DMSO)168.00€JNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formula:C15H12F2N6O3SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:394.36Ref: TM-T6126
1mg48.00€5mg100.00€10mg155.00€25mg268.00€50mg432.00€100mg595.00€200mg833.00€1mL*10mM (DMSO)94.00€MR837
CAS:MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.Formula:C16H14N2OSPurity:99.77% - 99.85%Color and Shape:SolidMolecular weight:282.36Ref: TM-T8879
2mg38.00€5mg55.00€10mg92.00€25mg138.00€50mg243.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)66.00€Apabetalone
CAS:Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary arteryFormula:C20H22N2O5Purity:98.08% - ≥98%Color and Shape:SolidMolecular weight:370.4PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48BRD4 Inhibitor-24
CAS:BRD4 Inhibitor-24 is a BRD4 small molecule inhibitor with antitumor activity.Formula:C13H14N2O4Purity:99.66%Color and Shape:SolidMolecular weight:262.26BI-9564
CAS:BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.
Formula:C20H23N3O3Purity:99.38%Color and Shape:SolidMolecular weight:353.41EPZ015666
CAS:EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity.Formula:C20H25N5O3Purity:98% - 99.64%Color and Shape:SolidMolecular weight:383.44CPI-455
CAS:CPI-455 is a specific KDM5 inhibitor.Formula:C16H14N4OPurity:97.87% - 99.03%Color and Shape:SolidMolecular weight:278.31Ref: TM-T3552
1mg34.00€2mg49.00€5mg70.00€10mg105.00€25mg178.00€50mg335.00€100mg505.00€1mL*10mM (DMSO)70.00€MK-8617
CAS:MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).Formula:C24H21N5O4Purity:99.38% - >99.99%Color and Shape:SolidMolecular weight:443.45MI-463
CAS:MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).Formula:C24H23F3N6SPurity:99.18% - >99.99%Color and Shape:SolidMolecular weight:484.54ASP4132
CAS:ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Formula:C46H51F3N6O8S2Purity:98.34%Color and Shape:SolidMolecular weight:937.06Ref: TM-T8432
1mg50.00€5mg114.00€10mg177.00€25mg321.00€50mg482.00€100mg677.00€200mg928.00€1mL*10mM (DMSO)185.00€LLY-507
CAS:LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.Formula:C36H42N6OPurity:99.58% - 99.93%Color and Shape:SolidMolecular weight:574.76Ref: TM-T6879
1mg42.00€2mg52.00€5mg80.00€10mg131.00€25mg289.00€50mg522.00€100mg747.00€1mL*10mM (DMSO)104.00€PF-06409577
CAS:PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Formula:C19H16ClNO3Purity:95.17% - 98.21%Color and Shape:SolidMolecular weight:341.79Ref: TM-T4427
1mg34.00€2mg43.00€5mg63.00€10mg100.00€25mg200.00€50mg334.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)71.00€Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formula:C18H24N6O2Color and Shape:SolidMolecular weight:356.433,6-Dihydroxyflavone
CAS:3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Formula:C15H10O4Purity:99.92%Color and Shape:SolidMolecular weight:254.24SETDB1-TTD-IN-1 TFA
SETDB1-TTD-IN-1 TFA: potent, selective SETDB1-TTD inhibitor (Kd: 88 nM), useful for related biological research.Formula:C30H32F3N5O4Color and Shape:SolidMolecular weight:583.6Piribedil hydrochloride
CAS:Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.Formula:C16H19ClN4O2Color and Shape:SolidMolecular weight:334.8ML324
CAS:ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).Formula:C21H23N3O2Purity:98.22% - 98.57%Color and Shape:SolidMolecular weight:349.43Ref: TM-T6593
2mg34.00€5mg49.00€10mg74.00€25mg122.00€50mg205.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)79.00€PFI-2 hydrochloride
CAS:PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formula:C23H26ClF4N3O3SPurity:99.31% - 99.91%Color and Shape:SolidMolecular weight:535.98Ref: TM-T4583
1mg38.00€2mg49.00€5mg80.00€10mg111.00€25mg200.00€50mg358.00€100mg523.00€500mg1,108.00€1mL*10mM (DMSO)122.00€Fucosterol
CAS:Fucosterol, from E. stolonifera, has anti-diabetic, anti-adipogenic, anti-cancer properties; it affects PPARα and C/EBPα to control fat cell formation.Formula:C29H48OPurity:98% - 99.68%Color and Shape:White PowderMolecular weight:412.69BEBT-908
CAS:BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Formula:C23H25N9O3SPurity:99.67%Color and Shape:SolidMolecular weight:507.57Ref: TM-T16529
1mg94.00€5mg222.00€10mg334.00€25mg562.00€50mg802.00€100mg1,063.00€200mg1,459.00€1mL*10mM (DMSO)249.00€4-amino-1,8-Naphthalimide
CAS:4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nMFormula:C12H8N2O2Purity:95.13%Color and Shape:Yellow Solid PowderMolecular weight:212.23-methyl-1,2-dihydroquinolin-2-one
CAS:3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.Formula:C10H9NOPurity:99.62%Color and Shape:SolidMolecular weight:159.18Ref: TM-T50035
1mg35.00€5mg77.00€10mg103.00€25mg170.00€50mg250.00€100mg354.00€200mg480.00€1mL*10mM (DMSO)62.00€dencichine
CAS:Dencichine (ODAP) is a neurotoxic agent and a haemostatic agent, which relates to modulation of the coagulation system, and fibrinolytic system.Formula:C5H8N2O5Purity:99.93% - ≥95%Color and Shape:SolidMolecular weight:176.13Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formula:C26H30N4O5SPurity:97.7% - 99.99%Color and Shape:SolidMolecular weight:510.61Ref: TM-T9497
5mg57.00€10mg82.00€25mg111.00€50mg137.00€100mg205.00€200mg309.00€500mg515.00€1mL*10mM (DMSO)66.00€BMS-P5 free base
CAS:BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.Formula:C27H32N6O2Purity:99.88%Color and Shape:SolidMolecular weight:472.58Ruxolitinib phosphate
CAS:Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formula:C17H21N6O4PPurity:98% - >99.99%Color and Shape:SolidMolecular weight:404.36Ref: TM-T3043
1g583.00€5mg49.00€10mg62.00€25mg78.00€50mg92.00€100mg138.00€200mg215.00€500mg395.00€1mL*10mM (DMSO)56.00€COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formula:C13H8Cl4N2OPurity:98.96%Color and Shape:SolidMolecular weight:350.03ABBV-744
CAS:ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formula:C28H30FN3O4Purity:97.03% - >99.99%Color and Shape:SolidMolecular weight:491.55Ref: TM-T4697
1mg44.00€2mg56.00€5mg90.00€10mg142.00€25mg284.00€50mg409.00€100mg500.00€200mg718.00€1mL*10mM (DMSO)90.00€BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formula:C26H26F3N7O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:525.53Ref: TM-T2488
1mg35.00€2mg43.00€5mg63.00€10mg101.00€25mg212.00€50mg351.00€100mg588.00€1mL*10mM (DMSO)73.00€IOX2
CAS:IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.Formula:C19H16N2O5Purity:98% - 99.59%Color and Shape:SolidMolecular weight:352.34Eicosapentaenoic Acid sodium
CAS:EPA sodium, an oral omega-3, demethylates DNA, reactivates tumor suppressors, and induces vasodilation.Formula:C20H29NaO2Color and Shape:SolidMolecular weight:324.434-Phenylbutyric acid
CAS:4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.Formula:C10H12O2Purity:98.40% - 99.76%Color and Shape:SolidMolecular weight:164.2
