Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2437 products of "Chromatin/Epigenetics"
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KDM4-IN-2
CAS:KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively.Formula:C25H26N6OPurity:98%Color and Shape:SolidMolecular weight:426.51MK-0626
CAS:MK-0626 is an orally available dipeptidyl peptidase IV (DPP-4) inhibitor enhancing AMP, restoring the expression of GLP-1R. promoting neoangiogenesis.Formula:C22H24F2N6O2Purity:99.47% - >99.99%Color and Shape:SolidMolecular weight:442.46Tankyrase-IN-5
CAS:Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitoryFormula:C17H18N2O2Purity:98%Color and Shape:SolidMolecular weight:282.34Brepocitinib
CAS:Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).Formula:C18H21F2N7OPurity:99.82%Color and Shape:SolidMolecular weight:389.4PRMT5-IN-28
CAS:<p>PRMT5-IN-28 (compound 36) serves as an inhibitor of the protein arginine methyltransferase 5 (PRMT5) enzyme, which is implicated in various cellular processes</p>Formula:C18H19ClN4O5Purity:98%Color and Shape:SolidMolecular weight:406.82JAK-IN-5
CAS:JAK-IN-5 is a JAK inhibitor.Formula:C27H31FN6OPurity:98.1% - 99.37%Color and Shape:SolidMolecular weight:474.57PHD-IN-2
CAS:PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 ofFormula:C26H27N7O4Purity:98%Color and Shape:SolidMolecular weight:501.54PRMT5-IN-29
CAS:PRMT5-IN-29 is a potent, orally active inhibitor of PRMT5, exhibiting an IC50 value of 1.5 μM, showing promise for use in advanced cancer research [1].Formula:C18H20Cl3N5O5Purity:98%Color and Shape:SolidMolecular weight:492.74PRMT5-IN-25
CAS:PRMT5-IN-25 (compound 503) is a potent inhibitor of PRMT5, exhibiting an inhibition constant (K i) of 0.06 nM and demonstrating antiproliferative properties [1Formula:C24H21F3N6OPurity:98%Color and Shape:SolidMolecular weight:466.46PARP7-IN-15
CAS:PARP7-IN-15 (Compound 18) is a potent PARP7 inhibitor exhibiting an IC50 of 0.56 nM and demonstrates antitumor activity [1].Formula:C23H24F6N6O4Purity:98%Color and Shape:SolidMolecular weight:562.46KDM5-C70
CAS:KDM5-C70 is an ethyl ester derivative of KDM5-C49.Formula:C17H28N4O3Purity:97.63% - 99.86%Color and Shape:SolidMolecular weight:336.43Sirtuin-1 inhibitor 1
CAS:Sirtuin-1 inhibitor 1 is an inhibitor against deacetylase-1 (Sirtuin-1) and can be used to study senescence and cell death in the organism.Formula:C20H17N3O2Purity:99.1%Color and Shape:SolidMolecular weight:331.37BRD7-IN-1
CAS:BRD7-IN-1, a BI7273 derivative, forms PROTAC VZ185, targeting BRD7/9 with DC50s of 4.5/1.8 nM via VHL ligand linkage.Formula:C22H28Cl2N4O3Purity:98.95%Color and Shape:SolidMolecular weight:467.39Pim-1 kinase inhibitor 5
CAS:<p>Pim-1 kinase inhibitor 5 (Compound 4c), with an IC50 of 0.61 μM, exhibits cytotoxicity against various cancer cell lines, including HepG2, MCF-7, PC3, and HCT-</p>Formula:C22H13Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:406.26Aurora Kinases-IN-4
CAS:Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.Formula:C26H28N8OPurity:98%Color and Shape:SolidMolecular weight:468.55Physachenolide C
CAS:Physachenolide C, a selective BET inhibitor, induces apoptosis and arrests the cell cycle at the G0-G1 phase, exhibiting antitumor activity [1].Formula:C30H40O9Purity:98%Color and Shape:SolidMolecular weight:544.63PHD2-IN-1
CAS:PHD2-IN-1, a potent and orally active HIF prolyl hydroxylase 2 (PHD2) inhibitor, exhibits an IC50 of 22.53 nM and is applicable in anemia research [1].Formula:C21H23ClN4O5Purity:98%Color and Shape:SolidMolecular weight:446.88BET-IN-16
CAS:BET-IN-16 (Comp I), a bromodomain and extra-terminal (BET) inhibitor, demonstrates anticancer activity by impeding the growth of prostate cancer cells.Formula:C31H25N5O3Purity:98%Color and Shape:SolidMolecular weight:515.56Antitumor agent-101
CAS:Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM forFormula:C26H38N6O3Purity:98%Color and Shape:SolidMolecular weight:482.62SJ1461
CAS:SJ1461 is a potent, orally active inhibitor of the BET family, selectively targeting and inhibiting BRD2 (BD1), BRD2 (BD2), BRD4 (BD1), and BRD4 (BD2) withFormula:C21H18ClN7OS2Purity:98%Color and Shape:SolidMolecular weight:484
