Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2437 products of "Chromatin/Epigenetics"
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CBP-IN-1
CAS:CBP-IN-1 (compound 12) acts as a potent CBP inhibitor exhibiting an IC50 of 1.5 nM and additionally suppresses CBP BRET and BRD4(1) with IC50 values of 690 nMFormula:C27H33F2N7OPurity:98%Color and Shape:SolidMolecular weight:509.59Eleven-Nineteen-Leukemia Protein IN-2
CAS:Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].Formula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.45LSD1-UM-109
CAS:LSD1-UM-109 is a highly potent and reversible inhibitor of LSD1, demonstrating an IC50 of 3.1 nM.Formula:C29H27FN6Purity:98%Color and Shape:SolidMolecular weight:478.56Bromodomain inhibitor-12
CAS:Bromodomain Inhibitor-12 (example 303) is a research compound utilized in the study of autoimmune and inflammatory diseases [1].Formula:C28H38N4O5Purity:98%Color and Shape:SolidMolecular weight:510.63MAT2A-IN-10
CAS:MAT2A-IN-10 (Compound 28), an orally active inhibitor of MAT2A, exhibits an IC50 of 26 nM and is utilized in cancer research [1].Formula:C27H24F2N6O4Purity:98%Color and Shape:SolidMolecular weight:534.51PIM1-IN-4
CAS:PIM1-IN-4: strong PIM1 inhibitor, also blocks SGK-1, PKA, CaMK-1, GSK3β, MSK1; promising for cancer studies.Formula:C27H25BrCl2CuN6OPurity:98%Color and Shape:SolidMolecular weight:663.88Eleven-Nineteen-Leukemia Protein IN-3
CAS:ENL YEATS inhibitor Eleven-Nineteen-Leukemia Protein IN-3, IC50 15.4 nM, orally active, suppresses MYC, stabilizes ENL in vitro.Formula:C28H27N5O2Purity:98%Color and Shape:SolidMolecular weight:465.55MAT2A-IN-12
CAS:MAT2A Allosteric Inhibitor 2 is a potent, selective inhibitor exhibiting an IC50 of 5 nM and demonstrates nanomolar efficacy (IC50 = 5 μM) in proliferationFormula:C20H17NO3Purity:98%Color and Shape:SolidMolecular weight:319.35BRD4 Inhibitor-28
CAS:BRD4 Inhibitor-28 (Compound 18), an orally active molecule, selectively inhibits the bromodomains of BRD4 (BRD4-BD1 and BRD4-BD2) with IC50 values of 15 and 55Formula:C23H21N3O3Purity:98%Color and Shape:SolidMolecular weight:387.43Bromodomain inhibitor-12 (edisylate)
CAS:Bromodomain Inhibitor-12 Edisylate (example 303) serves as a bromodomain inhibitor applicable to autoimmune and inflammatory disease research [1].Formula:C30H44N4O11S2Purity:98%Color and Shape:SolidMolecular weight:700.82HIF-2α-IN-9
CAS:HIF-2α-IN-9 (compound 35r) serves as an HIF-2α inhibitor, effectively suppressing VEGF-A with an IC50 of 305 nM, and modulating growth-promoting genes withinFormula:C12H13F5O4S2Purity:98%Color and Shape:SolidMolecular weight:380.35(S,R)-CFT8634
CAS:(S,R)-CFT8634 is a selective and orally active BRD9 protein degrader with potential for researching BRD9-mediated disorders, such as abnormal cellularFormula:C37H45F3N6O5Purity:98%Color and Shape:SolidMolecular weight:710.79CBP/p300-IN-21
CAS:CBP/p300-IN-21 (Compound 5d), a selective inhibitor of CBP/p300 with IC50 values of 0.07 μM for p300 and 1.755 μM for CBP, reduces H3K18Ac levels and inhibitsFormula:C19H16ClNO4Purity:98%Color and Shape:SolidMolecular weight:357.79FM-479
CAS:<p>FM-479, a structural analog of FM-381, lacks inhibition of JAK3/kinases within 100-300 nM, serving as FM-381's negative control.</p>Formula:C25H26N6O2Purity:98%Color and Shape:SolidMolecular weight:442.523WM-586
CAS:WM-586 is a covalent inhibitor of WDR5 that impedes the WDR5-MYC binding.Formula:C20H20F3N5O3SPurity:98%Color and Shape:SolidMolecular weight:467.47JG-2016
CAS:JG-2016, as a histone acetyltransferase 1 inhibitor, inhibits growth of human cancer cell lines and inhibits enzymatic activity in cellulose.Formula:C18H21ClN4O3Purity:99.00% - 99.37%Color and Shape:SolidMolecular weight:376.84GSK217
CAS:GSK217 is a potent and selective inhibitor of the bromo and extraterminal domain (BET) second bromodomain (BD2) with high solubility, utilized in oncology andFormula:C20H20N6OPurity:98%Color and Shape:SolidMolecular weight:360.41AGI-25696
CAS:AGI-25696 inhibits MATA2, blocking MTAP-deleted tumor growth, potential for cancer research.Formula:C27H18N4OPurity:98.40% - 99.74%Color and Shape:SolidMolecular weight:414.46JAK-IN-31
CAS:JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and ≤0.01 µM for Tyk2,Formula:C21H19N7O2S2Purity:98%Color and Shape:SolidMolecular weight:465.55ABBV-712
CAS:<p>ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseases</p>Formula:C24H28N4O5Purity:98%Color and Shape:SolidMolecular weight:452.5
