Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2440 products of "Chromatin/Epigenetics"
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NSC756093
CAS:NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies.Formula:C20H19NO4Purity:99.92%Color and Shape:SolidMolecular weight:337.37Ref: TM-T24557
1mg47.00€5mg92.00€10mg157.00€25mg329.00€50mg490.00€100mg700.00€500mg1,406.00€1mL*10mM (DMSO)117.00€PARP7-IN-16
CAS:PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively.Formula:C25H26FN4NaO4Purity:98%Color and Shape:SolidMolecular weight:488.49GSK217
CAS:GSK217 is a potent and selective inhibitor of the bromo and extraterminal domain (BET) second bromodomain (BD2) with high solubility, utilized in oncology andFormula:C20H20N6OPurity:98%Color and Shape:SolidMolecular weight:360.41MAT2A-IN-10
CAS:MAT2A-IN-10 (Compound 28), an orally active inhibitor of MAT2A, exhibits an IC50 of 26 nM and is utilized in cancer research [1].Formula:C27H24F2N6O4Purity:98%Color and Shape:SolidMolecular weight:534.51KP-544
CAS:KP-544 is an agent of neurotrophin potentiator.Formula:C18H19ClN4OPurity:98%Color and Shape:SolidMolecular weight:342.82PIM-IN-2
CAS:PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) value of 25 nM .Formula:C19H22N4O2Purity:98%Color and Shape:SolidMolecular weight:338.4DNMT-IN-3
CAS:DNMT-IN-3 is a DNA Methyltransferase (DNMT) inhibitor with an IC50 of 60 nM against Plasmodium falciparum (Plasmodium), demonstrating antimalarial activity and suitability for malaria-related research [1].Formula:C37H39N7OColor and Shape:SolidMolecular weight:597.75PARP1-IN-7
CAS:PARP1-IN-7 functions as an anticancer agent by inhibiting poly(ADP-ribose) polymerase-1 (PARP1).Formula:C24H23N5OColor and Shape:SolidMolecular weight:397.47HSP70/SIRT2-IN-2
CAS:<p>HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].</p>Formula:C17H13N3S3Purity:98%Color and Shape:SolidMolecular weight:355.5UNC8153 TFA
CAS:UNC8153 is a NSD2-specific histone-lysine N-methyltransferase degrader, showing selective activity towards NSD2 over NSD1 and NSD3 at 20 µM, and demonstrating aFormula:C35H38F3N5O7Purity:96.44%Color and Shape:SolidMolecular weight:697.7NMS-P953
CAS:NMS-P953: JAK2 inhibitor, reduces tumor growth in SET-2 model, confirmed in vivo action, good pharmacokinetics and safety.Formula:C16H11ClF3N5OColor and Shape:SolidMolecular weight:381.74(S,R)-CFT8634
CAS:(S,R)-CFT8634 is a selective and orally active BRD9 protein degrader with potential for researching BRD9-mediated disorders, such as abnormal cellularFormula:C37H45F3N6O5Purity:98%Color and Shape:SolidMolecular weight:710.79JAK2-IN-4
CAS:JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.Formula:C23H27N5O4SPurity:98%Color and Shape:SolidMolecular weight:469.56KDM5-C70
CAS:KDM5-C70 is an ethyl ester derivative of KDM5-C49.Formula:C17H28N4O3Purity:97.63% - 99.86%Color and Shape:SolidMolecular weight:336.43Ref: TM-T15648
2mg44.00€5mg62.00€10mg88.00€25mg140.00€50mg245.00€100mg490.00€200mg700.00€500mg1,074.00€1mL*10mM (DMSO)73.00€CAY10398
CAS:CAY10398 is a compound that serves as an isoform-selective inhibitor of histone deacetylase (HDAC1).Formula:C15H23N3O3Color and Shape:SolidMolecular weight:293.367TC-A 2317 hydrochloride
CAS:TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.Formula:C19H29ClN6OPurity:98%Color and Shape:SolidMolecular weight:392.93HDAC6/HSP90-IN-1
CAS:HDAC6/HSP90-IN-1 is a potent dual inhibitor of HDAC6 and HSP90 with IC50s 4.3 nM & 46.8 nM, respectively; curbs PD-L1 and tumor growth in H1975 mice.Formula:C28H37N3O6Color and Shape:SolidMolecular weight:511.61PRMT5-IN-28
CAS:<p>PRMT5-IN-28 (compound 36) serves as an inhibitor of the protein arginine methyltransferase 5 (PRMT5) enzyme, which is implicated in various cellular processes</p>Formula:C18H19ClN4O5Purity:98%Color and Shape:SolidMolecular weight:406.82GW814408X
CAS:GW814408X, a kinase chemical genome group (KCGS) compound, inhibits the AURKC kinase, which is involved in cell cycle progression, checkpoint regulation, and cell division. It exhibits cell line-dependent toxicity, such as cytotoxic effects on HeLa cells, and acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially impacting Fluc reporter assays [1].Formula:C19H16N6OMolecular weight:344.37QQN-00358
CAS:QQN-00358 is a novel potent and selective tankyrase (TNKS) inhibitor.Formula:C26H24F3N3O4Color and Shape:SolidMolecular weight:499.48
