Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2547 products of "Chromatin/Epigenetics"
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HDAC6-IN-34
CAS:HDAC6-IN-34 (compound 21), an orally active, selective HDAC6 inhibitor, exhibits an IC50 of 18 nM. It enhances tubulin acetylation levels without impacting histone acetylation in cutaneous T-cell lymphoma cells and suppresses TNF-α secretion in LPS-stimulated macrophage cells. Furthermore, HDAC6-IN-34 demonstrates outstanding anti-arthritic efficacy in rats [1].Formula:C18H18F3N3O3Color and Shape:SolidMolecular weight:381.35DNMT-IN-3
CAS:DNMT-IN-3 is a DNA Methyltransferase (DNMT) inhibitor with an IC50 of 60 nM against Plasmodium falciparum (Plasmodium), demonstrating antimalarial activity and suitability for malaria-related research [1].Formula:C37H39N7OColor and Shape:SolidMolecular weight:597.75OM-1700
CAS:OM-1700 inhibits tankyrase 1 (IC50=127 nM) and 2 (IC50=14 nM); hinders colon cancer cell growth, COLO 320DM (GI50=650 nM).Formula:C25H23FN6O2Color and Shape:SolidMolecular weight:458.49PRMT5-IN-16
CAS:PRMT5-IN-16 (Compound 20) is an antitumor PRMT5 inhibitor linked to epigenetic changes.Formula:C25H34N8O2Color and Shape:SolidMolecular weight:478.59AKB-6899
CAS:AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treatedFormula:C14H11FN2O4Purity:97.87%Color and Shape:SolidMolecular weight:290.25CC-90005
CAS:CC-90005 is a potent, selective oral PKC-θ inhibitor with an IC50 of 8 nM, preferential over PKC-δ, and inhibits T cell activation.Formula:C21H27F2N7O2Color and Shape:SolidMolecular weight:447.48PF-06679142
CAS:PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.Formula:C20H17F2NO3Purity:98%Color and Shape:SolidMolecular weight:357.35Sirt2-IN-5
CAS:Sirt2-IN-5 is a potent inhibitor of SIRT2.Formula:C26H27Cl2N5O3Color and Shape:SolidMolecular weight:528.43EPZ-030456
CAS:EPZ-030456 is an effective and selective inhibitor of the SMYD3.Formula:C28H34ClN5O4SColor and Shape:SolidMolecular weight:572.12Aurora kinase inhibitor-8
CAS:Aurora kinase inhibitor-8 is a highly selective inhibitor of Aurora kinase.Formula:C30H29N7O3Color and Shape:SolidMolecular weight:535.6RK-701
CAS:RK-701: G9a inhibitor, IC50 23-27 nM, increases HbF/γ-Globin/BGLT3, decreases H3K9me2, inhibits BCL11A/ZBTB7A.Formula:C26H30N4O3Color and Shape:SolidMolecular weight:446.54MARK-IN-1
CAS:MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor, (IC50<0.25 nM).Formula:C22H23F2N7OSPurity:98%Color and Shape:SolidMolecular weight:471.53MS023 trihydrochloride
CAS:MS023 trihydrochloride (MS023 3HCl) is a PRMT inhibitor with potential anticancer activity against PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8 for cancer research.Formula:C17H28Cl3N3OPurity:99.81%Color and Shape:SolidMolecular weight:396.78HDAC/HSP90-IN-3
CAS:HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.Formula:C26H33N5O6Color and Shape:SolidMolecular weight:511.57XDM-CBP
CAS:XDM-CBP is an effective and selective CBP/p300 bromodomain inhibitor.Formula:C21H22N2O4Purity:98%Color and Shape:SolidMolecular weight:366.41KDM5-IN-1
CAS:KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM.Formula:C17H20N6OPurity:99.50%Color and Shape:SolidMolecular weight:324.38Ref: TM-T15649
1mg64.00€5mg187.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€500mgTo inquire1mL*10mM (DMSO)137.00€Prolyl Hydroxylase inhibitor 1
CAS:Prolyl Hydroxylase inhibitor 1 is an orally active inhibitor of hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) (IC50 of 62.23 nM).Formula:C19H18ClN5O4Purity:98%Color and Shape:SolidMolecular weight:415.83K-756
CAS:K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 (IC50 = 31 nM) and TNKS2 (IC50 = 36 nM).
Formula:C24H27N5O3Purity:99.81%Color and Shape:SolidMolecular weight:433.5BChE/HDAC6-IN-1
CAS:BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor that exhibits potent and selective inhibition with IC50 values of 4 nM for BChE and 8.9 nM for HDAC6.Formula:C34H43N5O5Purity:98%Color and Shape:SolidMolecular weight:601.74HIF-2α-IN-13
CAS:HIF-2α-IN-13 (18) acts as a HIF-2α inhibitor and exhibits an IC 50 value of 2.7 μM.Formula:C15H14ClF4NO2Color and Shape:SolidMolecular weight:351.72
