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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2602 products of "Chromatin/Epigenetics"

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  • PROTAC BRD4 Degrader-1
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    PROTAC BRD4 Degrader-1

    CAS:
    PROTAC BRD4 Degrader-1 is an efficacious degrader of BRD4(BRD4 BD1,IC50 of 41.8 nM).
    Formula:C40H37N9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:771.78

    Ref: TM-T13833

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    500mg
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  • FTX-6058 hydrochloride
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    FTX-6058 hydrochloride

    CAS:
    FTX-6058 hydrochloride is a potent EED inhibitor, induces HbF, and aids sickle cell and β-thalassemia research.
    Formula:C22H19ClFN5O2
    Color and Shape:Solid
    Molecular weight:439.87

    Ref: TM-T40155

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    HIF-1 inhibitor-5

    HIF-1 inhibitor-5 (Compound 16e) is a potent inhibitor of HIF-1, exhibiting an IC50 value of 2.38 μM and demonstrating significant anti-angiogenic potential [1
    Formula:C28H35NO5
    Color and Shape:Solid
    Molecular weight:465.58

    Ref: TM-T74804

    5mg
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    50mg
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  • PRMT5-IN-13
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    PRMT5-IN-13

    CAS:
    PRMT5-IN-13 is a selective inhibitor of protein arginine methyltransferase 5 (prmt5) .
    Formula:C18H17ClN4O4
    Color and Shape:Solid
    Molecular weight:388.81

    Ref: TM-T39934

    5mg
    873.00€
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    GXH-II-052

    GXH-II-052: Potent BET inhibitor, binds BRD4/BRDT (Kd 0.6-28 nM), anti-proliferative, reduces c-Myc expression.
    Formula:C62H76Cl2F2N14O11S2
    Color and Shape:Solid
    Molecular weight:1366.39

    Ref: TM-T74899

    5mg
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    50mg
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  • C 21
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    C 21

    CAS:
    PRMT1 inhibitor, IC50=1.8μM; 5x more selective than PRMT6; >250x over PRMT3, CARM1.
    Formula:C90H161ClN36O24
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2166.94

    Ref: TM-TP2041

    1mg
    274.00€
  • PROTAC BRD4 Degrader-27
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    PROTAC BRD4 Degrader-27

    CAS:
    PROTAC BRD4 Degrader-27 is a selective PROTAC targeting BRD4, distinguished from BRD2/BRD3. This compound is composed of the E3 ubiquitinase ligand Thalidomide-4-OH, the PROTAC Linker γ-Aminobutyric acid, and the PROTAC target protein ligand PROTAC BRD4 ligand-3. The active control for this target protein ligand is Mivebresib, while the conjugate of the E3 ubiquitin ligase ligand and Linker is identified as Pomalidomide 4'-alkylC3-acid.
    Formula:C37H30F2N6O7
    Color and Shape:Solid
    Molecular weight:708.67

    Ref: TM-T89867

    10mg
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    50mg
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  • OARV-771
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    OARV-771

    CAS:
    OARV-771: VHL-based PROTAC targeting BET; DC50: Brd4-6nM, Brd2-1nM, Brd3-4nM; enhanced cell permeability.
    Formula:C49H59ClN8O8S2
    Color and Shape:Solid
    Molecular weight:987.62

    Ref: TM-T74391

    5mg
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    50mg
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  • Ep300/CREBBP-IN-4
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    Ep300/CREBBP-IN-4

    CAS:
    Ep300/CREBBP-IN-4, an Ep300 & CREBBP inhibitor; IC50: 0.024μM & 0.064μM. For cancer research.
    Formula:C23H22F3N5O3
    Color and Shape:Solid
    Molecular weight:473.45

    Ref: TM-T73923

    5mg
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    50mg
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    HAT-SIL-TG-1&AT

    HAT-SIL-TG-1&AT: a hypoxia-activated JAK inhibitor that curbs HEL cell growth & STAT3/5 phosphorylation in tumors.
    Formula:C60H69N17O11S
    Color and Shape:Solid
    Molecular weight:1236.36

    Ref: TM-T74800

    5mg
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    50mg
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    HDAC6-IN-56

    HDAC6-IN-56 (compound 18d) is an inhibitor of HDAC6, with an IC50 of 1.3 nM. This compound can inhibit the S phase and induce apoptosis in HCT-116 colon cancer cells.

    Formula:C25H27ClN4O4S
    Color and Shape:Solid
    Molecular weight:514.14415

    Ref: TM-T207237

    10mg
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    TO-1187

    TO-1187 is a selective HDAC6 PROTAC degrader with a DC50 of 5.81 nM. It enhances the ubiquitination and subsequent degradation of HDAC6, making it useful for research in hematological malignancies and solid tumors.
    Color and Shape:Odour Solid

    Ref: TM-T206646

    10mg
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  • PROTAC BRD4-DCAF1 degrader-1
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    PROTAC BRD4-DCAF1 degrader-1

    CAS:
    PROTACBRD4-DCAF1 degrader-1 (I-907) is a PROTAC degrader targeting BRD4-DCAF1, exhibiting a DC50 range of 10~100 nM.
    Formula:C60H64Cl2F2N8O9S
    Color and Shape:Solid
    Molecular weight:1182.17

    Ref: TM-T200664

    10mg
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    50mg
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  • PRMT5-IN-11
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    PRMT5-IN-11

    CAS:
    PRMT5-IN-11 demonstrates potent structure-dependent inhibition against the protein methyltransferase PRMT5:MEP50 complex at submicromolar concentrations.
    Formula:C13H17N5O4
    Color and Shape:Solid
    Molecular weight:307.31

    Ref: TM-T40197

    25mg
    1,369.00€
  • Foenumoside B
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    Foenumoside B

    CAS:
    Foenumoside B, a triterpene saponin extracted from Lysimachia foenum-graecum, stimulates AMPK signaling, suppresses PPARγ-induced adipogenesis, and promotes
    Formula:C60H96O25
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1217.39

    Ref: TM-T79949

    5mg
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    50mg
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    BBDDL2204

    BBDDL2204 (compound 13) is a potent and selective covalent inhibitor of EZH2, demonstrating an IC50 of 2.5 nM against EZH2Y641F.
    Formula:C37H47N5O5S
    Color and Shape:Solid
    Molecular weight:673.32979

    Ref: TM-T207472

    10mg
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  • Mersalyl
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    Mersalyl

    CAS:
    Mersalyl is an organic mercurial diuretic.
    Formula:C13H16HgNNaO6
    Color and Shape:Solid
    Molecular weight:505.854

    Ref: TM-T33297

    25mg
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    100mg
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  • JMJD6 inhibitor WL12
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    JMJD6 inhibitor WL12

    CAS:

    WL12 (ZINC6733033): First-in-class JMJD6 inhibitor; halts JMJD6-dependent cervical/liver cancer cell growth.

    Formula:C16H11N3O2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:277.28

    Ref: TM-T9939

    1mg
    39.00€
    5mg
    80.00€
    10mg
    116.00€
    25mg
    190.00€
    50mg
    284.00€
    100mg
    394.00€
    200mg
    560.00€
  • INCB059872
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    INCB059872

    CAS:
    INCB059872: potent, oral, selective LSD1 inhibitor for myeloid leukemia research.
    Formula:C23H34N2O3
    Color and Shape:Solid
    Molecular weight:386.536

    Ref: TM-T39226

    5mg
    873.00€
  • dBRD9
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    dBRD9

    CAS:
    dBRD9 is a PROTAC.
    Formula:C40H45N7O10
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:783.83

    Ref: TM-T31221

    1mg
    129.00€
    5mg
    311.00€
    10mg
    502.00€
    25mg
    874.00€
    50mg
    1,320.00€
    100mg
    1,833.00€
    1mL*10mM (DMSO)
    434.00€