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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2252 products of "Chromatin/Epigenetics"

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  • C646
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    C646

    CAS:
    <p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>
    Formula:C24H19N3O6
    Purity:98% - 99.21%
    Color and Shape:Solid
    Molecular weight:445.42

    Ref: TM-T2452

  • CymitQuimica logo
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    SETDB1-TTD-IN-1 TFA

    <p>SETDB1-TTD-IN-1 TFA: potent, selective SETDB1-TTD inhibitor (Kd: 88 nM), useful for related biological research.</p>
    Formula:C30H32F3N5O4
    Color and Shape:Solid
    Molecular weight:583.6

    Ref: TM-T64120

  • Niraparib tosylate
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    Niraparib tosylate

    CAS:
    <p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>
    Formula:C19H20N4O·C7H8O3S
    Purity:99.34% - 99.87%
    Color and Shape:Solid
    Molecular weight:492.59

    Ref: TM-T6892

  • Acetyl Pentapeptide-1 acetate
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    Acetyl Pentapeptide-1 acetate

    <p>Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.</p>
    Formula:C34H55N9O12
    Purity:99.09%
    Color and Shape:Solid
    Molecular weight:781.86

    Ref: TM-T38318L

  • Splitomicin
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    Splitomicin

    CAS:
    Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a
    Formula:C13H10O2
    Purity:97.09% - 99.11%
    Color and Shape:Solid
    Molecular weight:198.22

    Ref: TM-T6678

  • PFI-1
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    PFI-1

    CAS:
    <p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>
    Formula:C16H17N3O4S
    Purity:98.74% - 99.19%
    Color and Shape:Solid
    Molecular weight:347.39

    Ref: TM-T6222

  • GSK-LSD1 dihydrochloride
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    GSK-LSD1 dihydrochloride

    CAS:
    <p>GSK-LSD1 dihydrochloride: potent LSD1 inhibitor, &gt;1000x selective over MAO-A/B, LSD2, IC50: 16 nM.</p>
    Formula:C14H22Cl2N2
    Purity:98.72% - >99.99%
    Color and Shape:Solid
    Molecular weight:289.24

    Ref: TM-T2315

  • 3-TYP
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    3-TYP

    CAS:
    <p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>
    Formula:C7H6N4
    Purity:99.16% - >99.99%
    Color and Shape:Solid
    Molecular weight:146.15

    Ref: TM-T4108

  • Baricitinib phosphate
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    Baricitinib phosphate

    CAS:
    Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.
    Formula:C16H20N7O6PS
    Purity:99.4% - 99.91%
    Color and Shape:Solid
    Molecular weight:469.41

    Ref: TM-T2360

  • Aurora kinase inhibitor-2
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    Aurora kinase inhibitor-2

    CAS:
    <p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>
    Formula:C23H20N4O3
    Purity:98.66%
    Color and Shape:Solid
    Molecular weight:400.43

    Ref: TM-T9040

  • 2-hexyl-4-Pentynoic Acid
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    2-hexyl-4-Pentynoic Acid

    CAS:
    <p>2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.</p>
    Formula:C11H18O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:182.26

    Ref: TM-T21551

  • Deoxyshikonin
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    Deoxyshikonin

    CAS:
    <p>1.</p>
    Formula:C16H16O4
    Purity:99.36% - ≥95%
    Color and Shape:Solid
    Molecular weight:272.3

    Ref: TM-T5S2347

  • MRTX9768
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    MRTX9768

    CAS:
    <p>MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.</p>
    Formula:C24H17FN6O
    Purity:97.02%
    Color and Shape:Solid
    Molecular weight:424.43

    Ref: TM-T9575

  • RO8191
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    RO8191

    CAS:
    <p>RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.</p>
    Formula:C14H5F6N5O
    Purity:98% - 98.85%
    Color and Shape:Solid
    Molecular weight:373.21

    Ref: TM-T22142

  • PX-478
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    PX-478

    CAS:
    PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.
    Formula:C13H20Cl4N2O3
    Purity:97% - 99.79%
    Color and Shape:Solid
    Molecular weight:394.12

    Ref: TM-T6961

  • AS8351
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    AS8351

    CAS:
    <p>AS8351 inhibits histone demethylase, used with various compounds to turn human lung fibroblasts into cardiomyocytes.</p>
    Formula:C17H13N3O2
    Purity:99.54% - 99.72%
    Color and Shape:Solid
    Molecular weight:291.3

    Ref: TM-T4100

  • MK-4827 Racemate
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    MK-4827 Racemate

    CAS:
    <p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>
    Formula:C19H20N4O
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:320.39

    Ref: TM-T22988

  • 7BIO
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    7BIO

    CAS:
    <p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>
    Formula:C16H10BrN3O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:356.17

    Ref: TM-T22012

  • Selisistat
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    Selisistat

    CAS:
    Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).
    Formula:C13H13ClN2O
    Purity:98.53% - 99.94%
    Color and Shape:Solid
    Molecular weight:248.71

    Ref: TM-T6111

  • SGI-1776
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    SGI-1776

    CAS:
    <p>SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.</p>
    Formula:C20H22F3N5O
    Purity:99.3% - >99.99%
    Color and Shape:Solid
    Molecular weight:405.42

    Ref: TM-T3078