DNA-PK
DNA-PK (DNA-dependent protein kinase) is a key enzyme involved in the repair of DNA double-strand breaks through the non-homologous end joining (NHEJ) pathway. DNA-PK inhibitors block the activity of this kinase, preventing the repair of DNA breaks and leading to increased cell death, particularly in cancer cells. DNA-PK inhibitors are valuable tools in cancer research and therapy, especially in combination with other DNA-damaging treatments. At CymitQuimica, we provide a comprehensive range of high-quality DNA-PK inhibitors to support your research in DNA repair, cancer biology, and therapeutic development.
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Voxtalisib
CAS:934493-76-2
Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 …
Formula:
C13H14N6O
Purity:
98.01% - 99.36%
Color and Shape:
Solid
Molecular weight:
270.29
Ref: TM-T7014
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 560.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Friday 16 May 2025
ETP-45658
CAS:1198357-79-7
ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 …
Formula:
C16H17N5O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
311.34
Ref: TM-T25399
| 1mg | 52.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 175.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 747.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Friday 16 May 2025
CC-115
CAS:1228013-15-7
CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
Formula:
C16H16N8O
Purity:
86.79% - 99.22%
Color and Shape:
Solid
Molecular weight:
336.35
Ref: TM-T3541
| 2mg | 46.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 178.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Friday 16 May 2025
YU238259
CAS:1943733-16-1
YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining …
Formula:
C22H22ClN3O4S
Purity:
99.12% - 99.43%
Color and Shape:
Solid
Molecular weight:
459.95
Ref: TM-T4339
| 1mg | 48.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 543.00 € | ||
| 100mg | 780.00 € | ||
| 500mg | 1,605.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 16 May 2025
LY-294002 hydrochloride
CAS:934389-88-5
LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome …
Formula:
C19H17NO3·HCl
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
343.81
Ref: TM-T4079
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 127.00 € | ||
| 100mg | 447.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 16 May 2025
KU-0060648
CAS:881375-00-4
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 …
Formula:
C33H34N4O4S
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
582.71
Ref: TM-T6557
| 1mg | 59.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 635.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PI-103
CAS:371935-74-9
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for …
Formula:
C19H16N4O3
Purity:
96.59% - 99.3%
Color and Shape:
Solid
Molecular weight:
348.36
Ref: TM-T6143
| 5mg | 57.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 195.00 € | ||
| 100mg | 359.00 € | ||
| 200mg | 547.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Torin 1
CAS:1222998-36-8
Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold …
Formula:
C35H28F3N5O2
Purity:
98.3% - 99.38%
Color and Shape:
Solid
Molecular weight:
607.62
Ref: TM-T6045
| 1mg | 35.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 173.00 € | ||
| 50mg | 311.00 € | ||
| 100mg | 472.00 € | ||
| 500mg | 1,017.00 € |
Estimated delivery in United States, on Friday 16 May 2025
(R)-(-)-Rolipram
CAS:85416-75-7
(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor.
Formula:
C16H21NO3
Purity:
99.6%
Color and Shape:
Solid
Molecular weight:
275.34
Ref: TM-T13448
| 2mg | 47.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 334.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
ZL-2201
CAS:2865115-39-3
ZL-2201 is a potent inhibitor of DNA-PK, demonstrating an IC50 value of 1 nM.
Formula:
C20H25N9O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
503.54
Ref: TM-T78645
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
DNA-PK-IN-10
CAS:2919315-89-0
DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell …
Formula:
C25H28N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
444.53
Ref: TM-T79165
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 11 Jul 2025
DNA-PK-IN-15
CAS:2663852-17-1
DNA-PK-IN-15 (compound 6) acts as an inhibitor of DNA-PK, exhibiting an IC50 value of 0.08 …
Formula:
C23H23N9O
Color and Shape:
Solid
Molecular weight:
441.49
Ref: TM-T201160
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 8 Aug 2025
BAY-8400
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor …
Formula:
C21H17F2N5O
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
393.39
Ref: TM-T9498
| 1mg | 85.00 € | ||
| 5mg | 156.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 464.00 € | ||
| 50mg | 792.00 € | ||
| 100mg | 1,064.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Friday 22 Aug 2025
