DNA-PK
DNA-PK (DNA-dependent protein kinase) is a key enzyme involved in the repair of DNA double-strand breaks through the non-homologous end joining (NHEJ) pathway. DNA-PK inhibitors block the activity of this kinase, preventing the repair of DNA breaks and leading to increased cell death, particularly in cancer cells. DNA-PK inhibitors are valuable tools in cancer research and therapy, especially in combination with other DNA-damaging treatments. At CymitQuimica, we provide a comprehensive range of high-quality DNA-PK inhibitors to support your research in DNA repair, cancer biology, and therapeutic development.
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Torin 1
CAS:1222998-36-8
Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold …
Formula:
C35H28F3N5O2
Purity:
98.3% - 99.38%
Color and Shape:
Solid
Molecular weight:
607.62
Ref: TM-T6045
| 1mg | 36.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 471.00 € | ||
| 500mg | 1,015.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LY-294002 hydrochloride
CAS:934389-88-5
LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome …
Formula:
C19H17NO3·HCl
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
343.81
Ref: TM-T4079
| 1mg | 43.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 440.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Samotolisib
CAS:1386874-06-1
Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.
Formula:
C23H26N4O3
Purity:
98.41% - 99.69%
Color and Shape:
Solid
Molecular weight:
406.48
Ref: TM-T6883
| 5mg | 48.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 368.00 € | ||
| 200mg | 523.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Voxtalisib
CAS:934493-76-2
Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 …
Formula:
C13H14N6O
Purity:
98.01% - 99.36%
Color and Shape:
Solid
Molecular weight:
270.29
Ref: TM-T7014
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 380.00 € | ||
| 100mg | 552.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ETP-45658
CAS:1198357-79-7
ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 …
Formula:
C16H17N5O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
311.34
Ref: TM-T25399
| 1mg | 52.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 505.00 € | ||
| 100mg | 738.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CC-115
CAS:1228013-15-7
CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
Formula:
C16H16N8O
Purity:
86.79% - 99.22%
Color and Shape:
Solid
Molecular weight:
336.35
Ref: TM-T3541
| 2mg | 45.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 175.00 € | ||
| 50mg | 294.00 € | ||
| 100mg | 461.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SF2523
CAS:1174428-47-7
SF2523 is a highly selective and potent inhibitor.
Formula:
C19H17NO5S
Purity:
97.78% - 98.06%
Color and Shape:
Solid
Molecular weight:
371.41
Ref: TM-T3986
| 1mg | 37.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 433.00 € | ||
| 100mg | 639.00 € | ||
| 500mg | 1,336.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
YU238259
CAS:1943733-16-1
YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining …
Formula:
C22H22ClN3O4S
Purity:
99.12% - 99.43%
Color and Shape:
Solid
Molecular weight:
459.95
Ref: TM-T4339
| 1mg | 47.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 771.00 € | ||
| 500mg | 1,576.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
(R)-(-)-Rolipram
CAS:85416-75-7
(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor.
Formula:
C16H21NO3
Purity:
99.6%
Color and Shape:
Solid
Molecular weight:
275.34
Ref: TM-T13448
| 2mg | 46.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 332.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
DNA-PK-IN-10
CAS:2919315-89-0
DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell …
Formula:
C25H28N6O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
444.53
Ref: TM-T79165
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Feb 2025
ZL-2201
CAS:2865115-39-3
ZL-2201 is a potent inhibitor of DNA-PK, demonstrating an IC50 value of 1 nM.
Formula:
C20H25N9O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
503.54
Ref: TM-T78645
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Feb 2025
BAY-8400
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor …
Formula:
C21H17F2N5O
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
393.39
Ref: TM-T9498
| 1mg | 82.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 447.00 € | ||
| 50mg | 762.00 € | ||
| 100mg | 1,025.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Wednesday 19 Mar 2025
Nedisertib
CAS:1637542-33-6
Nedisertib (M3814) (M3814) is a specific inhibitor of DNA-dependent Protein Kinase (DNA-PK, IC50: <3 nM).
Formula:
C24H21ClFN5O3
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
481.91
Ref: TM-TQ0031
| 1mg | Discontinued | Request information | |
| 1ml | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information |
(Rac)-Nedisertib
CAS:1637542-34-7
(Rac)-Nedisertib is a racemate of Nedisertib, a potent inhibitor of DNA-PK(IC50 of <3 nM).
Formula:
C24H21ClFN5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
481.91
Ref: TM-T12672
| 5mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information |
