DNA-PK
DNA-PK (DNA-dependent protein kinase) is a key enzyme involved in the repair of DNA double-strand breaks through the non-homologous end joining (NHEJ) pathway. DNA-PK inhibitors block the activity of this kinase, preventing the repair of DNA breaks and leading to increased cell death, particularly in cancer cells. DNA-PK inhibitors are valuable tools in cancer research and therapy, especially in combination with other DNA-damaging treatments. At CymitQuimica, we provide a comprehensive range of high-quality DNA-PK inhibitors to support your research in DNA repair, cancer biology, and therapeutic development.
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LTURM34
CAS:1879887-96-3
LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM.
Formula:
C24H18N2O3S
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
414.48
Ref: TM-T15789
| 5mg | 44.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 236.00 € | ||
| 100mg | 351.00 € | ||
| 200mg | 513.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
STL127705
CAS:1326852-06-5
STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.
Formula:
C22H20FN5O4
Purity:
97.41% - 99.18%
Color and Shape:
Solid
Molecular weight:
437.42
Ref: TM-T13017
| 1mg | 112.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 700.00 € | ||
| 50mg | 984.00 € | ||
| 100mg | 1,333.00 € | ||
| 500mg | 2,655.00 € | ||
| 1mL*10mM (DMSO) | 315.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
IC 86621
CAS:404009-40-1
IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM …
Formula:
C12H15NO3
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
221.25
Ref: TM-T9760
| 5mg | 37.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 107.00 € | ||
| 100mg | 157.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
NU 7026
CAS:154447-35-5
NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free …
Formula:
C17H15NO3
Purity:
100% - 100%
Color and Shape:
Solid
Molecular weight:
281.31
Ref: TM-T2433
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 444.00 € | ||
| 200mg | 624.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD 6482
CAS:1173900-33-8
AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 …
Formula:
C22H24N4O4
Purity:
99.79% - 99.95%
Color and Shape:
Solid
Molecular weight:
408.45
Ref: TM-T6087
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 509.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Compound 401
CAS:168425-64-7
Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets …
Formula:
C16H15N3O2
Purity:
99.19% - 99.76%
Color and Shape:
Solid
Molecular weight:
281.31
Ref: TM-T3586
| 2mg | 34.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 112.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 307.00 € | ||
| 200mg | 439.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LY294002
CAS:154447-36-6
LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 …
Formula:
C19H17NO3
Purity:
98% - 99.96%
Color and Shape:
Pale Yellow Solid
Molecular weight:
307.34
Ref: TM-T2008
| 5mg | 39.00 € | ||
| 10mg | 50.00 € | ||
| 50mg | 71.00 € | ||
| 100mg | 93.00 € | ||
| 200mg | 121.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PIK-75 hydrochloride
CAS:372196-77-5
PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits …
Formula:
C16H14BrN5O4S·HCl
Purity:
97.82%
Color and Shape:
Solid
Molecular weight:
488.74
Ref: TM-T2287
| 5mg | 42.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 121.00 € | ||
| 100mg | 171.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PI-3065
CAS:955977-50-1
PI-3065 is a novel potent and selective PI3K p110δ inhibitor.
Formula:
C27H31FN6OS
Purity:
98.39% - ≥95%
Color and Shape:
Solid
Molecular weight:
506.64
Ref: TM-T2083
| 1mg | 38.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 200.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 540.00 € | ||
| 500mg | 1,107.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD-7648
CAS:2230820-11-6
AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM …
Formula:
C18H20N8O2
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
380.4
Ref: TM-T7122
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DMNB
CAS:20357-25-9
DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor, an enzyme involved in the NHEJ pathway …
Formula:
C9H9NO5
Purity:
≥98%
Color and Shape:
Yellow Solid
Molecular weight:
211.17
Ref: TM-T8637
| 200mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KU-57788
CAS:503468-95-9
NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).
Formula:
C25H19NO3S
Purity:
100% - 99.87%
Color and Shape:
Solid
Molecular weight:
413.49
Ref: TM-T6276
| 2mg | 40.00 € | ||
| 5mg | 58.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 386.00 € | ||
| 500mg | 909.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Torin 2
CAS:1223001-51-1
Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for …
Formula:
C24H15F3N4O
Purity:
98.31% - 99.32%
Color and Shape:
Solid
Molecular weight:
432.4
Ref: TM-T6100
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 252.00 € | ||
| 100mg | 375.00 € | ||
| 200mg | 557.00 € | ||
| 500mg | 885.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Leniolisib
CAS:1354690-24-6
Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).
Formula:
C21H25F3N6O2
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
450.46
Ref: TM-T5166
| 1mg | 78.00 € | ||
| 5mg | 151.00 € | ||
| 10mg | 219.00 € | ||
| 25mg | 411.00 € | ||
| 50mg | 639.00 € | ||
| 100mg | 924.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
OSI-027
CAS:936890-98-1
OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 …
Formula:
C21H22N6O3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
406.44
Ref: TM-T6319
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PIK-90
CAS:677338-12-4
PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) …
Formula:
C18H17N5O3
Purity:
98.25% - ≥95%
Color and Shape:
Solid
Molecular weight:
351.36
Ref: TM-T2461
| 5mg | 46.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 142.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PIK-75
CAS:372196-67-3
PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Formula:
C16H14BrN5O4S
Purity:
100% - 99.88%
Color and Shape:
Solid
Molecular weight:
452.28
Ref: TM-T2667
| 5mg | 45.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 180.00 € | ||
| 100mg | 276.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PI3K-IN-1
CAS:1349796-36-6
PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits …
Formula:
C31H29N5O6S
Purity:
97.03% - 98%
Color and Shape:
Solid
Molecular weight:
599.66
Ref: TM-T1826
| 1mg | 35.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 496.00 € | ||
| 500mg | 1,096.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KU-0060648
CAS:881375-00-4
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 …
Formula:
C33H34N4O4S
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
582.71
Ref: TM-T6557
| 1mg | 58.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 441.00 € | ||
| 100mg | 631.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PI-103
CAS:371935-74-9
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for …
Formula:
C19H16N4O3
Purity:
96.59% - 99.3%
Color and Shape:
Solid
Molecular weight:
348.36
Ref: TM-T6143
| 5mg | 58.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 125.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 363.00 € | ||
| 200mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
