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DNA Methyltransferase

DNA Methyltransferase

DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.

Found 422 products of "DNA Methyltransferase"

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  • 5'-Azido-5'-deoxyadenosine
    Targetmol
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    5'-Azido-5'-deoxyadenosine

    CAS:
    <p>5'-Azido-5'-deoxyadenosine is a purine nucleoside analogue, inhibit Trichomonas vaginalis and PRMT5 , click chemistry alkyne, DBCO, or BCN groups.</p>
    Formula:C10H12N8O3
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:292.25

    Ref: TM-TNU1255

  • PROTAC EZH2 Degrader-1
    Targetmol
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    PROTAC EZH2 Degrader-1

    CAS:
    <p>PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.</p>
    Formula:C54H67N7O8
    Color and Shape:Solid
    Molecular weight:942.15

    Ref: TM-T74602

  • MS8511 hydrochloride
    Targetmol
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    MS8511 hydrochloride

    CAS:
    <p>MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics.</p>
    Formula:C28H42ClN5O3
    Color and Shape:Solid
    Molecular weight:532.12

    Ref: TM-T204198

  • (R)-HH2853
    Targetmol
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    (R)-HH2853

    CAS:
    <p>(R)-HH2853, a mutant EZH2 inhibitor, IC50 &lt;100 nM for EZH2-Y641F, targets cancer/autoimmune diseases.</p>
    Formula:C31H36F3N7O3
    Purity:97.53% - 98.85%
    Color and Shape:Solid
    Molecular weight:611.66

    Ref: TM-T73116

  • 2'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
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    2'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride

    CAS:
    <p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>
    Formula:C9H13ClFN3O4
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:281.67

    Ref: TM-TNU0425

  • O6BTG-octylglucoside
    Targetmol
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    O6BTG-octylglucoside

    CAS:
    O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).
    Formula:C24H34BrN5O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:616.53

    Ref: TM-T11419

  • EZM0414 TFA
    Targetmol
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    EZM0414 TFA

    CAS:
    <p>EZM0414 TFA (SETD2-IN-1 TFA) is a SETD2 inhibitor with anticancer and antiproliferative effects for the study of leukemia and immune dysfunction.</p>
    Formula:C24H30F4N4O4
    Purity:98.88%
    Color and Shape:Solid
    Molecular weight:514.51

    Ref: TM-T36975

  • DA-3003-1
    Targetmol
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    DA-3003-1

    CAS:
    <p>DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.</p>
    Formula:C15H16ClN3O3
    Purity:99.27% - 99.79%
    Color and Shape:Solid
    Molecular weight:321.76

    Ref: TM-T16357

  • EHMT2-IN-1
    Targetmol
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    EHMT2-IN-1

    CAS:
    <p>EHMT2-IN-1: potent EHMT inhibitor, for blood disorders/cancer research; IC50s &lt;100 nM for EHMT1/2 peptides and cellular EHMT2.</p>
    Formula:C18H23N7O
    Color and Shape:Solid
    Molecular weight:353.42

    Ref: TM-T11166

  • (R)-GSK-3685032
    Targetmol
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    (R)-GSK-3685032

    CAS:
    <p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>
    Formula:C22H24N6OS
    Color and Shape:Solid
    Molecular weight:420.54

    Ref: TM-T39648

  • EPZ020411
    Targetmol
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    EPZ020411

    CAS:
    <p>EPZ020411 is a specific and effective inhibitor of PRMT6 (IC50=10 nM).</p>
    Formula:C25H38N4O3
    Color and Shape:Solid
    Molecular weight:442.6

    Ref: TM-T4314

  • PR5-LL-CM01
    Targetmol
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    PR5-LL-CM01

    CAS:
    <p>PR5-LL-CM01 is a novel protein arginine methyltransferase 5 (PRMT5) inhibitor in colorectal and pancreatic cancers.</p>
    Formula:C23H27N7
    Color and Shape:Solid
    Molecular weight:401.51

    Ref: TM-T28448

  • AZ505 ditrifluoroacetate
    Targetmol
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    AZ505 ditrifluoroacetate

    CAS:
    <p>AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).</p>
    Formula:C33H40Cl2F6N4O8
    Color and Shape:Solid
    Molecular weight:805.59

    Ref: TM-T10427

  • 5-Aza-2'-deoxycytidine
    TCI
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    5-Aza-2'-deoxycytidine

    CAS:
    Formula:C8H12N4O4
    Purity:>98.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:228.21

    Ref: 3B-A2232

    20mg
    71.00€
    100mg
    213.00€
  • AS-85
    Targetmol
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    AS-85

    CAS:
    <p>AS-85 is an ASH1L inhibitor with anti-leukemic activity that inhibits leukemic cell growth and increases cLogP.</p>
    Formula:C26H28F3N5O3S2
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:579.66

    Ref: TM-T39861

  • UNC0379
    Targetmol
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    UNC0379

    CAS:
    <p>UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.</p>
    Formula:C23H35N5O2
    Purity:94.41% - 99.97%
    Color and Shape:Solid
    Molecular weight:413.56

    Ref: TM-T1841

  • EPZ005687
    Targetmol
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    EPZ005687

    CAS:
    <p>EPZ005687 is a potent and selective inhibitor of EZH2.</p>
    Formula:C32H37N5O3
    Purity:97.06% - 99.64%
    Color and Shape:Solid
    Molecular weight:539.67

    Ref: TM-T1905

  • Piribedil
    Targetmol
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    Piribedil

    CAS:
    <p>Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.</p>
    Formula:C16H18N4O2
    Purity:99.79% - 99.82%
    Color and Shape:Solid
    Molecular weight:298.34

    Ref: TM-T3278

  • MRTX-1719
    Targetmol
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    MRTX-1719

    CAS:
    <p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of &lt;10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>
    Formula:C23H18ClFN6O2
    Purity:98.27% - 99.18%
    Color and Shape:Solid
    Molecular weight:464.88

    Ref: TM-T40254

  • C-7280948
    Targetmol
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    C-7280948

    CAS:
    <p>C-7280948 is a PRMT1 inhibitor.</p>
    Formula:C14H16N2O2S
    Purity:99.55% - ≥95%
    Color and Shape:Solid
    Molecular weight:276.35

    Ref: TM-T2097