DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
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N-Phthalyl-L-tryptophan
CAS:48208-26-0
Formula:
C19H14N2O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
334.3255
Ref: IN-DA003U4E
| 10mg | 52.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 78.00 € | ||
| 250mg | 108.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Decitabine
CAS:2353-33-5
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.
Formula:
C8H12N4O4
Purity:
99% - 99.87%
Color and Shape:
Physical Description Fine White Crystalline Powder Used As A Drug
Molecular weight:
228.21
Ref: TM-T1508
| 1g | 183.00 € | ||
| 50mg | 36.00 € | ||
| 100mg | 46.00 € | ||
| 200mg | 64.00 € | ||
| 500mg | 118.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MAK683
CAS:1951408-58-4
MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in …
Formula:
C20H17FN6O
Purity:
97.98% - 99.92%
Color and Shape:
Solid
Molecular weight:
376.39
Ref: TM-T15201
| 1mg | 52.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 404.00 € | ||
| 50mg | 593.00 € | ||
| 100mg | 828.00 € | ||
| 500mg | 1,719.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
![Cyclohexanecarboxylic acid,3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-,(1S…](https://static.cymitquimica.com/products/IN/thumb/DA00I681.jpg)
Cyclohexanecarboxylic acid,3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-,(1S,3R,4R,5R)-
CAS:327-97-9
Formula:
C16H18O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
354.3087
Ref: IN-DA00I681
| 1g | 24.00 € | ||
| 5g | 58.00 € | ||
| 10g | 85.00 € | ||
| 25g | 153.00 € | ||
| 100g | 523.00 € | ||
| 250mg | 25.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Amodiaquine dihydrochloride dihydrate
CAS:6398-98-7
Amodiaquine dihydrochloride dihydrate (Amodiaquin hydrochloride) is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory …
Formula:
C20H28Cl3N3O3
Purity:
99.9%
Color and Shape:
Solid
Molecular weight:
464.82
Ref: TM-T0381
| 50mg | 42.00 € | ||
| 100mg | 54.00 € | ||
| 200mg | 81.00 € | ||
| 500mg | 115.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)
CAS:304-20-1
Formula:
C8H9ClN4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
196.6369
Ref: IN-DA003006
| 1g | 34.00 € | ||
| 5g | 63.00 € | ||
| 25g | 193.00 € | ||
| 100g | 482.00 € | ||
| 100mg | 25.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
CAS:446-72-0
Formula:
C15H10O5
Purity:
97%
Color and Shape:
Solid
Molecular weight:
270.2369
Ref: IN-DA00I8G3
| 1g | 25.00 € | ||
| 5g | 24.00 € | ||
| 10g | 37.00 € | ||
| 25g | 64.00 € | ||
| 50g | 92.00 € | ||
| 100g | 139.00 € | ||
| 100mg | 25.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
3,4-Dihydroxycinnamic Acid
CAS:331-39-5
Formula:
C9H8O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
180.1574
Ref: IN-DA0033IN
| 5g | 21.00 € | ||
| 10g | 25.00 € | ||
| 1kg | 228.00 € | ||
| 25g | 27.00 € | ||
| 100g | 61.00 € | ||
| 500g | 170.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
DC-05
CAS:890643-16-0
DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM …
Formula:
C25H25N3O
Purity:
98.95%
Color and Shape:
Solid
Molecular weight:
383.49
Ref: TM-T15080
| 1mg | 128.00 € | ||
| 2mg | 184.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 412.00 € | ||
| 25mg | 680.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,291.00 € | ||
| 500mg | 2,589.00 € | ||
| 1mL*10mM (DMSO) | 311.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Ref: IN-DA003824
| 1g | 34.00 € | ||
| 5g | 66.00 € | ||
| 25g | 168.00 € | ||
| 100g | 628.00 € | ||
| 2.5g | 49.00 € | ||
| 100mg | To inquire | ||
| 250mg | 25.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MS1943
CAS:2225938-17-8
MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).
Formula:
C42H54N8O3
Purity:
95.41% - 95.82%
Color and Shape:
Solid
Molecular weight:
718.93
Ref: TM-T13780
| 1mg | 60.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 364.00 € | ||
| 50mg | 616.00 € | ||
| 100mg | 1,027.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
SETD7-IN-1
SETD7-IN-1 (compound 7), a PFI-2 analogue, acts as both a substrate and inhibitor of histone …
Purity:
98%
Ref: TM-T81175
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Ziftomenib
CAS:2134675-36-6
Ziftomenib (KO-539) is an inhibitor of menin-MLL interaction with antitumor activity and can be used …
Formula:
C33H42F3N9O2S2
Purity:
99.65%
Color and Shape:
Liquid
Molecular weight:
717.871
Ref: TM-T39585
| 1mg | 112.00 € | ||
| 5mg | 268.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 603.00 € | ||
| 50mg | 925.00 € | ||
| 100mg | 1,368.00 € | ||
| 200mg | 1,846.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PRMT5-IN-31
PRMT5-IN-31 (Compound 3m), a selective PRMT5 inhibitor (IC50: 0.31 μM), increases hnRNP E1 protein levels …
Formula:
C21H24N2O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
336.43
Ref: TM-T79274
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
OTS186935 FA
OTS186935 FA is a protein methyltransferase SUV39H2 inhibitor.OTS186935 FA inhibits tumor growth in MDA-MB-231 breast …
Formula:
C26H28ClN5O4
Purity:
98.16%
Color and Shape:
Soild
Molecular weight:
509.98
Ref: TM-T12344L1
| 1mg | 94.00 € | ||
| 5mg | 229.00 € | ||
| 10mg | 382.00 € | ||
| 25mg | 692.00 € | ||
| 50mg | 1,072.00 € | ||
| 100mg | 1,497.00 € | ||
| 500mg | 2,985.00 € | ||
| 1mL*10mM (DMSO) | 265.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ZZM-1220
ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM …
Formula:
C25H29N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
447.53
Ref: TM-T79776
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
PRMT4-IN-3
PRMT4-IN-3 (compound 56) serves as a potent class I protein arginine methyltransferase (PRMT) inhibitor, specifically …
Formula:
C23H29N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
419.52
Ref: TM-T79355
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
UNC7096
UNC7096 is a potent, selective degrader of NSD2-PWWP1, exhibiting a dissociation constant (Kd) of 46 …
Formula:
C61H87N7O18S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1238.44
Ref: TM-T79616
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
NSD2-IN-4
NSD2-IN-4 is a potent, selective inhibitor of the NSD2-SET domain, showing promise for the treatment …
Formula:
C18H14ClN3O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
355.78
Ref: TM-T79617
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
MS9715
MS9715 is a potent and selective NSD3-targeting PROTAC, designed by leveraging BI-9321, which targets the …
Formula:
C58H74FN9O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1028.33
Ref: TM-T79615
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
