DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
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SW2_110A
CAS:2579696-95-8
SW2_110A: Cell-permeable, CBX8 ChD inhibitor, Kd 800 nM; 5x selective over other CBXs in vitro.
Formula:
C42H60N6O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
760.96
Ref: TM-T36798
| 1mg | 106.00 € | ||
| 5mg | 270.00 € | ||
| 25mg | 744.00 € | ||
| 50mg | 1,057.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
PRMT3-IN-4
PRMT3-IN-4 (intermediate 15) is an inhibitor of Protein arginine methyltransferase 3 (PRMT3) and serves as …
Ref: TM-T200459
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
DNMT1/HDAC-IN-1
DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory …
Ref: TM-T200728
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Dihydro-5-azacytidine
CAS:62488-57-7
Dihydro-5-azacytidine (DHAC) is a nucleoside analog that interrupts DNA methylation by integrating into DNA. It …
Formula:
C8H14N4O5
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
246.22
Ref: TM-T40713
| 25mg | 1,422.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
EPZ020411 2HCl (1700663-41-7(free base))
EPZ020411 is an effective and specific small molecule PRMT6 inhibitor (IC50=10 nM).
Formula:
C25H40Cl2N4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
515.51
Ref: TM-T4334
| 2mg | 106.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 289.00 € | ||
| 25mg | 603.00 € | ||
| 1mL*10mM (DMSO) | 289.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Ref: TM-T200731
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Ref: TM-T200597
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
TB22
TB22 is a non-nucleoside inhibitor of DOT1LR231Q with anticancer activity. It inhibits the malignant phenotype …
Ref: TM-T200492
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Ziftomenib
CAS:2134675-36-6
Ziftomenib (KO-539) is an inhibitor of menin-MLL interaction with antitumor activity and can be used …
Formula:
C33H42F3N9O2S2
Purity:
99.65%
Color and Shape:
Liquid
Molecular weight:
717.871
Ref: TM-T39585
| 1mg | 112.00 € | ||
| 5mg | 268.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 603.00 € | ||
| 50mg | 925.00 € | ||
| 100mg | 1,368.00 € | ||
| 200mg | 1,846.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
iso-Azalansta
CAS:143393-29-7
(2R,4S)-Azalanstat (Iso-Azalansta) is a selective heme oxygenase (HO) inhibitor that is used in the study …
Formula:
C22H24ClN3O2S
Purity:
100% - 99.40%
Color and Shape:
Soild
Molecular weight:
429.96
Ref: TM-T25127L
| 1mg | 187.00 € | ||
| 5mg | 462.00 € | ||
| 10mg | 661.00 € | ||
| 25mg | 1,031.00 € | ||
| 50mg | 1,423.00 € | ||
| 100mg | 1,881.00 € | ||
| 200mg | 2,568.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
BAY-6035
CAS:2247890-13-5
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more …
Formula:
C22H28N4O3
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
396.48
Ref: TM-T36631
| 5mg | 36.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 166.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Tazemetostat trihydrochloride
CAS:1403255-00-4
Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in …
Formula:
C34H47Cl3N4O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
682.12
Ref: TM-T15240
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
UNC6852
CAS:2688842-08-0
UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and …
Formula:
C43H48N10O6S
Purity:
≥98%
Color and Shape:
Liquid
Molecular weight:
832.97
Ref: TM-T13954
| 1mg | 130.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 446.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,003.00 € | ||
| 100mg | 1,380.00 € | ||
| 1mL*10mM (DMSO) | 375.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
SW2_110A acetate
SW2_110A acetate is a selective, cell-permeable chromobox inhibitor of homologue CBX8 (Kd = 800 nM) …
Formula:
C44H64N6O9
Purity:
98%
Color and Shape:
Soild
Molecular weight:
821.01
Ref: TM-T36798L
| 1mg | 153.00 € | ||
| 5mg | 300.00 € | ||
| 10mg | 497.00 € | ||
| 25mg | 937.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Chaetocin
CAS:28097-03-2
Chaetocin: a natural histone methyltransferase inhibitor; IC50 of 0.8, 2.5, and 3 μM for dSU(VAR)3-9, …
Formula:
C30H28N6O6S4
Purity:
98.15% - 98.82%
Color and Shape:
Solid
Molecular weight:
696.84
Ref: TM-T6803
| 1mg | 132.00 € | ||
| 5mg | 391.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
UNC 0631
CAS:1320288-19-4
UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).
Formula:
C37H61N7O2
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
635.93
Ref: TM-T2354
| 1mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 459.00 € | ||
| 100mg | 668.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Tulmimetostat
CAS:2567686-02-4
Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in …
Formula:
C28H36ClN3O5S
Purity:
98.04%
Color and Shape:
Liquid
Molecular weight:
562.12
Ref: TM-T40199
| 1mg | 36.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 532.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
EZH2-IN-15
CAS:2098545-98-1
A compound inhibits EZH2, overexpressed in cancers, affecting Treg activity and innate immunity.
Formula:
C32H44N4O4
Purity:
98.85%
Color and Shape:
Liquid
Molecular weight:
548.72
Ref: TM-T67883
| 1mg | 154.00 € | ||
| 5mg | 339.00 € | ||
| 10mg | 515.00 € | ||
| 25mg | 816.00 € | ||
| 50mg | 1,103.00 € | ||
| 100mg | 1,476.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
DC-S239
CAS:303141-21-1
Ethyl 2-amino-4-methyl-5-thiophene carboxylate is a SETD7 inhibitor (IC50=4.59μM) with anticancer properties.
Formula:
C15H15N3O5S
Purity:
99.36%
Color and Shape:
Liquid
Molecular weight:
349.36
Ref: TM-T60002
| 1mg | 52.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 344.00 € | ||
| 50mg | 557.00 € | ||
| 100mg | 884.00 € | ||
| 200mg | 1,209.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
MS8511 HCl
MS8511 HCl is a G9a/GLP inhibitor with anticancer activity that can be used in the …
Formula:
C28H42ClN5O3
Purity:
97.83% - 98.90%
Color and Shape:
Liquid
Molecular weight:
532.12
Ref: TM-T63351L
| 1mg | 182.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 645.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,871.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
