DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
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BRD9539
CAS:1374601-41-8
BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with …
Formula:
C24H21N3O3
Purity:
98% - 99.44%
Color and Shape:
Solid
Molecular weight:
399.44
Ref: TM-T7378
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 274.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
LLY-507
CAS:1793053-37-8
LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.
Formula:
C36H42N6O
Purity:
99.56% - 99.93%
Color and Shape:
Solid
Molecular weight:
574.76
Ref: TM-T6879
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 552.00 € | ||
| 100mg | 787.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
OICR-9429
CAS:1801787-56-3
OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.
Formula:
C29H32F3N5O3
Purity:
99.13% - 99.93%
Color and Shape:
Solid
Molecular weight:
555.59
Ref: TM-T6916
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 311.00 € | ||
| 100mg | 502.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Tazemetostat
CAS:1403254-99-8
Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.
Formula:
C34H44N4O4
Purity:
98.24% - ≥95%
Color and Shape:
Solid
Molecular weight:
572.74
Ref: TM-T1788
| 5mg | 65.00 € | ||
| 10mg | 88.00 € | ||
| 50mg | 111.00 € | ||
| 100mg | 167.00 € | ||
| 200mg | 253.00 € | ||
| 500mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
MRTX9768
CAS:2629314-68-5
MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target …
Formula:
C24H17FN6O
Purity:
98.48%
Color and Shape:
Liquid
Molecular weight:
424.43
Ref: TM-T9575
| 1mg | 321.00 € | ||
| 5mg | 677.00 € | ||
| 10mg | 1,074.00 € | ||
| 25mg | 1,605.00 € | ||
| 50mg | 2,157.00 € | ||
| 100mg | 2,822.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Pinometostat
CAS:1380288-87-8
Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective …
Formula:
C30H42N8O3
Purity:
97.56% - 99.83%
Color and Shape:
Solid
Molecular weight:
562.71
Ref: TM-T3099
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 88.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
TP-064
CAS:2080306-20-1
TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation …
Formula:
C28H34N4O2
Purity:
97.85%
Color and Shape:
Solid
Molecular weight:
458.6
Ref: TM-T28996
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 710.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
AMI-1
CAS:20324-87-2
AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast …
Formula:
C21H14N2Na2O9S2
Purity:
97.53% - 99.9%
Color and Shape:
Drypowder
Molecular weight:
548.45
Ref: TM-T2352
| 5mg | 50.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 180.00 € | ||
| 100mg | 283.00 € | ||
| 500mg | 682.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GSK591
CAS:1616391-87-7
GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine …
Formula:
C22H28N4O2
Purity:
99.35% - 99.77%
Color and Shape:
Solid
Molecular weight:
380.48
Ref: TM-T6853
| 1mg | 48.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 710.00 € | ||
| 500mg | 1,483.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
3-deazaneplanocin A HCl
CAS:120964-45-6
3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog …
Formula:
C12H15ClN4O3
Purity:
93.24% - 98.34%
Color and Shape:
Solid
Molecular weight:
298.73
Ref: TM-T6360
| 1mg | 95.00 € | ||
| 5mg | 310.00 € | ||
| 10mg | 432.00 € | ||
| 25mg | 772.00 € | ||
| 50mg | 1,130.00 € | ||
| 100mg | 1,549.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
MS023
CAS:1831110-54-3
MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 …
Formula:
C17H25N3O
Purity:
98.31% - 99.28%
Color and Shape:
Solid
Molecular weight:
287.4
Ref: TM-T6900
| 1mg | 39.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 243.00 € | ||
| 50mg | 378.00 € | ||
| 100mg | 560.00 € | ||
| 500mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
MR837
CAS:1210906-48-1
MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.
Formula:
C16H14N2OS
Purity:
99.29% - 99.77%
Color and Shape:
Solid
Molecular weight:
282.36
Ref: TM-T8879
| 2mg | 40.00 € | ||
| 5mg | 58.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 375.00 € | ||
| 200mg | 530.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
SGC2085
CAS:1821908-48-8
SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).
Formula:
C19H24N2O2
Purity:
99.71% - 99.86%
Color and Shape:
Solid
Molecular weight:
312.41
Ref: TM-T7089
| 1mg | 88.00 € | ||
| 2mg | 119.00 € | ||
| 5mg | 227.00 € | ||
| 10mg | 341.00 € | ||
| 25mg | 563.00 € | ||
| 50mg | 820.00 € | ||
| 100mg | 1,130.00 € | ||
| 1mL*10mM (DMSO) | 160.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
BRD4770
CAS:1374601-40-7
BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.
Formula:
C25H23N3O3
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
413.47
Ref: TM-T1923
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GSK503
CAS:1346572-63-1
GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.
Formula:
C31H38N6O2
Purity:
98% - 99.74%
Color and Shape:
Solid
Molecular weight:
526.67
Ref: TM-T1775
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 560.00 € | ||
| 500mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
6-Thioguanine
CAS:154-42-7
6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used …
Formula:
C5H5N5S
Purity:
100% - 98.75%
Color and Shape:
Odorless Or Almost Odorless Pale Yellow Crystalline Powder
Molecular weight:
167.19
Ref: TM-T3089
| 50mg | 48.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 79.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
5-Methyl-2'-deoxycytidine
CAS:838-07-3
5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in …
Formula:
C10H15N3O4
Purity:
99.18% - 99.69%
Color and Shape:
Solid
Molecular weight:
241.24
Ref: TM-T7457
| 1g | 55.00 € | ||
| 500mg | 42.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
5-Fluoro-2'-deoxycytidine
CAS:10356-76-0
5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .
Formula:
C9H12FN3O4
Purity:
97.91%
Color and Shape:
Fine White Powder
Molecular weight:
245.21
Ref: TM-T7718
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 67.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 145.00 € | ||
| 100mg | 210.00 € | ||
| 200mg | 313.00 € | ||
| 500mg | 525.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
UNC3866 TFA(1872382-47-2 free base)
CAS:1872382-48-3
UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.
Formula:
C45H67F3N6O10
Purity:
98.6%
Color and Shape:
Solid
Molecular weight:
909.04
Ref: TM-T4021L
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 229.00 € | ||
| 50mg | 339.00 € | ||
| 100mg | 472.00 € | ||
| 200mg | 655.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GSK343
CAS:1346704-33-3
GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against …
Formula:
C31H39N7O2
Purity:
98% - 99.9%
Color and Shape:
Solid
Molecular weight:
541.69
Ref: TM-T6059
| 5mg | 59.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 283.00 € | ||
| 100mg | 512.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
