DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
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BIX-01294
CAS:935693-62-2
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
Formula:
C28H38N6O2
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
490.64
Ref: TM-T7697
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € | ||
| 200mg | 723.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UNC1215
CAS:1415800-43-9
UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 …
Formula:
C32H43N5O2
Purity:
98% - 99.04%
Color and Shape:
Solid
Molecular weight:
529.72
Ref: TM-T2379
| 2mg | 41.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 333.00 € | ||
| 100mg | 494.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
EPZ004777
CAS:1338466-77-5
EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
Formula:
C28H41N7O4
Purity:
98.99% - 99.32%
Color and Shape:
Solid
Molecular weight:
539.67
Ref: TM-T3081
| 1mg | 39.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 519.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UNC1999
CAS:1431612-23-5
UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 …
Formula:
C33H43N7O2
Purity:
100% - 99.7%
Color and Shape:
Solid
Molecular weight:
569.74
Ref: TM-T3057
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 281.00 € | ||
| 100mg | 505.00 € | ||
| 500mg | 1,105.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Amodiaquine
CAS:86-42-0
Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
Formula:
C20H22ClN3O
Purity:
99.78%
Color and Shape:
Crystals From Absolute Ethanol Solid
Molecular weight:
355.86
Ref: TM-T8381
| 1mg | 52.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 442.00 € | ||
| 100mg | 634.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MS049
CAS:1502816-23-0
MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with …
Formula:
C15H24N2O
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
248.36
Ref: TM-T4378
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 353.00 € | ||
| 200mg | 520.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SGC707
CAS:1687736-54-4
SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.
Formula:
C16H18N4O2
Purity:
98.45% - 99.75%
Color and Shape:
Solid
Molecular weight:
298.34
Ref: TM-T3084
| 10mg | 64.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 321.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SETDB1-TTD-IN-1
CAS:2755823-12-0
SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor …
Formula:
C28H31N5O2
Purity:
98.26% - 99.38%
Color and Shape:
Solid
Molecular weight:
469.58
Ref: TM-T9742
| 1mg | 251.00 € | ||
| 5mg | 618.00 € | ||
| 10mg | 880.00 € | ||
| 25mg | 1,319.00 € | ||
| 50mg | 1,762.00 € | ||
| 100mg | 2,385.00 € | ||
| 1mL*10mM (DMSO) | 739.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
HLCL-61 hydrochloride
CAS:1158279-20-9
HLCL-61 hydrochloride (HLCL-61 HCL) is a potent and selective PRMT5 inhibitor for the treatment of …
Formula:
C23H24N2O·ClH
Purity:
99.88% - 99.91%
Color and Shape:
Solid
Molecular weight:
380.91
Ref: TM-T6857
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 112.00 € | ||
| 100mg | 205.00 € | ||
| 200mg | 287.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BRD9539
CAS:1374601-41-8
BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with …
Formula:
C24H21N3O3
Purity:
98% - 99.44%
Color and Shape:
Solid
Molecular weight:
399.44
Ref: TM-T7378
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 274.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LLY-507
CAS:1793053-37-8
LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.
Formula:
C36H42N6O
Purity:
99.56% - 99.93%
Color and Shape:
Solid
Molecular weight:
574.76
Ref: TM-T6879
| 1mg | 44.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 540.00 € | ||
| 100mg | 770.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
OICR-9429
CAS:1801787-56-3
OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.
Formula:
C29H32F3N5O3
Purity:
99.13% - 99.93%
Color and Shape:
Solid
Molecular weight:
555.59
Ref: TM-T6916
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 307.00 € | ||
| 100mg | 491.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GSK3326595
CAS:1616392-22-3
GSK3326595 (EPZ015938) is an inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50:6.2 nM.).
Formula:
C24H32N6O3
Purity:
97.43% - 97.7%
Color and Shape:
Solid
Molecular weight:
452.55
Ref: TM-T5745
| 5mg | 46.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 183.00 € | ||
| 100mg | 345.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tazemetostat
CAS:1403254-99-8
Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.
Formula:
C34H44N4O4
Purity:
98.24% - ≥95%
Color and Shape:
Solid
Molecular weight:
572.74
Ref: TM-T1788
| 5mg | 64.00 € | ||
| 10mg | 88.00 € | ||
| 50mg | 110.00 € | ||
| 100mg | 171.00 € | ||
| 200mg | 247.00 € | ||
| 500mg | 465.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MRTX9768
CAS:2629314-68-5
MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target …
Formula:
C24H17FN6O
Purity:
98.48%
Color and Shape:
Liquid
Molecular weight:
424.43
Ref: TM-T9575
| 1mg | 317.00 € | ||
| 5mg | 669.00 € | ||
| 10mg | 1,060.00 € | ||
| 25mg | 1,585.00 € | ||
| 50mg | 2,129.00 € | ||
| 100mg | 2,785.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Pinometostat
CAS:1380288-87-8
Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective …
Formula:
C30H42N8O3
Purity:
97.56% - 99.83%
Color and Shape:
Solid
Molecular weight:
562.71
Ref: TM-T3099
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 87.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TP-064
CAS:2080306-20-1
TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation …
Formula:
C28H34N4O2
Purity:
97.85%
Color and Shape:
Solid
Molecular weight:
458.6
Ref: TM-T28996
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 480.00 € | ||
| 100mg | 695.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMI-1
CAS:20324-87-2
AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast …
Formula:
C21H14N2Na2O9S2
Purity:
97.53% - 99.9%
Color and Shape:
Drypowder
Molecular weight:
548.45
Ref: TM-T2352
| 5mg | 51.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 177.00 € | ||
| 100mg | 277.00 € | ||
| 500mg | 669.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GSK591
CAS:1616391-87-7
GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine …
Formula:
C22H28N4O2
Purity:
99.35% - 99.77%
Color and Shape:
Solid
Molecular weight:
380.48
Ref: TM-T6853
| 1mg | 48.00 € | ||
| 2mg | 61.00 € | ||
| 5mg | 98.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 480.00 € | ||
| 100mg | 698.00 € | ||
| 500mg | 1,455.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
3-deazaneplanocin A HCl
CAS:120964-45-6
3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog …
Formula:
C12H15ClN4O3
Purity:
93.24% - 98.34%
Color and Shape:
Solid
Molecular weight:
298.73
Ref: TM-T6360
| 1mg | 94.00 € | ||
| 5mg | 304.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 755.00 € | ||
| 50mg | 1,106.00 € | ||
| 100mg | 1,520.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
