Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(229 products)
- Annexin A(16 products)
- Aromatase(23 products)
- Estrogen/progestogen Receptor(66 products)
- GPR(1 products)
- Glucocorticoid Receptor(164 products)
- LHRH(2 products)
- Opioid Receptor(327 products)
- Prostaglandin Receptor(122 products)
- RAAS(89 products)
- Reductase(51 products)
- Somatostatin(57 products)
- Thyroid hormone receptor(THR)(34 products)
- Vasopressin Receptor(48 products)
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Found 3419 products of "Endocrinology/Hormones"
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Hydrocortisone-d4
CAS:Hydrocortisone-d4 is a deuterated compound of Hydrocortisone. Hydrocortisone has a CAS number of 50-23-7. Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects.Formula:C21H26D4O5Color and Shape:SolidMolecular weight:366.48Estrone-d2
CAS:Estrone-d2 is a deuterated compound of Estrone. Estrone has a CAS number of 53-16-7. Estrone is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.Formula:C18H20D2O2Color and Shape:SolidMolecular weight:272.38Lisinopril
CAS:Lisinopril, an ACE inhibitor, treats hypertension, heart failure, heart attacks, and prevents diabetes-related eye and kidney issues.Formula:C21H31N3O5Purity:97.59% - 99.34%Color and Shape:SolidMolecular weight:405.49L-6424
CAS:L-6424 is an intermediate of Amiodarone and a non-selective ion channel blocker. It has an antiarrhythmic.Formula:C19H17IO3Purity:98%Color and Shape:SolidMolecular weight:420.24AR antagonist 6
CAS:AR antagonist 6 (compound 6i), a diphenyl ether androgen receptor (AR) antagonist, binds to the AR with an affinity of 120 nM. It demonstrates low toxicity and effective in vitro activity in the golden Syrian hamster ear model. [19] [1]Formula:C16H12F3NO2Color and Shape:SolidMolecular weight:307.27ASN04885796
CAS:ASN04885796 is a neuroprotective, specific GPR17 agonist with an EC50=2.27 nM for GPR17-mediated GTPγS binding and study neurodegenerative diseasesFormula:C28H28FN5O4Purity:95.36%Color and Shape:SolidMolecular weight:517.55Ref: TM-T30163
1mg72.00€5mg156.00€1mL*10mM (DMSO)173.00€10mg246.00€25mg407.00€50mg595.00€100mg849.00€200mg1,144.00€CGP-53153
CAS:CGP-53153 is a steroidal inhibitor of 5 alpha-reductase (IC50s: 36 and 262 nM in rat and human prostatic tissue).Formula:C23H33N3O2Purity:98%Color and Shape:SolidMolecular weight:383.53Estromustine
CAS:Estromustine, an active metabolite of estramustine phosphate, is used to treat prostate cancer.Formula:C23H29Cl2NO3Color and Shape:SolidMolecular weight:438.39GDC-2992
CAS:GDC-2992 is a selective androgen receptor (AR) degradator that degrades AR and inhibits proliferation in VCaP cells,CRPC.Formula:C45H51ClN8O5Purity:99.82%Color and Shape:SoildMolecular weight:819.39A 274
CAS:A 274 is a highly aromatic, monosubstituted phenol antioxidant generated during differentiation of neuroblastoma cells.Formula:C19H14O2Purity:98%Color and Shape:SolidMolecular weight:274.31T3-ATA (S-isomer)
T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone.Formula:C19H16I3NO6SPurity:98%Color and Shape:SolidMolecular weight:767.11Fenclofenac
CAS:Fenclofenac: a non-steroidal anti-inflammatory that blocks T4 and T3 binding to TBG.Formula:C14H10Cl2O3Color and Shape:SolidMolecular weight:297.13GRT2932Q
CAS:GRT2932Q is a nonpeptidic agonist of the opioid receptor-like 1 (ORL1) [1].Formula:C25H26ClN3OColor and Shape:SolidMolecular weight:419.95Exendin 4
Originally identified in Gila monster lizard (Heloderma suspectum), exendin-4 is an incretin mimetic, an analog of glucagon-like-peptide-1 (GLP-1), it stimulates insulin secretion and modulates gastric emptying to slow the entry of ingested sugars into the bloodstream. Exendin-4 is resistant to cleavage by plasma DPP-IV unlike GLP-1. This gives it a longer half-life and duration of action than GLP-1, as well as greater potency in vivo. Exendin-4 increases insulin sensitivity and improves glucose tolerance and is currently used for the treatment of Type 2 diabetes mellitus in its synthetic form Exenatide. Exendin-4 also promotes the production and proliferation of beta-cells leading to regeneration of the pancreas. It is a ligand to the exendin receptor and increases pancreatic acinni cAMP levels. However, the GLP-1 analog was found to have a toxic effect by inducing hypotension due to relaxation of the cardiac smooth muscle.
Molecular weight:4,186.63 g/molLosartan D4
CAS:Losartan D4 (DuP-753 D4) is a deuterated isotope of Losartan for isotopic tracing. Losartan is an angiotensin II receptor antagonist (IC50=20 nM).Formula:C22H23ClN6OPurity:98%Color and Shape:SolidMolecular weight:426.94Irbesartan-d4
CAS:Irbesartan-d4 (Irbesartan D4), a deuterated compound of Irbesartan, is an angiotensin receptor blocker and is used in the study of cardiovascular disease.Formula:C25H28N6OPurity:>99.99%Color and Shape:SolidMolecular weight:432.55Triamcinolone acetonide-d6
CAS:Triamcinolone acetonide-d6 is a deuterated compound of Triamcinolone acetonide. Triamcinolone acetonide has a CAS number of 76-25-5. Triamcinolone acetonide is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.Formula:C24H25D6FO6Color and Shape:SolidMolecular weight:440.533,3',5-Triiodothyronine-(tyrosine ring-13C6)
CAS:3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.
Formula:C4C11H12I3NO4Color and Shape:SolidMolecular weight:656.93L-Thyroxine-13C6
CAS:L-Thyroxine-13C6 is the 13C labeled compound of L-Thyroxine. L-Thyroxine has a CAS number of 51-48-9. Levothyroxine is the major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.Formula:C4C11H11I4NO4Molecular weight:782.83α-Cortolone
CAS:α-Cortolone, a metabolite of the glucocorticoid cortisol (hydrocortisone), is produced through the action of 20α-hydroxysteroid dehydrogenase (20α-HSD) via a tetrahydrocortisone (THE) intermediate. Studies indicate that urinary levels of α-cortolone are reduced in patients experiencing severe anorexia nervosa and postmenopausal women diagnosed with endometrial adenocarcinoma, in comparison to postmenopausal women without the condition.Formula:C21H34O5Color and Shape:SolidMolecular weight:366.49
