Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(229 products)
- Annexin A(16 products)
- Aromatase(22 products)
- Estrogen/progestogen Receptor(64 products)
- GPR(1 products)
- Glucocorticoid Receptor(165 products)
- LHRH(2 products)
- Opioid Receptor(325 products)
- Prostaglandin Receptor(122 products)
- RAAS(86 products)
- Reductase(51 products)
- Somatostatin(57 products)
- Thyroid hormone receptor(THR)(32 products)
- Vasopressin Receptor(48 products)
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Found 3369 products of "Endocrinology/Hormones"
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LY2066948
CAS:LY2066948 is a selective oral estrogen receptor modulator (SERM) with high affinity for estrogen receptors ERα and ERβ (Ki of 0.51 and 1.36 nM, respectively) and displays potent anti-estrogenic activity. It effectively blocks the increase in uterine weight induced by ethinylestradiol in immature rats. LY2066948 is utilized in the research of uterine fibroids and myomas.Formula:C30H31NO5SColor and Shape:SolidMolecular weight:517.64EN171
CAS:EN171, a covalent ligand, selectively binds to C38 and C96 on 14-3-3, intensifying 14-3-3's interactions with ERα, YAP, and TAZ. This action impairs both estrogen receptor and Hippo pathway transcriptional activities. Beyond serving as a molecular glue to augment native protein interactions, EN171 also functions as a covalent recruiter for 14-3-3 in heterobifunctional molecules. This facilitates the sequestration of nuclear neo-substrates, such as BRD4 and BLC6, into the cytosol.Formula:C17H22N2OColor and Shape:SolidMolecular weight:270.37Sunobinop
CAS:Sunobinop (S 117957) is an opioid receptor-like orphan receptor (ORL1) modulator.Formula:C26H33N3O3Color and Shape:SolidMolecular weight:435.56CCG258747
CAS:CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.Formula:C28H27FN4O4Color and Shape:SolidMolecular weight:502.54MK-6913
CAS:MK-6913 is a potent and selective agonist of estrogen receptor β.Formula:C25H27N3O2Purity:98%Color and Shape:SolidMolecular weight:401.5Elacestrant S enantiomer dihydrochloride
Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.Formula:C30H40Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:531.56MB-07344 sodium
"MB-07344 sodium is a TR-β agonist with a 2.17 nM Ki, boosts Atorvastatin's cholesterol-lowering effects in various animals."Formula:C19H25NaO5PPurity:98%Color and Shape:SolidMolecular weight:387.36Norbinaltorphimine dihydrochloride
CAS:Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.Formula:C40H45Cl2N3O6Purity:98.17% - 99.88%Color and Shape:SolidMolecular weight:734.71Ref: TM-T12241
1mg38.00€5mg85.00€10mg120.00€25mg235.00€50mg409.00€100mg652.00€200mg908.00€1mL*10mM (DMSO)124.00€AVE 0991
CAS:AVE 0991 is a nonpeptide analog of angiotensin-(1-7), a Mas agonist with inhibitory effects on [125I]-Ang-(1-7) and on neuroinflammation in Alzheimer's disease.Formula:C29H32N4O5S2Purity:99.73%Color and Shape:SolidMolecular weight:580.72Urotensin-II receptor antagonist-1
CAS:Urotensin-II receptor antagonist-1 (compound 1) is a human Urotensin II receptor antagonist with low oral bioavailability (F=0-3% in rats) and a Ki of 16 nM in HEK293 cells expressing human recombinant UT receptors. It inhibits cytochrome P450 enzymes (IC50=0.75 μM for CYP2D6; 1.4 μM for CYP3A4), suppresses κ opioid receptors (EC50=3.2 μM), and targets cardiac sodium channels (Ki=2.5 μM).Formula:C25H31Cl2N3OColor and Shape:SolidMolecular weight:460.439DS69910557
DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.Formula:C32H33Cl2FN4O3Color and Shape:SolidMolecular weight:611.53AT1R antagonist 2
AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).Formula:C29H37N5O4S2Color and Shape:SolidMolecular weight:583.77A 74273
CAS:A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.Formula:C44H74N4O8Purity:98%Color and Shape:SolidMolecular weight:787.08Naltrindole 5′-isothiocyanate
CAS:Naltrindole 5′-isothiocyanate (5'-NTII) is an irreversible delta opioid receptor antagonist that counters the analgesic effects induced by DSLET without altering the effects caused by DPDPE.Formula:C27H25N3O3SColor and Shape:SolidMolecular weight:471.571rel-SB-612111 hydrochloride
CAS:NOP receptor antagonistFormula:C24H30Cl3NOPurity:98%Color and Shape:SolidMolecular weight:454.86Estrogen receptor antagonist 6
CAS:Estrogen receptor antagonist 6 is a potent blocker of estrogen signaling, regulating various biological effects. (Compound 166)Formula:C25H31F3N2O3Color and Shape:SolidMolecular weight:464.52AP5
CAS:AP5: GPR40 agonist, positive allosteric modulator; rat hIP1 EC50: 0.49 nM.Formula:C28H28FNO4Purity:98%Color and Shape:SolidMolecular weight:461.52JDTic Dihydrochloride
CAS:JDTic Dihydrochloride is a high-affinity and selective κ-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling,antidepressant.Formula:C28H41Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:538.55TRβ agonist 1
CAS:TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM.Formula:C29H25FN2O8Color and Shape:SolidMolecular weight:548.52ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research.Formula:C17H21N5OColor and Shape:SolidMolecular weight:311.38
