Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(229 products)
- Annexin A(16 products)
- Aromatase(23 products)
- Estrogen/progestogen Receptor(66 products)
- GPR(1 products)
- Glucocorticoid Receptor(165 products)
- LHRH(2 products)
- Opioid Receptor(327 products)
- Prostaglandin Receptor(122 products)
- RAAS(89 products)
- Reductase(51 products)
- Somatostatin(57 products)
- Thyroid hormone receptor(THR)(33 products)
- Vasopressin Receptor(48 products)
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Found 3420 products of "Endocrinology/Hormones"
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PROTAC ERα Degrader-7
CAS:PROTAC ERα Degrader-7 (Compound i-320) is a powerful PROTAC degrader targeting the estrogen receptor alpha (ERα), exhibiting a DC50 of 0.000006 µM. This compound consists of a cereblon-binding segment, LBM, connected to ERBM, an ERα-binding ligand that includes a benzofused partially saturated 6-membered carbocyclic or heterocyclic ring [1].Formula:C46H49F2N5O4Color and Shape:SolidMolecular weight:773.91Melanin Concentrating Hormone, salmon TFA
MCH (salmon) TFA is a 19-amino-acid neuropeptide affecting appetite, energy, sleep, and heart health via GPCR SLC-1/GPR24 and MCHR2.Formula:C91H140F3N27O26S4Color and Shape:SolidMolecular weight:2213.5Aclerastide
CAS:Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.Formula:C42H64N12O11Color and Shape:SolidMolecular weight:913.03PROTAC ERα Degrader-8
CAS:PROTAC ERα Degrader-8 (compound ii-56), a highly potent degrader of Erα, achieves a DC50 of just 0.000006 μM in MCF7 cells [1].Formula:C47H51N5O4Color and Shape:SolidMolecular weight:749.94[Nphe1]Nociceptin(1-13)NH2 TFA
[Nphe1]Nociceptin(1-13)NH2 is a selective nociceptin receptor antagonist with potential analgesic properties, pKi=8.4, pA2=6.0.Formula:C63H101F3N22O17Color and Shape:SolidMolecular weight:1495.61Floramanoside C
CAS:Floramanoside C exhibits 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities [1].Formula:C21H18O15Color and Shape:SolidMolecular weight:510.36[Ala17]-MCH TFA
'[Ala17]-MCH TFA is an MCH analogue, a selective MCHR1 ligand (Ki=0.16 nM) with high affinity (Kd=0.37 nM), and low MCHR2 affinity (Ki=34 nM).Formula:C99H156F3N29O28S4Color and Shape:SolidMolecular weight:2385.73MCH(human, mouse, rat) TFA
MCH TFA, a peptide, selectively binds MCH1R and MCH2R with IC50 of 0.3nM, 1.5nM; EC50s are 3.9nM (MCH1R) and 0.1nM (MCH2R) in CHO cells.Formula:C107H161F3N30O28S4Color and Shape:SolidMolecular weight:2500.86Abaloparatide
CAS:Abaloparatide (BA 058) is a selective PTHR1 analog that promotes bone growth and may be researched for osteoporosis.Formula:C174H300N56O49Color and Shape:SolidMolecular weight:3960.59hFSH-β-(33-53) (TFA)
hFSH-β-(33-53) TFA, a thiol-containing peptide representing the second follicle-stimulating hormone receptor (FSHR) binding domain, acts as an FSHR antagonist.Formula:C115H183N31O32SxC2HF3O2Color and Shape:SolidMolecular weight:2657.96Yp537
CAS:Yp537 acts as an estrogen receptor (ER) inhibitor, specifically preventing the dimerization of the human estrogen receptor [1].Formula:C64H104N13O22PSColor and Shape:SolidMolecular weight:1470.62(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin
CAS:'(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin blocks oxytocin receptors, stopping oxytocin effects on CA1 neuron currents.'Formula:C45H69N9O12S2Color and Shape:SolidMolecular weight:992.21Eprosartan
CAS:Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.Formula:C23H24N2O4SPurity:99.99%Color and Shape:SolidMolecular weight:424.51TrxR1 prodrug-1
TrxR1 prodrug-1 (compound 5u) is a potent inhibitor of TrxR1, demonstrating significant antitumor activity in nude mice and NSCLC organoids.Formula:C22H30N2O6S2Color and Shape:SolidMolecular weight:482.6139,10-Dihydrophenanthrene
CAS:9,10-Dihydrophenanthrene has inhibitory activity against the androgen receptor and can be used in related research in the field of life sciences.Formula:C14H12Purity:98.76%Color and Shape:SolidMolecular weight:180.25DDHF20
DDHF20 is an inhibitor of Staphylococcus aureus, specifically targeting and inhibiting its thioredoxin reductase (TrxR) by acting as a competitive inhibitor at the NADPH binding site. DDHF20 shows potential for research in combating infections related to Staphylococcus aureus.Formula:C34H28O4Color and Shape:SolidMolecular weight:500.58Rimexolone
CAS:Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye.Formula:C24H34O3Color and Shape:SolidMolecular weight:370.52Tetrahydro Aldosterone
CAS:Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.Formula:C21H32O5Color and Shape:SolidMolecular weight:364.48PRL 2915
CAS:PRL 2915 is a potent antagonist of the human somatostatin subtype 2 receptor (hsst 2), exhibiting a binding affinity (K_i) of 12 nM [1].Formula:C59H71ClN12O8S2Color and Shape:SolidMolecular weight:1175.85PRO20
PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.
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