Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(229 products)
- Annexin A(16 products)
- Aromatase(23 products)
- Estrogen/progestogen Receptor(66 products)
- GPR(1 products)
- Glucocorticoid Receptor(165 products)
- LHRH(2 products)
- Opioid Receptor(327 products)
- Prostaglandin Receptor(122 products)
- RAAS(89 products)
- Reductase(51 products)
- Somatostatin(57 products)
- Thyroid hormone receptor(THR)(33 products)
- Vasopressin Receptor(48 products)
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Found 3420 products of "Endocrinology/Hormones"
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Nurr1 agonist 8
CAS:Nurr1 agonist 8 is a low-affinity Nurr1 agonist that can be used to study neurological diseases such as Parkinson's.Formula:C14H10Cl2O3Purity:99.79%Color and Shape:SolidMolecular weight:297.13UFP-512
CAS:UFP-512 is a selective delta-opioid (DOP) receptor agonist.Formula:C31H33N5O5Purity:98%Color and Shape:SolidMolecular weight:555.62YXG-158
CAS:YXG-158 (Compound 23-h), an orally active androgen receptor (AR) degrader and cytochrome P450 17A1 (CYP17A1) inhibitor, exhibits AR degradation with a DC50 of 1Formula:C30H36FN3OPurity:98%Color and Shape:SolidMolecular weight:473.62Triiodothyronine Sulfate
CAS:Triiodothyronine sulfate: Hypothyroidism prodrug, metabolizes into active thyroid hormone T3, binds and activates TRβ1.Formula:C15H11I3NNaO7SPurity:98%Color and Shape:SolidMolecular weight:753.02GPR40 Agonist 2
CAS:GPR40 Agonist 2 is a GPR40 agonist. It can be used in the research of diabetes.Formula:C24H30O3Purity:98%Color and Shape:SolidMolecular weight:366.49ES 8891
CAS:ES 8891 is an inhibitor of renin.Formula:C42H60N6O6SPurity:98%Color and Shape:SolidMolecular weight:777.03RTI-13951-33
CAS:RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional assay).Formula:C28H33N3O3Purity:98%Color and Shape:SolidMolecular weight:459.58Estrogen receptor antagonist 5
CAS:Compound 165: Potent estrogen receptor antagonist; useful for metastatic disease research.Formula:C25H31F3N2O3Color and Shape:SolidMolecular weight:464.52Androgen receptor antagonist 5
CAS:AR antagonist 5 blocks AR (IC50: 6.17 μM), hinders LNCaP cell growth, and has anti-tumor effects in mouse models.Formula:C21H15F4N5O3SColor and Shape:SolidMolecular weight:493.43MB-07344
CAS:MB-07344 is a selective THR-β (thyroid hormone receptor β) agonist with a Ki of 2.17 nM, capable of reducing plasma total cholesterol (TPC).Formula:C19H25O5PPurity:99.32%Color and Shape:SolidMolecular weight:364.37Icalcaprant
CAS:Icalcaprant is a kappa-opioid receptor antagonist [1].Formula:C23H26N4O3Purity:98%Color and Shape:SolidMolecular weight:406.48DPI-3290
CAS:DPI-3290 is a specific agonist of opioid receptors (Ki: 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively) with potentFormula:C30H34FN3O2Purity:98%Color and Shape:SolidMolecular weight:487.61SQ 32970
CAS:SQ 32970 is a potent Endothia aspartic proteinase inhibitor.Formula:C33H51N5O4SColor and Shape:SolidMolecular weight:613.85DS08210767
CAS:DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.Formula:C31H39N5O2Purity:98.79%Color and Shape:SolidMolecular weight:513.67Giredestrant tartrate
CAS:Giredestrant tartrate: a new oral, selective non-steroidal ER antagonist, inhibits ER-mediated gene activation and degrades ER protein, treating tumors.Formula:C31H37F5N4O7Purity:97.01%Color and Shape:SolidMolecular weight:672.64GW-803430
CAS:GW-803430: potent MCH R1 antagonist, pIC50=9.3, orally effective against obesity in animals.Formula:C25H24ClN3O3SPurity:98.07% - 98.97%Color and Shape:SolidMolecular weight:481.99MB-07811
CAS:MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity.Formula:C28H32ClO5PPurity:99.74% - 99.94%Color and Shape:SolidMolecular weight:514.98Ranirestat
CAS:Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathyFormula:C17H11BrFN3O4Purity:96.10% - 99.44%Color and Shape:SolidMolecular weight:420.19Rovatirelin
CAS:Rovatirelin (S-0373) is a TRH analog that improves motor dysfunction in a rat model of cytosine arabinoside-induced spinal cerebellar degeneration.Formula:C16H22N4O4SPurity:99.59%Color and Shape:SolidMolecular weight:366.43Baxdrostat
CAS:Baxdrostat is an aldosterone synthase inhibitor.Formula:C22H25N3O2Purity:99.8%Color and Shape:SolidMolecular weight:363.45Ref: TM-T61373
1mg71.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg236.00€25mg393.00€50mg550.00€100mg707.00€200mg982.00€CO23
CAS:CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.Formula:C19H18I2N2O4Purity:98.08%Color and Shape:SolidMolecular weight:592.17AMG 837 calcium hydrate
CAS:AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM.Formula:C52H44CaF6O8Purity:98.07%Color and Shape:SolidMolecular weight:950.97LX1
CAS:LX1, an anti-prostate cancer compound, specifically targets the androgen receptor (AR), AR variants, and the steroidogenic enzyme AKR1C3. It inhibits AKR1C3's enzymatic function, decreases the conversion of androstenedione to testosterone, and reduces the expression of both AR and AR-V7, subsequently downregulating their target genes. Additionally, LX1 is effective in overcoming tumor cell resistance to Enzalutamide, and when combined with Enzalutamide, it further suppresses tumor growth.Formula:C22H15F6NO2Color and Shape:SolidMolecular weight:439.35AR ligand-44
CAS:AR ligand-44 is an androgen receptor (androgen receptor) ligand that can be utilized in the synthesis of PROTACs such as [ARD-2051].Formula:C23H24ClN3O2Color and Shape:SolidMolecular weight:409.91FSH receptor antagonist 1
CAS:FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s) protein-coupled human follicle-stimulating hormone (FSH) receptor. It exhibits an IC50 value of 28 nM in cell lines expressing the human FSH receptor. This compound significantly inhibits follicle growth and ovulation in in vitro mouse models.Formula:C33H32N2O2Color and Shape:SolidMolecular weight:488.619AKR1C3-IN-7
AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.Formula:C24H20N2O4Color and Shape:SolidMolecular weight:400.43C108297
CAS:C108297: glucocorticoid modulator, combats diet obesity/inflammation, reduces appetite/lipid storage, boosts fat burn.Formula:C30H36FN3O4SPurity:98%Color and Shape:SolidMolecular weight:553.69ERRα antagonist-2
CAS:ERRα antagonist-2 is an estrogen-related receptor α inverse agonist, inhibiting migration and invasion in ER-negative MDA-MB-231,breast cancer.Formula:C19H16N2O6SPurity:99.26%Color and Shape:SolidMolecular weight:400.41LNS8801
CAS:LNS8801 is an orally active agonist of the G protein-coupled estrogen receptor (GPER). By activating GPER, LNS8801 mediates downstream signaling pathways, such as promoting cAMP production and activating CREB signaling, which results in antitumor activities like inhibiting tumor cell proliferation, inducing cell differentiation, and enhancing tumor immunogenicity. It is applicable in research across various cancers, such as melanoma, pancreatic cancer, colorectal cancer, and lung cancer, as well as studies exploring the role of GPER in normal physiological and pathological processes.Formula:C21H18BrNO3Color and Shape:SolidMolecular weight:412.277Dazucorilant
CAS:Dazucorilant (CORT113176), a selective non-steroidal GR modulator, has high affinity with a K i <1 nM, useful for neurological research.Formula:C29H22F4N4O3SColor and Shape:SolidMolecular weight:582.57A4B17
A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment.Formula:C14H7F4NSColor and Shape:SolidMolecular weight:297.27ER degrader 10
CAS:ER degrader 10 (Compound 51) is an orally active estrogen receptor (ER) selective degrader and antagonist, with a DC50 of 0.43 nM and an IC50 of 0.56 nM. It inhibits the proliferation of ER-positive cells, with an IC50 ranging from 0 to 15 nM. ER degrader 10 exhibits weak inhibitory activity on the hERG channel, with an IC50 greater than 40 μM. It has blood-brain barrier permeability, with a brain/plasma ratio (Kp) of 3.05. In mouse models, ER degrader 10 demonstrates antitumor activity.Formula:C28H29F2NO3SColor and Shape:SolidMolecular weight:497.597GPR81 agonist 2
CAS:GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 µM for hGPR81 and 0.123 µM for hGPR109A, respectively.Formula:C26H27ClN6O5S2Color and Shape:SolidMolecular weight:603.11MB-07344 sodium
"MB-07344 sodium is a TR-β agonist with a 2.17 nM Ki, boosts Atorvastatin's cholesterol-lowering effects in various animals."Formula:C19H25NaO5PPurity:98%Color and Shape:SolidMolecular weight:387.36EN171
CAS:EN171, a covalent ligand, selectively binds to C38 and C96 on 14-3-3, intensifying 14-3-3's interactions with ERα, YAP, and TAZ. This action impairs both estrogen receptor and Hippo pathway transcriptional activities. Beyond serving as a molecular glue to augment native protein interactions, EN171 also functions as a covalent recruiter for 14-3-3 in heterobifunctional molecules. This facilitates the sequestration of nuclear neo-substrates, such as BRD4 and BLC6, into the cytosol.Formula:C17H22N2OColor and Shape:SolidMolecular weight:270.37KF-19418
CAS:KF-19418 is a follicle stimulant that directly activates follicles in vitro and promotes hair growth in vivo.Formula:C21H14N4OColor and Shape:SolidMolecular weight:338.36Allyphenyline oxalate
CAS:The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.Formula:C16H20N2O5Color and Shape:SolidMolecular weight:320.34BU09059
CAS:BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).Formula:C28H37N3O5Purity:98%Color and Shape:SolidMolecular weight:495.61ACT 178882
CAS:ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).Formula:C33H38Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:647.03GLPG0492 (R enantiomer)
CAS:GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, a novel selective androgen receptor modulator.Formula:C19H14F3N3O3Color and Shape:SolidMolecular weight:389.33AVE 0991
CAS:AVE 0991 is a nonpeptide analog of angiotensin-(1-7), a Mas agonist with inhibitory effects on [125I]-Ang-(1-7) and on neuroinflammation in Alzheimer's disease.Formula:C29H32N4O5S2Purity:99.73%Color and Shape:SolidMolecular weight:580.72AP5 sodium
CAS:AP5 sodium: potent oral GPR40 agonist, enhances ligands, may aid type II diabetes research.Formula:C28H27FNNaO4Color and Shape:SolidMolecular weight:483.515JDTic Dihydrochloride
CAS:JDTic Dihydrochloride is a high-affinity and selective κ-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling,antidepressant.Formula:C28H41Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:538.55ADX61623
CAS:ADX61623 is an effective negative allosteric modulator (NAM) of the follicle-stimulating hormone receptor (FSHR). It also exhibits activity on the luteinizing hormone receptor (LH-R) but is inactive on the thyroid-stimulating hormone (TSH) receptor. ADX61623 can be utilized in research on estrogen-dependent diseases.Formula:C19H20N2O3Color and Shape:SolidMolecular weight:324.37ERα degrader 11
CAS:ERα degrader11 (compound B16) is a selective estrogen receptor degrader designed for use as a probe in examining the ER status within ER-positive breast cancer cells.Formula:C28H27F3N2O3Color and Shape:SolidMolecular weight:496.52Estrone acetate
CAS:Estrone acetate (Hogival) is an estrogen derivative and an activator of estrogen receptors (ER). This compound can enhance breast development, stimulate the secretion of pituitary prolactin, and induce both the proliferation and activation of lactotrophs, evidenced by the reduction in prolactin storage granule size and the increase in the volume density of the rough endoplasmic reticulum and Golgi apparatus. Estrone acetate holds potential for endocrinological research and for investigating the mechanisms by which estrogen influences pituitary function, prolactin regulation, and breast tumor models.Formula:C20H24O3Color and Shape:SolidMolecular weight:312.403ORIC-101
CAS:ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.Formula:C34H47NO2Purity:98%Color and Shape:SolidMolecular weight:501.74Pentomone
CAS:Pentomone (LY-113935) is an anti-androgen compound that acts as a prostate growth inhibitor.Formula:C24H26O5Color and Shape:SolidMolecular weight:394.46Estrogen receptor antagonist 4
CAS:Estrogen receptor antagonist 4 blocks ER, impacting cell growth and cancer research potential.Formula:C23H29BF4N4O2Color and Shape:SolidMolecular weight:480.3122-Hydroxy mifepristone
CAS:22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.Formula:C29H35NO3Color and Shape:SolidMolecular weight:445.59
