RAAS
RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.
Found 91 products for "RAAS".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Formula:C48H77N13O12Purity:99.36%Color and Shape:SolidMolecular weight:1028.2Ref: TM-T7575L1
2mg34.00€5mg46.00€10mg60.00€1mL*10mM (DMSO)90.00€25mg119.00€50mg192.00€100mg289.00€200mg415.00€Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Formula:C54H101N15O12SPurity:98%Color and Shape:SolidMolecular weight:1184.54Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Formula:C30H23N4O8·KPurity:99.99%Color and Shape:SolidMolecular weight:606.62TRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Formula:C52H74N14O13Color and Shape:SolidMolecular weight:1103.249[Sar1, Ile8]-Angiotensin II TFA
[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.Formula:C48H74F3N13O12Purity:98%Color and Shape:SolidMolecular weight:1082.18Evazarsen sodium
CAS:Evazarsen sodium, an angiotensinogen synthesis inhibitor, possesses antihypertensive properties [1].Formula:C296H414N86O146P20S19Na20Color and Shape:SolidMolecular weight:9201.6TRV120055
CAS:TRV120055 is a Gq-biased agonist with 10x more efficacy on AT1R-Gq than AT1R-βarr2.Formula:C34H54N12O7Molecular weight:742.883Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Formula:C42H55F3N8O10Purity:98%Color and Shape:SolidMolecular weight:888.93Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Formula:C26H38F3N7O10Purity:98%Color and Shape:SolidMolecular weight:665.62A 779
CAS:A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Formula:C39H60N12O11Purity:98%Color and Shape:SolidMolecular weight:872.97Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formula:C24H37N7O8Purity:98%Color and Shape:SolidMolecular weight:551.59PRO20
PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.Color and Shape:Odour SolidCGP-42112 acetate
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.Formula:C54H73N13O13Purity:99.06% - 99.92%Color and Shape:SolidMolecular weight:1112.24Ref: TM-T14939L
1mg93.00€5mg279.00€10mg403.00€1mL*10mM (DMSO)622.00€25mg623.00€50mg837.00€100mg1,108.00€200mg1,504.00€Aliskiren-D6 hydrochloride
CAS:Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).Formula:C30H54ClN3O6Purity:98%Color and Shape:SolidMolecular weight:594.26[Sar1, Ile8]-Angiotensin II
CAS:[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Formula:C46H73N13O10Purity:98%Color and Shape:SolidMolecular weight:968.15Angiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Formula:C78H125N25O23Color and Shape:SolidMolecular weight:1780.98Losartan (D4 Carboxylic Acid)
CAS:Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.Formula:C22H21ClN6O2Purity:98%Color and Shape:SolidMolecular weight:440.919PD 123319 ditrifluoroacetate
CAS:PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.Formula:C35H34F6N4O7Purity:98%Color and Shape:White SolidMolecular weight:736.66Valsartan-D9
CAS:Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.Formula:C24H29N5O3Purity:98%Color and Shape:SolidMolecular weight:444.574Spirapril hydrochloride
CAS:Spirapril hydrochloride (SCH 33844 hydrochloride) is a potent angiotensin converting enzyme inhibitor with antihypertensive activity that competitively blocks the conversion of angiotensin I to angiotensin II, functions as an orally active proagent of spiraprilat, and is extensively utilized in cardiovascular research focused on hypertension and congestive heart failure pathophysiology and therapeutic intervention.Formula:C22H31ClN2O5S2Purity:99.78%Molecular weight:503.07
![[Sar1, Ile8]-Angiotensin II acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT7575L1.webp&w=3840&q=75)
![[Sar1, Ile8]-Angiotensin II](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT7575.webp&w=3840&q=75)
