RAAS
RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.
Found 95 products for "RAAS".
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Aclerastide
CAS:Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.Formula:C42H64N12O11Color and Shape:SolidMolecular weight:913.03TRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Formula:C52H74N14O13Color and Shape:SolidMolecular weight:1103.249Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Formula:C26H38F3N7O10Purity:98%Color and Shape:SolidMolecular weight:665.62Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Formula:C54H101N15O12SPurity:98%Color and Shape:SolidMolecular weight:1184.54Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Formula:C30H23N4O8·KPurity:99.99%Color and Shape:SolidMolecular weight:606.62Brain Natriuretic Peptide (1-32), rat
CAS:Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.Formula:C146H239N47O44S3Purity:98%Color and Shape:SolidMolecular weight:3452.94PRO20
PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.Color and Shape:Odour SolidRenin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Formula:C90H120N22O16SColor and Shape:SolidMolecular weight:1798.15Evazarsen sodium
CAS:Evazarsen sodium, an angiotensinogen synthesis inhibitor, possesses antihypertensive properties [1].Formula:C296H414N86O146P20S19Na20Color and Shape:SolidMolecular weight:9201.6A 779
CAS:A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Formula:C39H60N12O11Purity:98%Color and Shape:SolidMolecular weight:872.97CGP-42112 acetate
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.Formula:C54H73N13O13Purity:99.92% - 99.94%Color and Shape:SolidMolecular weight:1112.24Ref: TM-T14939L
1mg55.00€5mg167.00€10mg241.00€25mg374.00€1mL*10mM (DMSO)374.00€50mg504.00€100mg665.00€TRV120055
CAS:TRV120055 is a Gq-biased agonist with 10x more efficacy on AT1R-Gq than AT1R-βarr2.Formula:C34H54N12O7Molecular weight:742.883Angiotensin II (5-8), human
CAS:Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin IIFormula:C26H36N6O5Purity:98%Color and Shape:SolidMolecular weight:512.6Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formula:C24H37N7O8Purity:98%Color and Shape:SolidMolecular weight:551.59Alunacedase alfa
CAS:Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.Purity:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Color and Shape:LiquidMolecular weight:85.03 kDaAngiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Formula:C78H125N25O23Color and Shape:SolidMolecular weight:1780.98Losartan (D4 Carboxylic Acid)
CAS:Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.Formula:C22H21ClN6O2Purity:98%Color and Shape:SolidMolecular weight:440.919Olmesartan-D4
CAS:Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.Formula:C24H26N6O3Purity:98%Color and Shape:SolidMolecular weight:450.526Angiotensin II 5-valine
CAS:ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.Formula:C49H69N13O12Purity:98%Color and Shape:SolidMolecular weight:N/ASpirapril hydrochloride
CAS:Spirapril hydrochloride (SCH 33844 hydrochloride) is a potent angiotensin converting enzyme inhibitor with antihypertensive activity that competitively blocks the conversion of angiotensin I to angiotensin II, functions as an orally active proagent of spiraprilat, and is extensively utilized in cardiovascular research focused on hypertension and congestive heart failure pathophysiology and therapeutic intervention.Formula:C22H31ClN2O5S2Purity:99.78%Color and Shape:White SolidMolecular weight:503.07
