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RAAS

RAAS

RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.

Found 86 products of "RAAS"

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  • Handle region peptide, rat

    CAS:
    <p>Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.</p>
    Formula:C54H101N15O12S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1184.54
  • Azilsartan Medoxomil Potassium

    CAS:
    <p>Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.</p>
    Formula:C30H23N4O8·K
    Purity:98.72%
    Color and Shape:Solid
    Molecular weight:606.62
  • Aclerastide

    CAS:
    <p>Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.</p>
    Formula:C42H64N12O11
    Color and Shape:Solid
    Molecular weight:913.03
  • Brain Natriuretic Peptide (1-32), rat

    CAS:
    <p>Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.</p>
    Formula:C146H239N47O44S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3452.94
  • PRO20


    <p>PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.</p>
    Color and Shape:Odour Solid
  • Tetrahydro Aldosterone

    CAS:
    <p>Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.</p>
    Formula:C21H32O5
    Color and Shape:Solid
    Molecular weight:364.48
  • Angiotensin II (1-4), human

    CAS:
    <p>Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.</p>
    Formula:C24H37N7O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:551.59
  • Angiotensin II (1-4), human TFA


    <p>Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.</p>
    Formula:C26H38F3N7O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:665.62
  • BIBS 39

    CAS:
    <p>BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.</p>
    Formula:C32H36N4O3
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:524.65
  • A 779

    CAS:
    <p>A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.</p>
    Formula:C39H60N12O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:872.97
  • C-Type Natriuretic Peptide (1-53), human

    CAS:
    <p>CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.</p>
    Formula:C251H417N81O71S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:5801.77
  • Angiotensin amide

    CAS:
    <p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>
    Formula:C49H70N14O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1031.17
  • [Sar1, Ile8]-Angiotensin II

    CAS:
    <p>[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.</p>
    Formula:C46H73N13O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:968.15
  • Losartan (D4 Carboxylic Acid)

    CAS:
    <p>Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.</p>
    Formula:C22H21ClN6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:440.92
  • Angiotensin II (3-8), human

    CAS:
    <p>Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.</p>
    Color and Shape:Solid
  • PD 123319 ditrifluoroacetate

    CAS:
    <p>PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.</p>
    Formula:C35H34F6N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:736.66
  • Candesartan-d4

    CAS:
    <p>Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.</p>
    Formula:C24H20N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:444.48
  • Olmesartan-d4

    CAS:
    <p>Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.</p>
    Formula:C24H26N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:450.53
  • Valsartan-d9

    CAS:
    <p>Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension &amp; heart failure.</p>
    Formula:C24H29N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:444.57
  • Azilsartan-d5

    CAS:
    <p>Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.</p>
    Formula:C25H20N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.48