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RAAS

RAAS

RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.

Found 87 products of "RAAS"

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  • FPL-62129

    CAS:
    <p>FPL-62129 is a calcium channel antagonist and a novel angiotensin-converting enzyme inhibitor with vasodilator activity for the study of cardiovascular disease.</p>
    Formula:C20H19ClF5NO4
    Purity:98.27% - 99.34%
    Color and Shape:Solid
    Molecular weight:467.81
  • Buloxibutid

    CAS:
    <p>Buloxibutid: a novel AT2 receptor agonist, Ki=0.4 nM (AT2), 10 μM (AT1).</p>
    Formula:C23H29N3O4S2
    Purity:97.68% - 98.58%
    Color and Shape:Solid
    Molecular weight:475.62
  • Terlakiren

    CAS:
    <p>Terlakiren (CP-80,794) is a renin inhibitor that inhibits the potency of human renin and can be used to study neurological disorders of the hypertensive type.</p>
    Formula:C31H48N4O7S
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:620.8
  • ACT 178882

    CAS:
    <p>ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).</p>
    Formula:C33H38Cl3N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:647.03
  • KR31173

    CAS:
    <p>KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. When labeled with the 11C isotope, KR31173 can be used as a tracer for positron emission tomography (PET). In mice, KR31173 exhibits favorable biodistribution and pharmacological characteristics. It selectively binds to organs in CD-1 mice known to have a high density of AT1 angiotensin receptors.</p>
    Formula:C31H30N8O2
    Color and Shape:Solid
    Molecular weight:546.62
  • L162389

    CAS:
    <p>L162389 is an angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor and stimulates the conversion of phosphatidylinositol.</p>
    Formula:C31H38N4O4S
    Purity:99.11% - 99.57%
    Color and Shape:Solid
    Molecular weight:562.72
  • ZD 7155 hydrochloride

    CAS:
    <p>ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.</p>
    Formula:C26H27ClN6O
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:474.98