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Glucocorticoid Receptor

Glucocorticoid Receptor

The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.

Found 153 products of "Glucocorticoid Receptor"

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  • Fluocinolone (Acetonide)

    CAS:
    <p>Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.</p>
    Formula:C24H30F2O6
    Purity:99.29% - 99.82%
    Color and Shape:Crystals From Acetone & Hexane Solid
    Molecular weight:452.49
  • Clobetasol propionate

    CAS:
    <p>Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated</p>
    Formula:C25H32ClFO5
    Purity:99.41%
    Color and Shape:White Crystalline Powder
    Molecular weight:466.97
  • Amcinonide

    CAS:
    <p>Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.</p>
    Formula:C28H35FO7
    Purity:98.33% - 99.62%
    Color and Shape:Solid
    Molecular weight:502.57
  • Dexamethasone

    CAS:
    <p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>
    Formula:C22H29FO5
    Purity:98% - 99.91%
    Color and Shape:Crystals From Ether (Ntp 1992)
    Molecular weight:392.46
  • Hydrocortisone

    CAS:
    <p>Hydrocortisone is a synthetic glucocorticoid that aids in metabolism, immunity, and inflammation control.</p>
    Formula:C21H30O5
    Purity:98.4% - 99.95%
    Color and Shape:Plates From Alc Or Iso-Propyl Alc Solid
    Molecular weight:362.46
  • Mifepristone

    CAS:
    <p>Mifepristone (C-1073) is a progesterone-receptor (IC50=0.2 nM) and glucocorticoid-receptor antagonist (IC50=2.6 nM). High-Quality, Low-Cost!</p>
    Formula:C29H35NO2
    Purity:98.9% - ≥95%
    Color and Shape:Pale Yellow Solid
    Molecular weight:429.59
  • Mirodenafil

    CAS:
    <p>Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.</p>
    Formula:C26H37N5O5S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:531.67
  • Prednisolone acetate


    <p>Prednisolone acetate (Omnipred) is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.</p>
    Formula:C23H30O6
    Purity:98.26% - 98.85%
    Color and Shape:White Crystalline Powder
    Molecular weight:402.48
  • Nimodipine

    CAS:
    <p>Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.</p>
    Formula:C21H26N2O7
    Purity:99.64% - 99.79%
    Color and Shape:Solid
    Molecular weight:418.44
  • Dexamethasone acetate

    CAS:
    <p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>
    Formula:C24H31FO6
    Purity:99.22% - 99.65%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:434.50
  • GW-870086

    CAS:
    <p>GW-870086 is an effective anti-inflammatory agent.</p>
    Formula:C31H39F2NO6
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:559.64
  • Esaxerenone

    CAS:
    <p>Esaxerenone (XL-550) is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor.</p>
    Formula:C22H21F3N2O4S
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:466.47
  • Hydrocortisone acetate

    CAS:
    <p>Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive</p>
    Formula:C23H32O6
    Purity:98.89% - 99.22%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:404.5
  • Miricorilant

    CAS:
    <p>Miricorilant (CORT 118335) is a glucocorticoid receptor modulator for the study of digestive and metabolic disorders.</p>
    Formula:C24H23F3N2O2
    Purity:98.75%
    Color and Shape:Solid
    Molecular weight:428.45
  • Prednicarbate

    CAS:
    <p>Prednicarbate (Hoe 777), a corticosteroid, has antipruritic, anti-inflammatory effects, reduces lymphocytes, and inhibits vasodilators.</p>
    Formula:C27H36O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:488.57
  • AL-438

    CAS:
    <p>AL-438 is a non-steroidal selective glucocorticoid receptor modulator.</p>
    Formula:C23H25NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:347.45
  • EX-A5386

    CAS:
    <p>EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50&lt;100nM.</p>
    Formula:C29H27FN4O2
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:482.55
  • Triamcinolone Benetonide

    CAS:
    <p>Triamcinolone benetonide is a synthetic glucocorticoid corticosteroid exhibiting potent anti-inflammatory properties.</p>
    Formula:C35H42FNO8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:623.71
  • Deacylcortivazol

    CAS:
    <p>Deacylcortivazol is a potent glucocorticoid that inhibits growth in glucocorticoid-resistant leukemia cells without receptor mediation.</p>
    Formula:C30H36N2O4
    Color and Shape:Solid
    Molecular weight:488.62
  • Ocedurenone

    CAS:
    <p>Ocedurenone, a corticosteroid receptor antagonist, is a compound utilized in the investigation of kidney disease (WO2018054357, compound I).</p>
    Formula:C28H30ClN5O2
    Color and Shape:Solid
    Molecular weight:504.03