Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.
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Fluorometholone Acetate
CAS:3801-06-7
Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive …
Formula:
C24H31FO5
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
418.5
Ref: TM-T6503
| 25mg | 46.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 86.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mirodenafil dihydrochloride
CAS:862189-96-6
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
Formula:
C26H39Cl2N5O5S
Purity:
99.27% - 99.64%
Color and Shape:
Solid
Molecular weight:
604.59
Ref: TM-TQ0126
| 5mg | 36.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 129.00 € | ||
| 100mg | 199.00 € | ||
| 500mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Fludrocortisone acetate
CAS:514-36-3
Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the …
Formula:
C23H31FO6
Purity:
96.92% - 98.03%
Color and Shape:
Crystalline Solid
Molecular weight:
422.49
Ref: TM-T1666
| 100mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Vamorolone
CAS:13209-41-1
Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and …
Formula:
C22H28O4
Purity:
98.04%
Color and Shape:
Solid
Molecular weight:
356.46
Ref: TM-T17217
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 435.00 € | ||
| 200mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Beclometasone
CAS:4419-39-0
Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent …
Formula:
C22H29ClO5
Purity:
99.41% - 99.68%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
408.92
Ref: TM-T8777
| 1ml | 54.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Finerenone
CAS:1050477-31-0
Finerenone (BAY-948862) is a selective and orally nonsteroidal antagonist of the mineralocorticoid receptor (MR). Cost …
Formula:
C21H22N4O3
Purity:
99.45% - 99.72%
Color and Shape:
Solid
Molecular weight:
378.42
Ref: TM-T21395
| 1mg | 37.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 348.00 € | ||
| 100mg | 555.00 € | ||
| 200mg | 630.00 € | ||
| 500mg | 924.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Velsecorat
CAS:1196509-60-0
Velsecorat (AZD7594) is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).
Formula:
C32H32F2N4O6
Purity:
99.35%
Color and Shape:
Solid
Molecular weight:
606.62
Ref: TM-TQ0225
| 1mg | 58.00 € | ||
| 2mg | 84.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 786.00 € | ||
| 1mL*10mM (DMSO) | 171.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Corticosterone
CAS:50-22-6
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is …
Formula:
C21H30O4
Purity:
97.25% - ≥95%
Color and Shape:
Solid
Molecular weight:
346.46
Ref: TM-T0948L
| 50mg | 53.00 € | ||
| 100mg | 67.00 € | ||
| 200mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ciclesonide
CAS:126544-47-6
Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.
Formula:
C32H44O7
Purity:
100% - 99.94%
Color and Shape:
Solid
Molecular weight:
540.69
Ref: TM-T2526
| 10mg | 52.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 125.00 € | ||
| 100mg | 180.00 € | ||
| 500mg | 446.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Fluocinonide
CAS:356-12-7
Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin …
Formula:
C26H32F2O7
Purity:
100% - 99.51%
Color and Shape:
Solid
Molecular weight:
494.52
Ref: TM-T6502
| 25mg | 39.00 € | ||
| 50mg | 50.00 € | ||
| 100mg | 71.00 € | ||
| 200mg | 105.00 € | ||
| 500mg | 204.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD9977
CAS:1850385-64-6
AZD9977 is a novel, selective modulator of mineralocorticoid receptor .
Formula:
C20H18FN3O5
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
399.37
Ref: TM-T9022
| 1mg | 60.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 707.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Fluticasone furoate
CAS:397864-44-7
Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.
Formula:
C27H29F3O6S
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
538.58
Ref: TM-T21404
| 4g | 2,663.00 € | ||
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 134.00 € | ||
| 100mg | 183.00 € | ||
| 200mg | 272.00 € | ||
| 500mg | 464.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
GSK9027
CAS:1229096-88-1
GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than …
Formula:
C27H19F4N3O2S
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
525.52
Ref: TM-T22818
| 1mg | 59.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 198.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 600.00 € | ||
| 100mg | 828.00 € | ||
| 500mg | 1,663.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Glucocorticoid receptor agonist-1
CAS:2166375-82-0
Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM[1].
Formula:
C35H39NO6
Purity:
99.51%
Color and Shape:
Liquid
Molecular weight:
569.69
Ref: TM-T37908
| 1mg | 210.00 € | ||
| 5mg | 525.00 € | ||
| 10mg | 737.00 € | ||
| 25mg | 1,142.00 € | ||
| 50mg | 1,551.00 € | ||
| 100mg | 2,098.00 € | ||
| 500mg | 4,194.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
AZD9567
CAS:1893415-00-3
AZD9567: potent, selective SGRM, oral, IC50=3.8nM, effective in SCW joint inflammation.
Formula:
C27H28F2N4O3
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
494.53
Ref: TM-T14386
| 1mg | 198.00 € | ||
| 5mg | 503.00 € | ||
| 10mg | 724.00 € | ||
| 25mg | 1,103.00 € | ||
| 50mg | 1,476.00 € | ||
| 100mg | 1,977.00 € | ||
| 1mL*10mM (DMSO) | 560.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Dexamethasone palmitate
CAS:14899-36-6
DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist …
Formula:
C38H59FO6
Purity:
98.08%
Color and Shape:
Solid
Molecular weight:
630.87
Ref: TM-T15102
| 10mg | 49.00 € | ||
| 25mg | 71.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 150.00 € | ||
| 200mg | 216.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
HP210
CAS:728039-52-9
HP210, a selective glucocorticoid receptor modulator (SGRM), can suppress IL-1β and IL-6 mRNA expression, suggesting …
Formula:
C22H19N3O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
421.54
Ref: TM-T78073
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
N-Demethyl Mifepristone
CAS:104004-96-8
N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for …
Formula:
C28H33NO2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
415.57
Ref: TM-T80652
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
Cort108297
CAS:1018679-79-2
Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.
Formula:
C26H25F4N3O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
535.55
Ref: TM-T15000
| 1mg | 269.00 € | ||
| 5mg | 611.00 € | ||
| 10mg | 887.00 € | ||
| 25mg | 1,384.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,684.00 € | ||
| 1mL*10mM (DMSO) | 743.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
Flunisolide
CAS:3385-03-3
Flunisolide (Rhinalar) is a synthetic corticosteroid with anti-inflammatory and antiallergic properties.
Formula:
C24H31FO6
Purity:
98% - 99.96%
Color and Shape:
Solid
Molecular weight:
434.5
Ref: TM-T1573
| 100mg | Discontinued | Request information |
