Androgen Receptor
The androgen receptor (AR) is a nuclear hormone receptor that is activated by binding to androgens, such as testosterone and dihydrotestosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, as well as in the regulation of several physiological processes, including muscle growth, libido, and bone density. Androgen receptor inhibitors are widely studied in the context of prostate cancer, where AR signaling is often upregulated. At CymitQuimica, we offer a range of high-quality androgen receptor modulators to support your research in endocrinology, cancer biology, and hormone regulation.
Found 229 products of "Androgen Receptor"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
AR antagonist 6
CAS:AR antagonist 6 (compound 6i), a diphenyl ether androgen receptor (AR) antagonist, binds to the AR with an affinity of 120 nM. It demonstrates low toxicity and effective in vitro activity in the golden Syrian hamster ear model. [19] [1]Formula:C16H12F3NO2Color and Shape:SolidMolecular weight:307.27Procymidone
CAS:Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonistFormula:C13H11Cl2NO2Purity:99.86%Color and Shape:Colorless SolidMolecular weight:284.14JNJ-37654032
CAS:JNJ-37654032: orally active, nonsteroidal SARM. Mixed AR agonist/antagonist. Selective for muscle, grows levator ani, max at 3mg/kg, ED(50) 0.8mg/kg.Formula:C11H7Cl2F3N2OColor and Shape:SolidMolecular weight:311.09Androgen receptor antagonist 4
CAS:Compound AT2 is an AR inhibitor with anticancer effects, blocking DHT action and AR nuclear translocation (IC50=0.15μM).Formula:C22H18ClNColor and Shape:SolidMolecular weight:331.84Chlormadinone (free base)
CAS:Chlormadinone: synthetic hormone, treats BPH and PCOS, blocks androgen/estrogen, boosts bone cell growth.Formula:C21H27ClO3Color and Shape:SolidMolecular weight:362.89Bifluranol
CAS:Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostaticFormula:C17H18F2O2Purity:99.86%Color and Shape:SolidMolecular weight:292.32Gumelutamide
CAS:Gumelutamide, a tetrahydropyridopyrimidine compound, functions as both an antiandrogen and an antineoplastic agent by acting as an androgen antagonist.Formula:C22H21ClN6OColor and Shape:SolidMolecular weight:420.89AZD3514
CAS:AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
Formula:C25H32F3N7O2Purity:98.09%Color and Shape:SolidMolecular weight:519.56Honokiol DCA
CAS:Honokiol DCA inhibits DRP1, enhances respiration via mitochondrial repair, and is active against Vemurafenib-resistant melanoma.Formula:C22H18Cl4O4Color and Shape:SolidMolecular weight:488.19Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formula:C15H16Cl3N3O2Purity:99.75% - 99.79%Color and Shape:Colorless SolidMolecular weight:376.67LG-121071
CAS:LG-121071: oral SARM, high-affinity AR full agonist, Ki=17 nM.Formula:C15H15F3N2OPurity:98%Color and Shape:SolidMolecular weight:296.29AR antagonist 5
CAS:Compound 30a, known as AR Antagonist 5, is a selective androgen receptor (AR) antagonist that demonstrates an IC 50 value of 134.8 nM. It exhibits favorable pharmacokinetic properties, characterized by high skin exposure and low plasma exposure [1].Formula:C23H21F3N6O2Color and Shape:SolidMolecular weight:470.45(R)-Bicalutamide
CAS:(R)-Bicalutamide, an AR antagonist with antitumor properties, is crucial in prostate cancer research.Formula:C18H14F4N2O4SColor and Shape:SolidMolecular weight:430.37AR antagonist 2
CAS:AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).Formula:C22H17ClFN5O2SColor and Shape:SolidMolecular weight:469.92Bromopropylate
CAS:Bromopropylate is an insecticide. Bromopropylate is the active substance in fumigant strips for mites.Formula:C17H16Br2O3Purity:98%Color and Shape:White Crystalline Solid Yellowish CrystalsMolecular weight:428.11S-40503
CAS:S-40503 is an investigational selective androgen receptor modulator (SARM).Formula:C15H23N3O3Color and Shape:SolidMolecular weight:293.36Ralaniten
CAS:Ralaniten (EPI-002), a potent AR-NTD antagonist, inhibits AR with IC50 of 7.4 μM, for CRPC study.Formula:C21H27ClO5Purity:99.96%Color and Shape:SolidMolecular weight:394.89Ref: TM-T28502
1mg40.00€5mg88.00€10mg126.00€25mg250.00€50mg393.00€100mg628.00€200mg879.00€1mL*10mM (DMSO)87.00€Androgen receptor antagonist 1
CAS:Androgen receptor antagonist 1, an oral full AR antagonist (IC50 59 nM), for PROTAC synthesis, reducing AR protein by 24–47% in LNCaP cells at 1–10 μM.Formula:C21H25ClN4O3Purity:99.054%Color and Shape:SolidMolecular weight:416.9RU 58642
CAS:RU 58642 is an effective systemic antiandrogen for androgen-dependent disorders.Formula:C15H11F3N4O2Purity:98%Color and Shape:SolidMolecular weight:336.27Cyprodinil
CAS:Cyprodinil is a fungicide blocking methionine synthesis in fungi and hinders B. cinerea, P. herpotrichoides, H. oryzae growth; it's also an AR agonist.Formula:C14H15N3Color and Shape:SolidMolecular weight:225.29
