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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 444 products of "NF-κB"

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  • Specnuezhenide

    CAS:
    <p>Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.</p>
    Formula:C31H42O17
    Purity:98% - 99.93%
    Color and Shape:Solid
    Molecular weight:686.66
  • Isoquercetin

    CAS:
    <p>1.</p>
    Formula:C21H20O12
    Purity:98.08% - 99.76%
    Color and Shape:Solid
    Molecular weight:464.38
  • WITHAFERIN A

    CAS:
    <p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>
    Formula:C28H38O6
    Purity:97.41% - 99.99%
    Color and Shape:Solid
    Molecular weight:470.6
  • Ginsenoside Rd

    CAS:
    <p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>
    Formula:C48H82O18
    Purity:99.13% - 99.92%
    Color and Shape:Solid
    Molecular weight:947.15
  • Dehydroevodiamine

    CAS:
    <p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>
    Formula:C19H15N3O
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:301.34
  • Dauricine

    CAS:
    <p>1.</p>
    Formula:C38H44N2O6
    Purity:99.24% - 99.75%
    Color and Shape:White Powder
    Molecular weight:624.77
  • Dendrophenol

    CAS:
    <p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>
    Formula:C17H20O5
    Purity:98.2% - 99.36%
    Color and Shape:Solid
    Molecular weight:304.34
  • Tizoxanide

    CAS:
    <p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>
    Formula:C10H7N3O4S
    Purity:98.89% - 99.28%
    Color and Shape:Solid
    Molecular weight:265.25
  • Diethylmaleate

    CAS:
    <p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>
    Formula:C8H12O4
    Purity:98%
    Color and Shape:Colourless Liquid
    Molecular weight:172.18
  • SC-514

    CAS:
    <p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>
    Formula:C9H8N2OS2
    Purity:99.88% - >99.99%
    Color and Shape:Solid
    Molecular weight:224.3
  • Ac2-26 acetate


    <p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>
    Formula:C141H210N32O44S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3089.43
  • IRAK inhibitor 6

    CAS:
    <p>IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).</p>
    Formula:C20H20N4O3S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46
  • 2-Hydroxychalcone

    CAS:
    <p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>
    Formula:C15H12O2
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:224.25
  • Neochlorogenic acid

    CAS:
    <p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>
    Formula:C16H18O9
    Purity:99.12% - 99.54%
    Color and Shape:White Powder
    Molecular weight:354.31
  • Triacetylresveratrol

    CAS:
    <p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>
    Formula:C20H18O6
    Purity:99.81%
    Color and Shape:Off White Powder
    Molecular weight:354.35
  • AS-2444697

    CAS:
    <p>AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.</p>
    Formula:C19H21ClN6O4
    Purity:97.17%
    Color and Shape:Solid
    Molecular weight:432.86
  • 2,5-Dihydroxyacetophenone

    CAS:
    <p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>
    Formula:C8H8O3
    Purity:99.75%
    Color and Shape:Yellow Powder
    Molecular weight:152.15
  • Phellodendrine

    CAS:
    <p>Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.</p>
    Formula:C20H24NO4
    Purity:98.7% - 99.94%
    Color and Shape:Solid
    Molecular weight:342.41
  • Micheliolide

    CAS:
    <p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>
    Formula:C15H20O3
    Purity:98% - 99.37%
    Color and Shape:Solid
    Molecular weight:248.32
  • Isovitexin

    CAS:
    <p>1.</p>
    Formula:C21H20O10
    Purity:99.79% - 99.97%
    Color and Shape:Solid
    Molecular weight:432.38