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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 445 products of "NF-κB"

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  • Sciadopitysin
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    Sciadopitysin

    CAS:
    <p>Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.</p>
    Formula:C33H24O10
    Purity:98.14% - 99.17%
    Color and Shape:Solid
    Molecular weight:580.54

    Ref: TM-T5S2129

  • HS-1371
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    HS-1371

    CAS:
    <p>HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.</p>
    Formula:C24H24N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:384.47

    Ref: TM-T6815

  • Okanin
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    Okanin

    CAS:
    <p>Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.</p>
    Formula:C15H12O6
    Purity:95.19% - 99.4%
    Color and Shape:Solid
    Molecular weight:288.25

    Ref: TM-TN2008

  • Schisantherin A
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    Schisantherin A

    CAS:
    <p>Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.</p>
    Formula:C30H32O9
    Purity:98% - 99.989
    Color and Shape:Solid
    Molecular weight:536.57

    Ref: TM-T2913

  • Necrostatin 2 racemate
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    Necrostatin 2 racemate

    CAS:
    <p>Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.</p>
    Formula:C13H12ClN3O2
    Purity:98% - 99.5%
    Color and Shape:Solid
    Molecular weight:277.71

    Ref: TM-T7504

  • Esculentoside H
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    Esculentoside H

    CAS:
    <p>Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.</p>
    Formula:C48H76O21
    Purity:98.04% - 99.3%
    Color and Shape:Solid
    Molecular weight:989.1

    Ref: TM-T3S1641

  • Isoliquiritin apioside
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    Isoliquiritin apioside

    CAS:
    <p>Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.</p>
    Formula:C26H30O13
    Purity:98.84% - 99.27%
    Color and Shape:Solid
    Molecular weight:550.51

    Ref: TM-T3860

  • Ginsenoside Re
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    Ginsenoside Re

    CAS:
    <p>Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.</p>
    Formula:C48H82O18
    Purity:99.12% - >99.99%
    Color and Shape:White Powder
    Molecular weight:947.15

    Ref: TM-T2872

  • Suberosin
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    Suberosin

    CAS:
    <p>Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.</p>
    Formula:C15H16O3
    Purity:97.08% - 99.26%
    Color and Shape:Solid
    Molecular weight:244.29

    Ref: TM-T5795

  • NDMC101
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    NDMC101

    CAS:
    <p>NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.</p>
    Formula:C13H9ClFNO2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:265.67

    Ref: TM-T8550

  • IRAK4-IN-1
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    IRAK4-IN-1

    CAS:
    <p>IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.</p>
    Formula:C19H23N5O
    Purity:98.18% - 99.85%
    Color and Shape:Solid
    Molecular weight:337.42

    Ref: TM-T4140

  • BMS-345541 hydrochloride
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    BMS-345541 hydrochloride

    CAS:
    <p>BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).</p>
    Formula:C14H18ClN5
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:291.78

    Ref: TM-T8542

  • IKK 16
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    IKK 16

    CAS:
    <p>IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.</p>
    Formula:C28H29N5OS
    Purity:98.76% - 99.61%
    Color and Shape:Solid
    Molecular weight:483.63

    Ref: TM-T6176

  • GSK2983559 active metabolite
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    GSK2983559 active metabolite

    CAS:
    <p>GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.</p>
    Formula:C21H22N4O4S2
    Purity:97.07% - 99.57%
    Color and Shape:Solid
    Molecular weight:458.55

    Ref: TM-T5401

  • NF-κΒ activator 2
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    NF-κΒ activator 2

    CAS:
    <p>NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.</p>
    Formula:C16H11FN2O3
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:298.27

    Ref: TM-T39924

  • Eurycomalactone
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    Eurycomalactone

    CAS:
    <p>Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.</p>
    Formula:C19H24O6
    Purity:99.48% - 99.87%
    Color and Shape:Solid
    Molecular weight:348.39

    Ref: TM-TN1637

  • JSH-23
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    JSH-23

    CAS:
    <p>JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.</p>
    Formula:C16H20N2
    Purity:98.03% - 99.67%
    Color and Shape:Solid
    Molecular weight:240.34

    Ref: TM-T1930

  • GS143
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    GS143

    CAS:
    <p>GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.</p>
    Formula:C28H19FN2O4
    Purity:97.67%
    Color and Shape:Solid
    Molecular weight:466.46

    Ref: TM-T25465

  • Isodeoxyelephantopin
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    Isodeoxyelephantopin

    CAS:
    <p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>
    Formula:C19H20O6
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:344.36

    Ref: TM-TN1141

  • IKKγ NBD Inhibitory Peptide acetate
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    IKKγ NBD Inhibitory Peptide acetate

    <p>IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.</p>
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:N/A

    Ref: TM-TP1615L