NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 445 products of "NF-κB"
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PS 1145 dihydrochloride
CAS:<p>IκB kinase (IKK) inhibitor</p>Formula:C17H13Cl3N4OPurity:98%Color and Shape:SolidMolecular weight:395.67Nasunin
CAS:<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Formula:C42H47ClO23Color and Shape:SolidMolecular weight:955.26Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Formula:C20H28O6Color and Shape:SolidMolecular weight:364.43NF-κB Signaling Compound Library
<p>A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;</p>Color and Shape:Odour SolidMesalamine impurity P
CAS:<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Formula:C13H11NO6SColor and Shape:SolidMolecular weight:309.30NF-κΒ activator 1
CAS:<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formula:C16H11FN2O2SPurity:99.58%Color and Shape:SolidMolecular weight:314.333-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formula:C30H44O7SColor and Shape:SolidMolecular weight:548.73PROTAC STING degrader-3
<p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>Color and Shape:Odour SolidLemnalol
CAS:<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Formula:C15H24OPurity:98%Color and Shape:SolidMolecular weight:220.35Licoagrochalcone C
CAS:<p>Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.</p>Formula:C21H22O5Color and Shape:SolidMolecular weight:354.4TBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formula:C31H36F2N8O4Color and Shape:SolidMolecular weight:622.678Helenalin
CAS:<p>Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.</p>Formula:C15H18O4Purity:98%Color and Shape:SolidMolecular weight:262.3NF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formula:C62H50N4O4SColor and Shape:SolidMolecular weight:947.15R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Formula:C22H19N3O2S2Color and Shape:SolidMolecular weight:421.54Narlumosbart
CAS:<p>Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].</p>Purity:98%Color and Shape:Liquid(−)-N-Hydroxyapiosporamide
CAS:<p>(−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, serves as an NF-κB inhibitor and demonstrates significant antitumor activity both in vitro and in vivo.</p>Formula:C24H31NO7Purity:98%Color and Shape:SolidMolecular weight:445.5112-Oxo phytodienoic acid
CAS:<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formula:C18H28O3Purity:98%Color and Shape:SolidMolecular weight:292.41OT-551 HCl
CAS:<p>OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular</p>Formula:C13H24ClNO3Purity:99.71%Color and Shape:SolidMolecular weight:277.79IRAK inhibitor 2
CAS:<p>IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.</p>Formula:C17H14N4O2Purity:97.90% - 99.58%Color and Shape:SolidMolecular weight:306.32BIZ 114
CAS:<p>BIZ 114 potently inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and/or treat ophthalmic disorders.</p>Formula:C24H40O3Color and Shape:SolidMolecular weight:376.57
