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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 445 products of "NF-κB"

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  • Micheliolide

    CAS:
    <p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>
    Formula:C15H20O3
    Purity:98% - 99.37%
    Color and Shape:Solid
    Molecular weight:248.32
  • BI-69A11

    CAS:
    <p>BI-69A11 is a dual AKT/NFkB inhibitor, increasing colon cancer cell sensitivity to mda-7/IL-24.</p>
    Formula:C25H16ClN3O2
    Purity:96.97%
    Color and Shape:Solid
    Molecular weight:425.87
  • Isoquercetin

    CAS:
    <p>1.</p>
    Formula:C21H20O12
    Purity:98.08% - 99.76%
    Color and Shape:Solid
    Molecular weight:464.38
  • Licochalcone D

    CAS:
    <p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>
    Formula:C21H22O5
    Purity:99.03% - 99.9%
    Color and Shape:Solid
    Molecular weight:354.4
  • Articaine

    CAS:
    <p>Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-</p>
    Formula:C13H20N2O3S
    Color and Shape:Solid
    Molecular weight:284.37
  • IMM-H007

    CAS:
    <p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>
    Formula:C22H23N5O8
    Purity:97.73%
    Color and Shape:Solid
    Molecular weight:485.45
  • Sulfuretin

    CAS:
    <p>Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.</p>
    Formula:C15H10O5
    Purity:98.91% - 99.86%
    Color and Shape:Solid
    Molecular weight:270.24
  • 2,5-Dihydroxyacetophenone

    CAS:
    <p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>
    Formula:C8H8O3
    Purity:99.75%
    Color and Shape:Yellow Powder
    Molecular weight:152.15
  • Nitidine chloride

    CAS:
    <p>1.</p>
    Formula:C21H18ClNO4
    Purity:96.59% - 98.91%
    Color and Shape:Solid
    Molecular weight:383.82
  • Flaconitine

    CAS:
    <p>Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.</p>
    Formula:C36H49NO12
    Purity:98% - 99.84%
    Color and Shape:Solid
    Molecular weight:687.77
  • Vanillic Acid

    CAS:
    <p>Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.</p>
    Formula:C8H8O4
    Purity:99.82%
    Color and Shape:White Odourless Crystals Or Powder
    Molecular weight:168.15
  • 2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC

    CAS:
    <p>2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.</p>
    Formula:C11H10N2OS
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:218.27
  • BOT-64

    CAS:
    <p>BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole</p>
    Formula:C15H15NO2S
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:273.35
  • 18α-Glycyrrhetinic acid

    CAS:
    <p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>
    Formula:C30H46O4
    Purity:98.54% - 99.68%
    Color and Shape:Solid
    Molecular weight:470.68
  • (E/Z)-IT-603

    CAS:
    <p>(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.</p>
    Formula:C11H9BrN2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:329.17
  • Asperulosidic acid

    CAS:
    <p>Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.</p>
    Formula:C18H24O12
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:432.38
  • BX795

    CAS:
    <p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>
    Formula:C23H26IN7O2S
    Purity:98% - 99.57%
    Color and Shape:Solid
    Molecular weight:591.47
  • Triacetylresveratrol

    CAS:
    <p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>
    Formula:C20H18O6
    Purity:99.81%
    Color and Shape:Off White Powder
    Molecular weight:354.35
  • AS-2444697

    CAS:
    <p>AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.</p>
    Formula:C19H21ClN6O4
    Purity:97.17%
    Color and Shape:Solid
    Molecular weight:432.86
  • Galloylpaeoniflorin

    CAS:
    <p>Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.</p>
    Formula:C30H32O15
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:632.57