
NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 445 products of "NF-κB"
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Micheliolide
CAS:<p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>Formula:C15H20O3Purity:98% - 99.37%Color and Shape:SolidMolecular weight:248.32BI-69A11
CAS:<p>BI-69A11 is a dual AKT/NFkB inhibitor, increasing colon cancer cell sensitivity to mda-7/IL-24.</p>Formula:C25H16ClN3O2Purity:96.97%Color and Shape:SolidMolecular weight:425.87Isoquercetin
CAS:<p>1.</p>Formula:C21H20O12Purity:98.08% - 99.76%Color and Shape:SolidMolecular weight:464.38Licochalcone D
CAS:<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Formula:C21H22O5Purity:99.03% - 99.9%Color and Shape:SolidMolecular weight:354.4Articaine
CAS:<p>Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-</p>Formula:C13H20N2O3SColor and Shape:SolidMolecular weight:284.37IMM-H007
CAS:<p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>Formula:C22H23N5O8Purity:97.73%Color and Shape:SolidMolecular weight:485.45Sulfuretin
CAS:<p>Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.</p>Formula:C15H10O5Purity:98.91% - 99.86%Color and Shape:SolidMolecular weight:270.242,5-Dihydroxyacetophenone
CAS:<p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>Formula:C8H8O3Purity:99.75%Color and Shape:Yellow PowderMolecular weight:152.15Nitidine chloride
CAS:<p>1.</p>Formula:C21H18ClNO4Purity:96.59% - 98.91%Color and Shape:SolidMolecular weight:383.82Flaconitine
CAS:<p>Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.</p>Formula:C36H49NO12Purity:98% - 99.84%Color and Shape:SolidMolecular weight:687.77Vanillic Acid
CAS:<p>Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.</p>Formula:C8H8O4Purity:99.82%Color and Shape:White Odourless Crystals Or PowderMolecular weight:168.152-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS:<p>2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.</p>Formula:C11H10N2OSPurity:99.48%Color and Shape:SolidMolecular weight:218.27BOT-64
CAS:<p>BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole</p>Formula:C15H15NO2SPurity:99.73%Color and Shape:SolidMolecular weight:273.3518α-Glycyrrhetinic acid
CAS:<p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>Formula:C30H46O4Purity:98.54% - 99.68%Color and Shape:SolidMolecular weight:470.68(E/Z)-IT-603
CAS:<p>(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.</p>Formula:C11H9BrN2O3SPurity:99.35%Color and Shape:SolidMolecular weight:329.17Asperulosidic acid
CAS:<p>Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.</p>Formula:C18H24O12Purity:99.47%Color and Shape:SolidMolecular weight:432.38BX795
CAS:<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Formula:C23H26IN7O2SPurity:98% - 99.57%Color and Shape:SolidMolecular weight:591.47Triacetylresveratrol
CAS:<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35AS-2444697
CAS:<p>AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.</p>Formula:C19H21ClN6O4Purity:97.17%Color and Shape:SolidMolecular weight:432.86Galloylpaeoniflorin
CAS:<p>Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.</p>Formula:C30H32O15Purity:99.82%Color and Shape:SolidMolecular weight:632.57
