NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 398 products of "NF-κB"
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Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFormula:C19H18NO4Purity:98.08% - 99.18%Color and Shape:SolidMolecular weight:324.35OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Formula:C44H70O16Purity:99.46% - ≥95%Color and Shape:SolidMolecular weight:855.02Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purity:99.13% - 99.92%Color and Shape:SolidMolecular weight:947.15Ref: TM-T2878
1mg37.00€5mg71.00€10mg99.00€25mg170.00€50mg260.00€100mg394.00€200mg570.00€1mL*10mM (DMSO)124.00€Zimlovisertib
CAS:Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4).Formula:C18H20FN3O4Purity:98.21%Color and Shape:SolidMolecular weight:361.37Micheliolide
CAS:Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.Formula:C15H20O3Purity:98% - 99.37%Color and Shape:SolidMolecular weight:248.32Ref: TM-T5688
1mg44.00€5mg113.00€10mg177.00€25mg299.00€50mg447.00€100mg623.00€500mg1,305.00€1mL*10mM (DMSO)124.00€Sodium Aescinate
CAS:Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.Formula:C54H83NaO23Purity:95.17%Color and Shape:SolidMolecular weight:1123.21(E/Z)-IT-603
CAS:(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.Formula:C11H9BrN2O3SPurity:99.35%Color and Shape:SolidMolecular weight:329.17Ref: TM-T8799
1mg56.00€5mg119.00€10mg192.00€25mg356.00€50mg565.00€100mg802.00€200mg1,099.00€1mL*10mM (DMSO)133.00€Vanillic Acid
CAS:Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.Formula:C8H8O4Purity:99.82%Color and Shape:White Odourless Crystals Or PowderMolecular weight:168.15Dendrophenol
CAS:Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.Formula:C17H20O5Purity:98.2% - 99.36%Color and Shape:SolidMolecular weight:304.34Ref: TM-T3S1707
1mg99.00€2mg138.00€5mg215.00€10mg319.00€25mg530.00€50mg755.00€100mg1,018.00€1mL*10mM (DMSO)234.00€Flaconitine
CAS:Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.
Formula:C36H49NO12Purity:98% - 99.84%Color and Shape:SolidMolecular weight:687.77Rubiadin-1-methyl ether
CAS:Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.
Formula:C16H12O4Purity:98.32%Color and Shape:SolidMolecular weight:268.2618α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Formula:C30H46O4Purity:98.54% - 99.68%Color and Shape:SolidMolecular weight:470.682-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS:2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.
Formula:C11H10N2OSPurity:99.48%Color and Shape:SolidMolecular weight:218.27Asperulosidic acid
CAS:Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.Formula:C18H24O12Purity:99.47%Color and Shape:SolidMolecular weight:432.38Ref: TM-TN1410
1mg120.00€2mg170.00€5mg260.00€10mg432.00€25mg708.00€50mg964.00€100mg1,288.00€1mL*10mM (DMSO)286.00€BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFormula:C15H15NO2SPurity:99.73%Color and Shape:SolidMolecular weight:273.35Ref: TM-T8705
1mg50.00€5mg110.00€10mg170.00€25mg323.00€50mg494.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)102.00€Galloylpaeoniflorin
CAS:Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.Formula:C30H32O15Purity:99.82%Color and Shape:SolidMolecular weight:632.57Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:97.79% - >99.99%Color and Shape:Yellow SolidMolecular weight:384.24Ref: TM-T2399
5mg50.00€10mg60.00€25mg75.00€50mg92.00€100mg137.00€200mg213.00€500mg353.00€1mL*10mM (DMSO)50.00€Cyclo(his-pro)
CAS:Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.Formula:C11H14N4O2Purity:99.87%Color and Shape:SolidMolecular weight:234.25Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurity:98.89% - 99.28%Color and Shape:SolidMolecular weight:265.25Triacetylresveratrol
CAS:Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.
Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35
