NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 398 products of "NF-κB"
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Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Formula:C36H56O8Purity:98.55% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:616.83Handelin
CAS:Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.Formula:C32H40O8Purity:99.02% - 99.345%Color and Shape:SolidMolecular weight:552.66Sciadopitysin
CAS:Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.Formula:C33H24O10Purity:98.67% - 99.17%Color and Shape:SolidMolecular weight:580.54Ref: TM-T5S2129
1mg49.00€5mg89.00€10mg154.00€25mg288.00€50mg432.00€100mg620.00€500mg1,279.00€1mL*10mM (DMSO)123.00€HS-1371
CAS:HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.Formula:C24H24N4OPurity:98%Color and Shape:SolidMolecular weight:384.47Okanin
CAS:Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.Formula:C15H12O6Purity:95.19% - 99.4%Color and Shape:SolidMolecular weight:288.25Ref: TM-TN2008
1mg84.00€5mg245.00€10mg295.00€25mg497.00€50mg710.00€100mg964.00€1mL*10mM (DMSO)207.00€Schisantherin A
CAS:Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.Formula:C30H32O9Purity:98% - 99.989Color and Shape:SolidMolecular weight:536.57Esculentoside H
CAS:Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.Formula:C48H76O21Purity:98.04% - 99.3%Color and Shape:SolidMolecular weight:989.1Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51Ginsenoside Re
CAS:Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purity:99.12% - >99.99%Color and Shape:White PowderMolecular weight:947.15Ref: TM-T2872
2mg35.00€5mg50.00€10mg66.00€25mg97.00€50mg145.00€100mg207.00€200mg306.00€1mL*10mM (DMSO)69.00€Suberosin
CAS:Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.Formula:C15H16O3Purity:97.08% - 99.26%Color and Shape:SolidMolecular weight:244.29Ref: TM-T5795
2mg37.00€5mg54.00€10mg93.00€25mg167.00€50mg241.00€100mg359.00€200mg525.00€1mL*10mM (DMSO)56.00€NDMC101
CAS:NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.Formula:C13H9ClFNO2Purity:99.89%Color and Shape:SolidMolecular weight:265.67BMS-345541 hydrochloride
CAS:BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).Formula:C14H18ClN5Purity:99.13%Color and Shape:SolidMolecular weight:291.78Ref: TM-T8542
1mg38.00€2mg50.00€5mg82.00€10mg119.00€25mg212.00€50mg356.00€100mg533.00€1mL*10mM (DMSO)52.00€NF-κΒ activator 2
CAS:NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.Formula:C16H11FN2O3Purity:98.12%Color and Shape:SolidMolecular weight:298.27Ref: TM-T39924
1mg94.00€2mg136.00€5mg226.00€10mg335.00€25mg538.00€50mg730.00€100mg938.00€1mL*10mM (DMSO)249.00€Eurycomalactone
CAS:Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.Formula:C19H24O6Purity:99.48% - 99.87%Color and Shape:SolidMolecular weight:348.39JSH-23
CAS:JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.Formula:C16H20N2Purity:98.03% - 99.67%Color and Shape:SolidMolecular weight:240.34Ref: TM-T1930
1mg40.00€2mg54.00€5mg88.00€10mg113.00€25mg177.00€50mg268.00€100mg408.00€1mL*10mM (DMSO)87.00€GS143
CAS:GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.Formula:C28H19FN2O4Purity:97.67%Color and Shape:SolidMolecular weight:466.46Ref: TM-T25465
2mg35.00€5mg55.00€10mg87.00€25mg161.00€50mg245.00€100mg358.00€200mg520.00€1mL*10mM (DMSO)57.00€Isodeoxyelephantopin
CAS:Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formula:C19H20O6Purity:99.88%Color and Shape:SolidMolecular weight:344.36IKKγ NBD Inhibitory Peptide acetate
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.
Purity:99.15%Color and Shape:SolidMolecular weight:N/ARef: TM-TP1615L
1mg131.00€2mg173.00€5mg255.00€10mg374.00€25mg625.00€50mg890.00€100mg1,206.00€500mg2,422.00€Vamorolone
CAS:Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.Formula:C22H28O4Purity:99.54%Color and Shape:SolidMolecular weight:356.46Ref: TM-T17217
1mg34.00€2mg49.00€5mg74.00€10mg105.00€25mg178.00€50mg281.00€100mg421.00€200mg605.00€1mL*10mM (DMSO)82.00€Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formula:C33H40O19Purity:98.78% - 99.13%Color and Shape:SolidMolecular weight:740.66Polygalasaponin F
CAS:Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.Formula:C53H86O23Purity:98% - 99.83%Color and Shape:SolidMolecular weight:1091.24Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39Triptolide
CAS:Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.Formula:C20H24O6Purity:97.19% - 99.97%Color and Shape:White To Off-White SolidMolecular weight:360.40Ref: TM-T2179
1mg39.00€2mg52.00€5mg95.00€10mg123.00€25mg225.00€50mg315.00€100mg444.00€1mL*10mM (DMSO)75.00€Barlerin
CAS:Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose deprivation-induced injuryFormula:C19H28O12Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:448.42Ref: TM-T5S1632
1mg40.00€2mg52.00€5mg85.00€10mg115.00€25mg245.00€50mg354.00€100mg533.00€1mL*10mM (DMSO)92.00€TBK1/IKKε-IN-5
CAS:TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).Formula:C28H31N7O3Purity:98.77%Color and Shape:SolidMolecular weight:513.59Ref: TM-T7951
1mg88.00€5mg182.00€10mg269.00€25mg429.00€50mg587.00€100mg837.00€200mg1,125.00€1mL*10mM (DMSO)224.00€Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purity:99.87% - ≥95%Color and Shape:SolidMolecular weight:284.31Tyrosol
CAS:Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present mostFormula:C8H10O2Purity:99.24% - 99.86%Color and Shape:SolidMolecular weight:138.16PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47SM-7368
CAS:The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.Formula:C10H5ClN4O5SPurity:99.64%Color and Shape:SolidMolecular weight:328.69Ref: TM-T22115
5mg44.00€10mg71.00€25mg128.00€50mg178.00€100mg268.00€200mg389.00€1mL*10mM (DMSO)52.00€Zimlovisertib
CAS:Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4).Formula:C18H20FN3O4Purity:98.21%Color and Shape:SolidMolecular weight:361.37Tomatidine
CAS:Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.
Formula:C27H45NO2Purity:99.94% - 99.98%Color and Shape:SolidMolecular weight:415.6511-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Ref: TM-TN1182
1mg57.00€5mg130.00€10mg200.00€25mg338.00€50mg497.00€100mg710.00€1mL*10mM (DMSO)133.00€Maslinic acid
CAS:Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.Formula:C30H48O4Purity:98.1% - 99.98%Color and Shape:SolidMolecular weight:472.70Malachite green oxalate
CAS:Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.Formula:C23H25N2·C2HO4C2H2O4Color and Shape:Dark Green Crystals With A Metallic LusterMolecular weight:463.51Sarsasapogenin
CAS:Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.Formula:C27H44O3Purity:90% - 99.73%Color and Shape:White Or Off-Withe PowderMolecular weight:416.64Obtusifolin
CAS:Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.Formula:C16H12O5Purity:99.78% - 99.99%Color and Shape:SolidMolecular weight:284.26Ref: TM-T4S0969
1mg66.00€5mg177.00€10mg264.00€25mg447.00€50mg623.00€100mg883.00€1mL*10mM (DMSO)177.00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purity:98.81% - 99.65%Color and Shape:SolidMolecular weight:624.77Gossypin
CAS:Gossypin exhibits multiple medicinal properties and inhibits NF-kappaB, reducing inflammation, cancer growth, and angiogenesis.Formula:C21H20O13Purity:97.57% - 98.97%Color and Shape:SolidMolecular weight:480.38Aconine
CAS:1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.Formula:C25H41NO9Purity:99.61% - 99.93%Color and Shape:SolidMolecular weight:499.59Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formula:C30H48O6Purity:98.80% - 99.69%Color and Shape:SolidMolecular weight:504.70Delanzomib
CAS:Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Formula:C21H28BN3O5Purity:95.52% - 99.46%Color and Shape:SolidMolecular weight:413.28Ref: TM-T6027
1mg46.00€5mg96.00€10mg140.00€25mg274.00€50mg439.00€100mg660.00€200mg917.00€1mL*10mM (DMSO)95.00€Deoxyelephantopin
CAS:Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.Formula:C19H20O6Purity:99.6% - 99.71%Color and Shape:SolidMolecular weight:344.36Aristolochic acid A
CAS:Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort family of plants.Formula:C17H11NO7Purity:99.85% - 99.97%Color and Shape:Yellow PowderMolecular weight:341.27Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFormula:C9H9NOPurity:98.59% - >99.99%Color and Shape:SolidMolecular weight:147.17GSK-872
CAS:GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity and inhibits kinase activity.
Formula:C19H17N3O2S2Purity:99.87% - 99.94%Color and Shape:SolidMolecular weight:383.49(S)-(+)-Ibuprofen
CAS:(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).Formula:C13H18O2Purity:99.51% - 99.86%Color and Shape:Colourless Crystalline SolidMolecular weight:206.28MnTBAP chloride
CAS:MnTBAP chloride: SOD mimetic, peroxynitrite scavenger, halves SOD-E. coli growth time, anti-inflammatory, may aid CKD research.Formula:C48H25ClMnN4O8Color and Shape:SolidMolecular weight:876.133'-Sialyllactose sodium
CAS:3'-Sialyllactose sodium is a prebiotic with anti-inflammatory activity that maintains immune homeostasis and can be used to study inflammation.Formula:C23H38NNaO19Purity:>99.99%Color and Shape:SolidMolecular weight:655.53Gatralimab
CAS:Gatralimab (anti-CD52 mAb) shows successful lymphocyte depletion & repopulation in Phase 1, supporting its study for relapsing MS.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDa
