NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Sarsasapogenin
CAS:126-19-2
Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.
Formula:
C27H44O3
Purity:
90% - ≥95%
Color and Shape:
White Or Off-Withe Powder
Molecular weight:
416.64
Ref: TM-T2733
| 10mg | 35.00 € | ||
| 25mg | 59.00 € | ||
| 50mg | 82.00 € | ||
| 100mg | 107.00 € | ||
| 500mg | 248.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Obtusifolin
CAS:477-85-0
Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.
Formula:
C16H12O5
Purity:
100% - 99.79%
Color and Shape:
Solid
Molecular weight:
284.26
Ref: TM-T4S0969
| 1mg | 69.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 644.00 € | ||
| 100mg | 912.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Neferine
CAS:2292-16-2
Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.
Formula:
C38H44N2O6
Purity:
98.81% - 99.18%
Color and Shape:
Solid
Molecular weight:
624.77
Ref: TM-T5S1097
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 135.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 323.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Gossypin
CAS:652-78-8
Gossypin exhibits multiple medicinal properties and inhibits NF-kappaB, reducing inflammation, cancer growth, and angiogenesis.
Formula:
C21H20O13
Purity:
98.97%
Color and Shape:
Solid
Molecular weight:
480.38
Ref: TM-TN1712
| 10mg | 135.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 312.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Aconine
CAS:509-20-6
1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.
Formula:
C25H41NO9
Purity:
99.43% - 99.61%
Color and Shape:
Solid
Molecular weight:
499.59
Ref: TM-T4S1881
| 1mg | 52.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 297.00 € | ||
| 50mg | 442.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Madecassic acid
CAS:18449-41-7
Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.
Formula:
C30H48O6
Purity:
99.45% - 99.55%
Color and Shape:
Solid
Molecular weight:
504.7
Ref: TM-T2758
| 5mg | 44.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 160.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Delanzomib
CAS:847499-27-8
Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like …
Formula:
C21H28BN3O5
Purity:
95.52% - 99.46%
Color and Shape:
Solid
Molecular weight:
413.28
Ref: TM-T6027
| 1mg | 50.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 189.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 558.00 € | ||
| 100mg | 767.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Deoxyelephantopin
CAS:29307-03-7
Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.
Formula:
C19H20O6
Purity:
99.6% - 99.69%
Color and Shape:
Solid
Molecular weight:
344.36
Ref: TM-TN1079
| 1mg | 94.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 342.00 € | ||
| 25mg | 553.00 € | ||
| 50mg | 801.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
JH-X-119-01
CAS:2227368-54-7
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.
Formula:
C25H20N6O3
Purity:
97.1%
Color and Shape:
Solid
Molecular weight:
452.46
Ref: TM-T9203
| 1mg | 65.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 207.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 552.00 € | ||
| 100mg | 768.00 € | ||
| 1mL*10mM (DMSO) | 159.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Aristolochic acid A
CAS:313-67-7
Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly …
Formula:
C17H11NO7
Purity:
99.92% - 99.97%
Color and Shape:
Yellow Powder
Molecular weight:
341.27
Ref: TM-T2801
| 10mg | 51.00 € | ||
| 25mg | 65.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 108.00 € | ||
| 500mg | 254.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Indole-3-carbinol
CAS:700-06-1
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB …
Formula:
C9H9NO
Purity:
100% - 97.06%
Color and Shape:
Solid
Molecular weight:
147.17
Ref: TM-T2947
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
(S)-(+)-Ibuprofen
CAS:51146-56-6
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
Formula:
C13H18O2
Purity:
100% - 99.51%
Color and Shape:
Colourless Crystalline Solid
Molecular weight:
206.28
Ref: TM-T0448
| 1g | 41.00 € | ||
| 5g | 83.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Friday 15 Nov 2024
E3330
CAS:136164-66-4
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
Formula:
C21H30O6
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
378.46
Ref: TM-T6823
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 175.00 € | ||
| 50mg | 290.00 € | ||
| 100mg | 419.00 € | ||
| 200mg | 588.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Kamebakaurin
CAS:73981-34-7
Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling …
Formula:
C20H30O5
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
350.45
Ref: TM-TWS1977
| 1mg | 97.00 € | ||
| 5mg | 312.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Armepavine
CAS:524-20-9
Armepavine (R-Armepavine) exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition …
Formula:
C19H23NO3
Purity:
95.00%
Color and Shape:
Solid
Molecular weight:
313.39
Ref: TM-T3775
| 5mg | 259.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
B022
CAS:1202764-53-1
B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury …
Formula:
C19H16ClN5OS
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
397.88
Ref: TM-T14491
| 1mg | 74.00 € | ||
| 5mg | 163.00 € | ||
| 10mg | 231.00 € | ||
| 25mg | 391.00 € | ||
| 50mg | 572.00 € | ||
| 100mg | 734.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
NFATc1-IN-1
CAS:1912422-56-0
NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.
Formula:
C13H8F2INO2
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
375.11
Ref: TM-T61531
| 5mg | 51.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 346.00 € | ||
| 500mg | 807.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Selnoflast
CAS:2260969-36-4
Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of …
Formula:
C20H29N3O3S
Purity:
100% - 99.82%
Color and Shape:
Solid
Molecular weight:
391.53
Ref: TM-T61786
| 1mg | 128.00 € | ||
| 2mg | 180.00 € | ||
| 5mg | 301.00 € | ||
| 10mg | 502.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,548.00 € | ||
| 100mg | 2,546.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
CHPG sodium salt
CAS:1303993-73-8
CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt …
Formula:
C8H7ClNNaO3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
223.59
Ref: TM-T10808
| 5mg | 47.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
RIPK1-IN-9
CAS:2682889-57-0
RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 …
Formula:
C26H25FN6O2
Purity:
98.7%
Color and Shape:
Solid
Molecular weight:
472.51
Ref: TM-T63055
| 1mg | 335.00 € | ||
| 5mg | 804.00 € | ||
| 10mg | 1,110.00 € | ||
| 25mg | 1,654.00 € | ||
| 50mg | 2,224.00 € | ||
| 100mg | 2,989.00 € | ||
| 1mL*10mM (DMSO) | 939.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
