NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Maslinic acid
CAS:4373-41-5
Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.
Formula:
C30H48O4
Purity:
98.93% - 99.8%
Color and Shape:
Solid
Molecular weight:
472.7
Ref: TM-T3772
| 1mg | 35.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 309.00 € | ||
| 100mg | 484.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Malachite green oxalate
CAS:2437-29-8
Malachite green oxalate is a triphenylmethane dye which can be used to detect the release …
Formula:
C23H25N2·C2HO4C2H2O4
Color and Shape:
Dark Green Crystals With A Metallic Luster
Molecular weight:
463.51
Ref: TM-TD0099
| 100mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Sarsasapogenin
CAS:126-19-2
Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.
Formula:
C27H44O3
Purity:
90% - ≥95%
Color and Shape:
White Or Off-Withe Powder
Molecular weight:
416.64
Ref: TM-T2733
| 10mg | 35.00 € | ||
| 25mg | 59.00 € | ||
| 50mg | 82.00 € | ||
| 100mg | 107.00 € | ||
| 500mg | 248.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Obtusifolin
CAS:477-85-0
Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.
Formula:
C16H12O5
Purity:
100% - 99.79%
Color and Shape:
Solid
Molecular weight:
284.26
Ref: TM-T4S0969
| 1mg | 69.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 644.00 € | ||
| 100mg | 912.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Neferine
CAS:2292-16-2
Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.
Formula:
C38H44N2O6
Purity:
98.81% - 99.18%
Color and Shape:
Solid
Molecular weight:
624.77
Ref: TM-T5S1097
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 135.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 323.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Gossypin
CAS:652-78-8
Gossypin exhibits multiple medicinal properties and inhibits NF-kappaB, reducing inflammation, cancer growth, and angiogenesis.
Formula:
C21H20O13
Purity:
98.97%
Color and Shape:
Solid
Molecular weight:
480.38
Ref: TM-TN1712
| 10mg | 135.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 312.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Aconine
CAS:509-20-6
1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.
Formula:
C25H41NO9
Purity:
99.43% - 99.61%
Color and Shape:
Solid
Molecular weight:
499.59
Ref: TM-T4S1881
| 1mg | 52.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 297.00 € | ||
| 50mg | 442.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Madecassic acid
CAS:18449-41-7
Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.
Formula:
C30H48O6
Purity:
99.45% - 99.55%
Color and Shape:
Solid
Molecular weight:
504.7
Ref: TM-T2758
| 5mg | 44.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 160.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Delanzomib
CAS:847499-27-8
Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like …
Formula:
C21H28BN3O5
Purity:
95.52% - 99.46%
Color and Shape:
Solid
Molecular weight:
413.28
Ref: TM-T6027
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 139.00 € | ||
| 25mg | 271.00 € | ||
| 50mg | 435.00 € | ||
| 100mg | 652.00 € | ||
| 200mg | 905.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Deoxyelephantopin
CAS:29307-03-7
Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.
Formula:
C19H20O6
Purity:
99.6% - 99.69%
Color and Shape:
Solid
Molecular weight:
344.36
Ref: TM-TN1079
| 1mg | 94.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 342.00 € | ||
| 25mg | 553.00 € | ||
| 50mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 239.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
JH-X-119-01
CAS:2227368-54-7
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.
Formula:
C25H20N6O3
Purity:
97.1%
Color and Shape:
Solid
Molecular weight:
452.46
Ref: TM-T9203
| 1mg | 65.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 207.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 552.00 € | ||
| 100mg | 768.00 € | ||
| 1mL*10mM (DMSO) | 159.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Aristolochic acid A
CAS:313-67-7
Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly …
Formula:
C17H11NO7
Purity:
99.92% - 99.97%
Color and Shape:
Yellow Powder
Molecular weight:
341.27
Ref: TM-T2801
| 10mg | 51.00 € | ||
| 25mg | 65.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 108.00 € | ||
| 500mg | 254.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Indole-3-carbinol
CAS:700-06-1
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB …
Formula:
C9H9NO
Purity:
100% - 97.06%
Color and Shape:
Solid
Molecular weight:
147.17
Ref: TM-T2947
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
(S)-(+)-Ibuprofen
CAS:51146-56-6
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
Formula:
C13H18O2
Purity:
100% - 99.51%
Color and Shape:
Colourless Crystalline Solid
Molecular weight:
206.28
Ref: TM-T0448
| 1g | 41.00 € | ||
| 5g | 83.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Kamebakaurin
CAS:73981-34-7
Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling …
Formula:
C20H30O5
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
350.45
Ref: TM-TWS1977
| 1mg | 97.00 € | ||
| 5mg | 312.00 € |
Estimated delivery in United States, on Wednesday 15 Jan 2025
E3330
CAS:136164-66-4
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
Formula:
C21H30O6
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
378.46
Ref: TM-T6823
| 1mg | 50.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 494.00 € | ||
| 100mg | 716.00 € | ||
| 200mg | 1,004.00 € | ||
| 500mg | 1,476.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 15 Jan 2025
NF-κB-IN-11
CAS:2768833-35-6
NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and …
Formula:
C19H18O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
326.34
Ref: TM-T79671
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Zharp2-1
CAS:2772600-18-5
Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be …
Formula:
C19H18N3O2PS
Purity:
99.41%
Color and Shape:
Liquid
Molecular weight:
383.4
Ref: TM-T79600
| 5mg | 67.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 479.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Selnoflast
CAS:2260969-36-4
Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of …
Formula:
C20H29N3O3S
Purity:
100% - 99.82%
Color and Shape:
Liquid
Molecular weight:
391.53
Ref: TM-T61786
| 1mg | 128.00 € | ||
| 2mg | 180.00 € | ||
| 5mg | 301.00 € | ||
| 10mg | 502.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,548.00 € | ||
| 100mg | 2,546.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
TRAF-STOP inhibitor 6877002
CAS:433249-94-6
TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.
Formula:
C17H17NO
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
251.32
Ref: TM-T17157
| 10mg | 42.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 140.00 € | ||
| 100mg | To inquire | ||
| 200mg | To inquire | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
