NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Read more
Deoxyelephantopin
CAS:29307-03-7
Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.
Formula:
C19H20O6
Purity:
99.6% - 99.69%
Color and Shape:
Solid
Molecular weight:
344.36
Ref: TM-TN1079
| 1mg | 96.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 349.00 € | ||
| 25mg | 567.00 € | ||
| 50mg | 820.00 € | ||
| 1mL*10mM (DMSO) | 240.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
JH-X-119-01
CAS:2227368-54-7
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.
Formula:
C25H20N6O3
Purity:
97.1%
Color and Shape:
Solid
Molecular weight:
452.46
Ref: TM-T9203
| 1mg | 66.00 € | ||
| 2mg | 96.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 210.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 780.00 € | ||
| 1mL*10mM (DMSO) | 159.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Aristolochic acid A
CAS:313-67-7
Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly …
Formula:
C17H11NO7
Purity:
99.85% - 99.97%
Color and Shape:
Yellow Powder
Molecular weight:
341.27
Ref: TM-T2801
| 10mg | 47.00 € | ||
| 25mg | 60.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 113.00 € | ||
| 500mg | 265.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Indole-3-carbinol
CAS:700-06-1
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB …
Formula:
C9H9NO
Purity:
100% - 97.06%
Color and Shape:
Solid
Molecular weight:
147.17
Ref: TM-T2947
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
(S)-(+)-Ibuprofen
CAS:51146-56-6
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
Formula:
C13H18O2
Purity:
100% - 99.51%
Color and Shape:
Colourless Crystalline Solid
Molecular weight:
206.28
Ref: TM-T0448
| 1g | 42.00 € | ||
| 5g | 85.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 11 Mar 2025
E3330
CAS:136164-66-4
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
Formula:
C21H30O6
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
378.46
Ref: TM-T6823
| 1mg | 50.00 € | ||
| 2mg | 72.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 725.00 € | ||
| 200mg | 1,017.00 € | ||
| 500mg | 1,510.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 7 Apr 2025
Kamebakaurin
CAS:73981-34-7
Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling …
Formula:
C20H30O5
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
350.45
Ref: TM-TWS1977
| 1mg | 99.00 € | ||
| 5mg | 319.00 € | ||
| 10mg | 472.00 € |
Estimated delivery in United States, on Monday 7 Apr 2025
Biricodar dicitrate
CAS:174254-13-8
Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be …
Formula:
C46H57N3O21
Purity:
98.67%
Color and Shape:
Liquid
Molecular weight:
987.95
Ref: TM-T67790
| 1mg | 492.00 € | ||
| 5mg | 1,111.00 € | ||
| 25mg | 1,825.00 € | ||
| 50mg | 2,262.00 € | ||
| 100mg | 2,945.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Zabedosertib
CAS:1931994-81-8
Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.
Formula:
C20H21F3N4O4S
Purity:
98.48%
Color and Shape:
Liquid
Molecular weight:
470.47
Ref: TM-T37076
| 1mg | 43.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 220.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 450.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Lobeglitazone Sulfate
CAS:763108-62-9
Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used …
Formula:
C24H26N4O9S2
Purity:
98.69%
Color and Shape:
Solid
Molecular weight:
578.61
Ref: TM-T27841
| 1mg | 111.00 € | ||
| 5mg | 264.00 € | ||
| 10mg | 424.00 € | ||
| 25mg | 677.00 € | ||
| 50mg | 1,008.00 € | ||
| 100mg | 1,473.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
IMD-catechol
CAS:2928463-39-0
IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.
Formula:
C31H34N6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
538.64
Ref: TM-T72927
| 25mg | 2,015.00 € | ||
| 50mg | 2,642.00 € | ||
| 100mg | 3,515.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
IRAK4-IN-20
CAS:1931994-80-7
IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).
Formula:
C22H25F3N4O3
Purity:
97.32%
Color and Shape:
Liquid
Molecular weight:
450.45
Ref: TM-T62714
| 1mg | 185.00 € | ||
| 5mg | 426.00 € | ||
| 10mg | 627.00 € | ||
| 25mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 487.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
NLRP3-IN-13
CAS:1704638-35-6
NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study …
Formula:
C19H15N3O3S
Purity:
98.82%
Color and Shape:
Liquid
Molecular weight:
365.41
Ref: TM-T73018
| 1mg | 57.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 432.00 € | ||
| 50mg | 655.00 € | ||
| 100mg | 1,035.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
TRAF-STOP inhibitor 6877002
CAS:433249-94-6
TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.
Formula:
C17H17NO
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
251.32
Ref: TM-T17157
| 10mg | 43.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 142.00 € | ||
| 100mg | To inquire | ||
| 200mg | To inquire | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
RIPK1-IN-9
CAS:2682889-57-0
RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 …
Formula:
C26H25FN6O2
Purity:
98.7%
Color and Shape:
Liquid
Molecular weight:
472.51
Ref: TM-T63055
| 1mg | 205.00 € | ||
| 5mg | 495.00 € | ||
| 10mg | 677.00 € | ||
| 25mg | 1,008.00 € | ||
| 50mg | 1,349.00 € | ||
| 100mg | 1,833.00 € | ||
| 200mg | 2,452.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
SZM-1209
CAS:2919801-86-6
SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant …
Formula:
C31H29F5N4O5S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
696.71
Ref: TM-T73382
| 1mg | 183.00 € | ||
| 5mg | 727.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
HS271
CAS:2410393-15-4
HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).
Formula:
C21H24F3N5O2
Purity:
98.12%
Color and Shape:
Solid
Molecular weight:
435.44
Ref: TM-T37082
| 1mg | 62.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 510.00 € | ||
| 100mg | 695.00 € | ||
| 200mg | 937.00 € | ||
| 1mL*10mM (DMSO) | 149.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Bay 65-1942 free base
CAS:600734-02-9
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
Formula:
C22H25N3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
395.45
Ref: TM-T10472L
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
Selnoflast
CAS:2260969-36-4
Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of …
Formula:
C20H29N3O3S
Purity:
100% - 99.82%
Color and Shape:
Liquid
Molecular weight:
391.53
Ref: TM-T61786
| 1mg | 130.00 € | ||
| 2mg | 183.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 512.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,578.00 € | ||
| 100mg | 2,593.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
CID-2858522
CAS:758679-97-9
CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).
Formula:
C28H39N3O3
Purity:
96.11%
Color and Shape:
Solid
Molecular weight:
465.63
Ref: TM-TQ0305
| 1mg | 42.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 224.00 € | ||
| 50mg | 331.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
