NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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CID-2858522
CAS:758679-97-9
CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).
Formula:
C28H39N3O3
Purity:
96.11%
Color and Shape:
Solid
Molecular weight:
465.63
Ref: TM-TQ0305
| 1mg | 41.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 219.00 € | ||
| 50mg | 325.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Penehyclidine hydrochloride
CAS:151937-76-7
Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.
Formula:
C20H30ClNO2
Purity:
99.7%
Color and Shape:
Solid
Molecular weight:
351.91
Ref: TM-T61233
| 1mg | 137.00 € | ||
| 5mg | 331.00 € | ||
| 10mg | 489.00 € | ||
| 25mg | 787.00 € | ||
| 50mg | 1,050.00 € | ||
| 1mL*10mM (DMSO) | 338.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
AP-1/NF-κB activation inhibitor 1
CAS:188936-12-1
AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation …
Formula:
C13H11F3N4O4
Purity:
100% - 99.74%
Color and Shape:
Solid
Molecular weight:
344.25
Ref: TM-T9656
| 1mg | 72.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 215.00 € | ||
| 25mg | 351.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 724.00 € | ||
| 500mg | 1,470.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Zabedosertib
CAS:1931994-81-8
Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.
Formula:
C20H21F3N4O4S
Purity:
98.48%
Color and Shape:
Solid
Molecular weight:
470.47
Ref: TM-T37076
| 1mg | 42.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 442.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
RIP1 kinase inhibitor 6
CAS:2428401-62-9
RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory …
Formula:
C19H18F2N2O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
360.35
Ref: TM-T79043
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
COX-2-IN-32
CAS:2725863-08-9
COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB …
Formula:
C25H24O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
420.45
Ref: TM-T79130
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
BAY32-5915
CAS:1571-30-8
BAY32-5915 is a selective inhibitor of IKKalpha.
Formula:
C10H7NO3
Purity:
96.48% - 97.00%
Color and Shape:
Yellow Crystalline Powder
Molecular weight:
189.17
Ref: TM-T20770
| 100mg | 46.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
NLRP3-IN-10
CAS:2641826-39-1
NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC …
Formula:
C17H14BrFO3
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
365.19
Ref: TM-T61392
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 305.00 € | ||
| 200mg | 454.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
IKK2-IN-4
CAS:354811-10-2
IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 …
Formula:
C12H11N3O2S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
261.3
Ref: TM-T36524
| 1mg | 175.00 € | ||
| 5mg | 776.00 € | ||
| 10mg | 1,049.00 € | ||
| 25mg | 1,561.00 € | ||
| 50mg | 2,109.00 € | ||
| 100mg | 2,775.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Zharp2-1
CAS:2772600-18-5
Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be …
Formula:
C19H18N3O2PS
Purity:
99.41%
Color and Shape:
Solid
Molecular weight:
383.4
Ref: TM-T79600
| 5mg | 67.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 479.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Emlenoflast sodium
CAS:2380032-29-9
Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 …
Formula:
C19H24N4NaO3S
Color and Shape:
Solid
Molecular weight:
411.47
Ref: TM-T9222L
| 2mg | To inquire | ||
| 5mg | 906.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Friday 27 Dec 2024
SP-100030
CAS:154563-54-9
SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.
Formula:
C14H5ClF9N3O
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
437.65
Ref: TM-T24816
| 1mg | 36.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 239.00 € | ||
| 50mg | 371.00 € | ||
| 100mg | 534.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
IMD-biphenylA
CAS:2928463-40-3
IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties …
Formula:
C35H33N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
555.67
Ref: TM-T72869
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
CAY10575
CAS:916985-21-2
CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of …
Formula:
C22H21N3O6S2
Color and Shape:
Solid
Molecular weight:
487.55
Ref: TM-T26957
| 1mg | 92.00 € | ||
| 5mg | 341.00 € | ||
| 10mg | 642.00 € | ||
| 25mg | 1,380.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
IRAK4-IN-20
CAS:1931994-80-7
IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).
Formula:
C22H25F3N4O3
Purity:
97.32%
Color and Shape:
Solid
Molecular weight:
450.45
Ref: TM-T62714
| 1mg | 182.00 € | ||
| 5mg | 417.00 € | ||
| 10mg | 612.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
NF-κB-IN-8
CAS:2924565-59-1
NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression …
Formula:
C24H21N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
399.44
Ref: TM-T74799
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Edasalonexent
CAS:1204317-86-1
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.
Formula:
C31H42N2O3
Purity:
100% - 98.69%
Color and Shape:
Solid
Molecular weight:
490.68
Ref: TM-T15198
| 1mg | 98.00 € | ||
| 2mg | 144.00 € | ||
| 5mg | 233.00 € | ||
| 10mg | 374.00 € | ||
| 25mg | 672.00 € | ||
| 50mg | 1,056.00 € | ||
| 1mL*10mM (DMSO) | 252.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
RIP1 kinase inhibitor 7
CAS:2428401-23-2
RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting …
Formula:
C20H20FN3O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
337.39
Ref: TM-T79044
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
IMD-catechol
CAS:2928463-39-0
IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.
Formula:
C31H34N6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
538.64
Ref: TM-T72927
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Bay 65-1942 hydrochloride
CAS:600734-06-3
Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.
Formula:
C22H26ClN3O4
Color and Shape:
Solid
Molecular weight:
431.91
Ref: TM-T14508
| 2mg | 115.00 € | ||
| 5mg | 185.00 € | ||
| 25mg | 605.00 € | ||
| 50mg | 793.00 € | ||
| 100mg | 1,236.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
