NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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NLRP3-IN-13
CAS:1704638-35-6
NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study …
Formula:
C19H15N3O3S
Purity:
98.82%
Color and Shape:
Solid
Molecular weight:
365.41
Ref: TM-T73018
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 643.00 € | ||
| 100mg | 1,018.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
NF-κB-IN-11
CAS:2768833-35-6
NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and …
Formula:
C19H18O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
326.34
Ref: TM-T79671
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Biricodar dicitrate
CAS:174254-13-8
Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be …
Formula:
C46H57N3O21
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
987.95
Ref: TM-T67790
| 1mg | 493.00 € | ||
| 5mg | 1,086.00 € | ||
| 25mg | 1,825.00 € | ||
| 50mg | 2,209.00 € | ||
| 100mg | 2,890.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
SZM-1209
CAS:2919801-86-6
SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant …
Formula:
C31H29F5N4O5S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
696.71
Ref: TM-T73382
| 1mg | 184.00 € | ||
| 5mg | 726.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Gue1654
CAS:397290-30-1
Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of …
Formula:
C23H17N3OS3
Purity:
98.02% - 98.31%
Color and Shape:
Solid
Molecular weight:
447.6
Ref: TM-T27502
| 1mg | 79.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 239.00 € | ||
| 25mg | 553.00 € | ||
| 50mg | 981.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
IMD-biphenylB
CAS:2928463-41-4
IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.
Formula:
C35H33N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
571.67
Ref: TM-T72870
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
TRAF-STOP inhibitor 6877002
CAS:433249-94-6
TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.
Formula:
C17H17NO
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
251.32
Ref: TM-T17157
| 10mg | 42.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 140.00 € | ||
| 100mg | To inquire | ||
| 200mg | To inquire | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Bay 65-1942 free base
CAS:600734-02-9
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
Formula:
C22H25N3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
395.45
Ref: TM-T10472L
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
GSK319347A
CAS:862812-98-4
GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be …
Formula:
C22H19N3O5S2
Purity:
98.42%
Color and Shape:
Solid
Molecular weight:
469.53
Ref: TM-T15558
| 1mg | 74.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 526.00 € | ||
| 50mg | 893.00 € | ||
| 100mg | 1,204.00 € | ||
| 1mL*10mM (DMSO) | 338.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Lobeglitazone Sulfate
CAS:763108-62-9
Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used …
Formula:
C24H26N4O9S2
Purity:
98.69%
Color and Shape:
Solid
Molecular weight:
578.61
Ref: TM-T27841
| 1mg | 109.00 € | ||
| 5mg | 258.00 € | ||
| 10mg | 414.00 € | ||
| 25mg | 660.00 € | ||
| 50mg | 983.00 € | ||
| 100mg | 1,437.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
SZM679
SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, …
Formula:
C27H18F5N3O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
591.51
Ref: TM-T73511
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
DHMEQ racemate
CAS:287194-38-1
DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.
Formula:
C13H11NO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
261.23
Ref: TM-T11018
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
HS271
CAS:2410393-15-4
HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).
Formula:
C21H24F3N5O2
Purity:
98.12%
Color and Shape:
Solid
Molecular weight:
435.44
Ref: TM-T37082
| 1mg | 60.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 491.00 € | ||
| 100mg | 670.00 € | ||
| 200mg | 902.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
JC124
CAS:1638611-48-9
JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.
Formula:
C17H19ClN2O4S
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
382.86
Ref: TM-T25548
| 1mg | 62.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 524.00 € | ||
| 100mg | 710.00 € | ||
| 200mg | 912.00 € | ||
| 1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
RIP1 kinase inhibitor 5
CAS:2428422-17-5
RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by …
Formula:
C13H17F2NO2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
257.28
Ref: TM-T79042
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
RIP1 kinase inhibitor 4
CAS:2919836-00-1
RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 …
Formula:
C23H23N5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
369.46
Ref: TM-T79041
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
NT-0796
CAS:2272917-13-0
NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery …
Formula:
C23H27N3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
409.48
Ref: TM-T81637
| 1mg | 183.00 € | ||
| 5mg | 456.00 € | ||
| 10mg | 734.00 € | ||
| 25mg | 1,555.00 € | ||
| 50mg | 2,500.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(Rac)-BAY-985
CAS:2101925-20-4
(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.
Formula:
C27H30F3N9O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
553.58
Ref: TM-T12659
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RIPK3-IN-4
CAS:2304617-58-9
RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell …
Formula:
C24H18BrFN4O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
541.39
Ref: TM-T81267
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ADS032
CAS:2757333-37-0
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of …
Formula:
C22H29NO4S
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
403.54
Ref: TM-T79906
| 1mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 541.00 € | ||
| 100mg | 867.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
