NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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CHPG sodium salt
CAS:1303993-73-8
CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt …
Formula:
C8H7ClNNaO3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
223.59
Ref: TM-T10808
| 5mg | 47.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
DHMEQ racemate
CAS:287194-38-1
DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.
Formula:
C13H11NO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
261.23
Ref: TM-T11018
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Gue1654
CAS:397290-30-1
Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of …
Formula:
C23H17N3OS3
Purity:
98.02% - 98.31%
Color and Shape:
Solid
Molecular weight:
447.6
Ref: TM-T27502
| 1mg | 79.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 239.00 € | ||
| 25mg | 553.00 € | ||
| 50mg | 981.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
GSK319347A
CAS:862812-98-4
GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be …
Formula:
C22H19N3O5S2
Purity:
98.42%
Color and Shape:
Solid
Molecular weight:
469.53
Ref: TM-T15558
| 1mg | 74.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 526.00 € | ||
| 50mg | 893.00 € | ||
| 100mg | 1,204.00 € | ||
| 1mL*10mM (DMSO) | 338.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
COX-2-IN-32
CAS:2725863-08-9
COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB …
Formula:
C25H24O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
420.45
Ref: TM-T79130
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Lobeglitazone Sulfate
CAS:763108-62-9
Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used …
Formula:
C24H26N4O9S2
Purity:
98.69%
Color and Shape:
Solid
Molecular weight:
578.61
Ref: TM-T27841
| 1mg | 109.00 € | ||
| 5mg | 258.00 € | ||
| 10mg | 414.00 € | ||
| 25mg | 660.00 € | ||
| 50mg | 983.00 € | ||
| 100mg | 1,437.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
SZM679
SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, …
Formula:
C27H18F5N3O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
591.51
Ref: TM-T73511
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
NFATc1-IN-1
CAS:1912422-56-0
NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.
Formula:
C13H8F2INO2
Purity:
99.64%
Color and Shape:
Liquid
Molecular weight:
375.11
Ref: TM-T61531
| 5mg | 51.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 346.00 € | ||
| 500mg | 807.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
IMD-biphenylB
CAS:2928463-41-4
IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.
Formula:
C35H33N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
571.67
Ref: TM-T72870
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
SP-100030
CAS:154563-54-9
SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.
Formula:
C14H5ClF9N3O
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
437.65
Ref: TM-T24816
| 1mg | 36.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 239.00 € | ||
| 50mg | 371.00 € | ||
| 100mg | 534.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
RIP1 kinase inhibitor 5
CAS:2428422-17-5
RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by …
Formula:
C13H17F2NO2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
257.28
Ref: TM-T79042
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
IKK2-IN-4
CAS:354811-10-2
IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 …
Formula:
C12H11N3O2S
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
261.3
Ref: TM-T36524
| 1mg | 302.00 € | ||
| 5mg | 736.00 € | ||
| 10mg | 1,009.00 € | ||
| 25mg | 1,523.00 € | ||
| 50mg | 2,037.00 € | ||
| 100mg | 2,775.00 € | ||
| 200mg | 3,662.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
RIP1 kinase inhibitor 6
CAS:2428401-62-9
RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory …
Formula:
C19H18F2N2O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
360.35
Ref: TM-T79043
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
AP-1/NF-κB activation inhibitor 1
CAS:188936-12-1
AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation …
Formula:
C13H11F3N4O4
Purity:
100% - 99.74%
Color and Shape:
Liquid
Molecular weight:
344.25
Ref: TM-T9656
| 1mg | 72.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 215.00 € | ||
| 25mg | 351.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 724.00 € | ||
| 500mg | 1,470.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
IRAK4-IN-20
CAS:1931994-80-7
IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).
Formula:
C22H25F3N4O3
Purity:
97.32%
Color and Shape:
Liquid
Molecular weight:
450.45
Ref: TM-T62714
| 1mg | 182.00 € | ||
| 5mg | 417.00 € | ||
| 10mg | 612.00 € | ||
| 25mg | 922.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Biricodar dicitrate
CAS:174254-13-8
Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be …
Formula:
C46H57N3O21
Purity:
98.67%
Color and Shape:
Liquid
Molecular weight:
987.95
Ref: TM-T67790
| 1mg | 493.00 € | ||
| 5mg | 1,086.00 € | ||
| 25mg | 1,825.00 € | ||
| 50mg | 2,209.00 € | ||
| 100mg | 2,890.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Zabedosertib
CAS:1931994-81-8
Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.
Formula:
C20H21F3N4O4S
Purity:
98.48%
Color and Shape:
Liquid
Molecular weight:
470.47
Ref: TM-T37076
| 1mg | 42.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 442.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
RIPK1-IN-4
CAS:1481641-08-0
RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase …
Formula:
C23H23N5O2
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
401.46
Ref: TM-T12730
| 1mg | 75.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 254.00 € | ||
| 25mg | 420.00 € | ||
| 50mg | 592.00 € | ||
| 100mg | 799.00 € | ||
| 1mL*10mM (DMSO) | 148.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
NLRP3-IN-9
CAS:88039-46-7
NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.
Formula:
C12H13ClO3
Purity:
98.51%
Color and Shape:
Solid
Molecular weight:
240.68
Ref: TM-T28178
| 1mg | 41.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 392.00 € | ||
| 100mg | 622.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
RIP1 kinase inhibitor 4
CAS:2919836-00-1
RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 …
Formula:
C23H23N5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
369.46
Ref: TM-T79041
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
