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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 444 products of "NF-κB"

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  • IRAK4-IN-8
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    IRAK4-IN-8

    CAS:
    <p>IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor for the study of diseases associated with cancer and inflammation.</p>
    Formula:C23H23F2N7O2S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:499.54

    Ref: TM-T63388

  • DTP3
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    DTP3

    CAS:
    <p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>
    Formula:C26H35N7O5
    Color and Shape:Solid
    Molecular weight:525.6

    Ref: TM-T22319

  • IRAK inhibitor 2
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    IRAK inhibitor 2

    CAS:
    <p>IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.</p>
    Formula:C17H14N4O2
    Purity:97.90% - 99.58%
    Color and Shape:Solid
    Molecular weight:306.32

    Ref: TM-T7368

  • ML 120B dihydrochloride
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    ML 120B dihydrochloride

    CAS:
    <p>MLN120B dihydrochloride: oral IKKβ inhibitor with 60 nM IC50, suppresses myeloma growth, used in arthritis research.</p>
    Formula:C19H17Cl3N4O2
    Color and Shape:Solid
    Molecular weight:439.72

    Ref: TM-T39199

  • Hesperidin methylchalcone
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    Hesperidin methylchalcone

    CAS:
    <p>Hesperidin methylchalcone, from Citrus, is a potent antioxidant that inhibits NF-κB to alleviate gout arthritis in mice.</p>
    Formula:C29H36O15
    Purity:99.53%
    Color and Shape:Yellow Powder
    Molecular weight:624.59

    Ref: TM-T7980

  • RS 09
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    RS 09

    CAS:
    <p>TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.</p>
    Formula:C31H49N9O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:691.78

    Ref: TM-TP1938

  • Edecesertib
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    Edecesertib

    CAS:
    <p>Edecesertib (GS 5718) is an IRAK-4 inhibitor with anti-inflammatory activity for the study of rheumatoid arthritis.</p>
    Formula:C22H22FN7O2
    Purity:98.84% - 99.94%
    Color and Shape:Solid
    Molecular weight:435.45

    Ref: TM-T62473

  • BIZ 114
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    BIZ 114

    CAS:
    <p>BIZ 114 potently inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and/or treat ophthalmic disorders.</p>
    Formula:C24H40O3
    Color and Shape:Solid
    Molecular weight:376.57

    Ref: TM-T13583

  • TOMATIDINE HYDROCHLORIDE
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    TOMATIDINE HYDROCHLORIDE

    CAS:
    <p>Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.</p>
    Formula:C27H46ClNO2
    Purity:99.75% - ≥95%
    Color and Shape:Solid
    Molecular weight:452.11

    Ref: TM-T4592

  • QNZ
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    QNZ

    CAS:
    <p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>
    Formula:C22H20N4O
    Purity:99.17% - 99.18%
    Color and Shape:White Solid
    Molecular weight:356.42

    Ref: TM-T6204

  • BEC hydrochloride
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    BEC hydrochloride

    CAS:
    <p>BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II.</p>
    Formula:C5H12BNO4S·ClH
    Purity:98.65% - 99.28%
    Color and Shape:Solid
    Molecular weight:229.49

    Ref: TM-T6779

  • Berbamine
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    Berbamine

    CAS:
    <p>Berbamine is a natural product extracted from Phellodendron amurense.</p>
    Formula:C37H40N2O6
    Purity:98.92% - 99.67%
    Color and Shape:White Crystal Powder
    Molecular weight:608.72

    Ref: TM-T3S0807

  • CAFESTOL
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    CAFESTOL

    CAS:
    <p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>
    Formula:C20H28O3
    Purity:97.06% - 99.08%
    Color and Shape:Solid
    Molecular weight:316.43

    Ref: TM-T5727

  • Demethyleneberberine
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    Demethyleneberberine

    CAS:
    <p>Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either</p>
    Formula:C19H18NO4
    Purity:98.08% - 99.18%
    Color and Shape:Solid
    Molecular weight:324.35

    Ref: TM-T4S0800

  • Morusin
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    Morusin

    CAS:
    <p>Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.</p>
    Formula:C25H24O6
    Purity:98.68% - 99.8%
    Color and Shape:Solid
    Molecular weight:420.45

    Ref: TM-T5S1607

  • EUK-134
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    EUK-134

    CAS:
    <p>EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.</p>
    Formula:C18H18ClMnN2O4
    Purity:98.39%
    Color and Shape:Solid
    Molecular weight:416.74

    Ref: TM-T6495

  • Flavanomarein
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    Flavanomarein

    CAS:
    <p>Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.</p>
    Formula:C21H22O11
    Purity:98.63% - 99.54%
    Color and Shape:Solid
    Molecular weight:450.39

    Ref: TM-TN1644

  • Dauricine
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    Dauricine

    CAS:
    <p>1.</p>
    Formula:C38H44N2O6
    Purity:99.24% - 99.75%
    Color and Shape:White Powder
    Molecular weight:624.77

    Ref: TM-T6S0119

  • 3'-Sialyllactose
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    3'-Sialyllactose

    CAS:
    <p>3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.</p>
    Formula:C23H39NO19
    Color and Shape:Solid
    Molecular weight:633.55

    Ref: TM-T72655

  • OPHIOPOGONIN D
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    OPHIOPOGONIN D

    CAS:
    <p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>
    Formula:C44H70O16
    Purity:99.46% - ≥95%
    Color and Shape:Solid
    Molecular weight:855.02

    Ref: TM-T5701