NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Cudraflavone B
CAS:19275-49-1
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in …
Formula:
C25H24O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
420.45
Ref: TM-TN3726
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Thursday 12 Dec 2024
HS-243
CAS:848249-10-5
HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. …
Formula:
C17H16N4O3
Purity:
97.34%
Color and Shape:
Liquid
Molecular weight:
324.33
Ref: TM-T60012
| 1mg | 53.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 377.00 € | ||
| 50mg | 559.00 € | ||
| 100mg | 800.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Edecesertib
CAS:2408839-73-4
Edecesertib (GS 5718) is an IRAK-4 inhibitor with anti-inflammatory activity for the study of rheumatoid …
Formula:
C22H22FN7O2
Purity:
98.84%
Color and Shape:
Liquid
Molecular weight:
435.45
Ref: TM-T62473
| 2mg | 649.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
3'-Sialyllactose sodium
CAS:128596-80-5
3'-Sialyllactose sodium is a prebiotic with anti-inflammatory activity that maintains immune homeostasis and can be …
Formula:
C23H38NNaO19
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
655.53
Ref: TM-T35707
| 5mg | 36.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 90.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Cpd27
CAS:501693-48-7
Cpd27 (TIE-2/VEGFR-2 kinase-IN-2) is a TIE-2 and VEGFR-2 inhibitor that inhibits RIPK1 and can be …
Formula:
C20H13F4N5O2
Color and Shape:
Solid
Molecular weight:
431.34
Ref: TM-T40581
| 1mg | 61.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 208.00 € | ||
| 25mg | 417.00 € | ||
| 50mg | 615.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
NLRP3-IN-11
CAS:2769040-91-5
NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the …
Formula:
C17H17ClN4O2
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
344.8
Ref: TM-T61132
| 5mg | 105.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 249.00 € | ||
| 50mg | 370.00 € | ||
| 100mg | 550.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Hesperidin methylchalcone
CAS:24292-52-2
Hesperidin methylchalcone, from Citrus, is a potent antioxidant that inhibits NF-κB to alleviate gout arthritis …
Formula:
C29H36O15
Color and Shape:
Yellow Powder
Molecular weight:
624.59
Ref: TM-T7980
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 16 Dec 2024
NF-κB/MAPK-IN-1
CAS:2413940-56-2
NF-κB/MAPK-IN-1 is an NF-κB and MAPK pathway inhibitor. NF-κB/MAPK-IN-1 is used to prevent rheumatoid arthritis …
Formula:
C27H27NO7
Purity:
97.03%
Color and Shape:
Liquid
Molecular weight:
477.51
Ref: TM-T63119
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 327.00 € | ||
| 50mg | 485.00 € | ||
| 100mg | 701.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
4-O-Methyl honokiol
CAS:68592-15-4
4-O-Methyl honokiol (4-O-Methylhonokiol), derived from Magnolia officinalis and Magnolia officinalis, is a PPARγ agonist with …
Formula:
C19H20O2
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
280.36
Ref: TM-T10153
| 1mg | 57.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 352.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 753.00 € | ||
| 500mg | 1,557.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
CL075
CAS:256922-53-9
CL075 (3M002) is a selective TLR8 agonist.CL075 has immunomodulatory activity by triggering the MyD88-dependent signaling …
Formula:
C13H13N3S
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
243.33
Ref: TM-T27034
| 1mg | 40.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Muramyl dipeptide
CAS:53678-77-6
MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression …
Formula:
C19H32N4O11
Purity:
100%
Color and Shape:
Solid
Molecular weight:
492.48
Ref: TM-T16159
| 2mg | 190.00 € | ||
| 5mg | 308.00 € | ||
| 10mg | 476.00 € | ||
| 25mg | 818.00 € | ||
| 50mg | 1,163.00 € | ||
| 1mL*10mM (DMSO) | 339.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Fibrinogen
CAS:9001-32-5
Fibrinogen is a heterodimeric protein that can be cleaved by thrombin.
Color and Shape:
Liquid
Ref: TM-T78367
| 100mg | 46.00 € | ||
| 500mg | 87.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
IRAK inhibitor 2
CAS:928333-30-6
IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) …
Formula:
C17H14N4O2
Purity:
97.62% - 99.26%
Color and Shape:
Solid
Molecular weight:
306.32
Ref: TM-T7368
| 1mg | 84.00 € | ||
| 5mg | 176.00 € | ||
| 10mg | 253.00 € | ||
| 25mg | 444.00 € | ||
| 50mg | 639.00 € | ||
| 100mg | 915.00 € | ||
| 500mg | 1,836.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Sappanone A
CAS:102067-84-5
Sappanone A is a high isoflavanone with anti-inflammatory properties.Sappanone A reduces allergic airway inflammation in …
Formula:
C16H12O5
Purity:
97.48%
Color and Shape:
Solid
Molecular weight:
284.26
Ref: TM-TMA1570
| 5mg | 60.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 408.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
DTP3
CAS:1809784-29-9
DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.
Formula:
C26H35N7O5
Color and Shape:
Solid
Molecular weight:
525.6
Ref: TM-T22319
| 2mg | 82.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 214.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
IRAK4-IN-10
CAS:2681278-09-9
IRAK4-IN-10, a potent IRAK4 blocker with IC50 of 1.5 nM, may treat inflammation, autoimmunity, and …
Formula:
C22H24N8
Purity:
99.76%
Color and Shape:
Liquid
Molecular weight:
400.48
Ref: TM-T61931
| 1mg | 598.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
IRAK4-IN-8
CAS:2033070-97-0
IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor for the study of diseases associated with cancer and …
Formula:
C23H23F2N7O2S
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
499.54
Ref: TM-T63388
| 1mg | 808.00 € | ||
| 2mg | 1,108.00 € | ||
| 5mg | 1,647.00 € | ||
| 10mg | 2,224.00 € | ||
| 25mg | 3,303.00 € | ||
| 50mg | 4,448.00 € | ||
| 100mg | 6,020.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
GSK-843
CAS:1601496-05-2
GSK-843 (GSK'843) is a RIP3 inhibitor with analgesic activity, inhibits RIP3 expression, and can be …
Formula:
C19H15N5S2
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
377.49
Ref: TM-T11474
| 1mg | 143.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
GSK-872
CAS:1346546-69-7
GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain …
Formula:
C19H17N3O2S2
Purity:
99.3%
Color and Shape:
Solid
Molecular weight:
383.49
Ref: TM-T4074
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 517.00 € | ||
| 500mg | 1,140.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Sinomenine
CAS:115-53-7
Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the …
Formula:
C19H23NO4
Purity:
99.02% - 99.89%
Color and Shape:
White Powder
Molecular weight:
329.39
Ref: TM-T2726
| 100mg | 59.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
