CymitQuimica logo
NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 444 products of "NF-κB"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • 7-O-Methylaloeasinol
    Targetmol
    + Info

    7-O-Methylaloeasinol

    CAS:
    <p>7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.</p>
    Formula:C20H26O9
    Color and Shape:Solid
    Molecular weight:410.419

    Ref: TM-T126468

  • Nasunin
    Targetmol
    + Info

    Nasunin

    CAS:
    <p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>
    Formula:C42H47ClO23
    Color and Shape:Solid
    Molecular weight:955.26

    Ref: TM-T31371

  • Siegesbeckialide I
    Targetmol
    + Info

    Siegesbeckialide I

    <p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>
    Formula:C20H28O6
    Color and Shape:Solid
    Molecular weight:364.43

    Ref: TM-T72578

  • NF-κB Signaling Compound Library
    Targetmol
    + Info

    NF-κB Signaling Compound Library

    <p>A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;</p>
    Color and Shape:Odour Solid

    Ref: TM-L3800

  • Mesalamine impurity P
    Targetmol
    + Info

    Mesalamine impurity P

    CAS:
    <p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>
    Formula:C13H11NO6S
    Color and Shape:Solid
    Molecular weight:309.30

    Ref: TM-T37026

  • NF-κΒ activator 1
    Targetmol
    + Info

    NF-κΒ activator 1

    CAS:
    <p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>
    Formula:C16H11FN2O2S
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:314.33

    Ref: TM-T39965

  • CAY10657
    Targetmol
    + Info

    CAY10657

    CAS:
    <p>CAY10657 has a wide range of applications in life science related research.</p>
    Formula:C17H20N4O3S
    Color and Shape:Solid
    Molecular weight:360.43

    Ref: TM-T38368

  • CymitQuimica logo
    Targetmol
    + Info

    PROTAC STING degrader-3

    <p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206857

  • CymitQuimica logo
    Targetmol
    + Info

    3-(2-Hydroxyethyl) thio withaferin A

    <p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>
    Formula:C30H44O7S
    Color and Shape:Solid
    Molecular weight:548.73

    Ref: TM-T75491

  • Licoagrochalcone C
    Targetmol
    + Info

    Licoagrochalcone C

    CAS:
    <p>Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.</p>
    Formula:C21H22O5
    Color and Shape:Solid
    Molecular weight:354.4

    Ref: TM-T74203

  • TBK1/IKKε-IN-6
    Targetmol
    + Info

    TBK1/IKKε-IN-6

    CAS:
    <p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>
    Formula:C31H36F2N8O4
    Color and Shape:Solid
    Molecular weight:622.678

    Ref: TM-T39841

  • Helenalin
    Targetmol
    + Info

    Helenalin

    CAS:
    <p>Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.</p>
    Formula:C15H18O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:262.3

    Ref: TM-T15467

  • HS-243
    Targetmol
    + Info

    HS-243

    CAS:
    <p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>
    Formula:C17H16N4O3
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:324.33

    Ref: TM-T60012

  • CymitQuimica logo
    Targetmol
    + Info

    R-HP210

    <p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>
    Formula:C22H19N3O2S2
    Color and Shape:Solid
    Molecular weight:421.54

    Ref: TM-T62252

  • CymitQuimica logo
    Targetmol
    + Info

    Anti-osteoporosis agent-4

    <p>Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis.</p>
    Formula:C26H26ClN3O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:560.02

    Ref: TM-T78816

  • CymitQuimica logo
    Targetmol
    + Info

    Narlumosbart

    CAS:
    <p>Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].</p>
    Purity:98%
    Color and Shape:Liquid

    Ref: TM-T80618

  • 12-Oxo phytodienoic acid
    Targetmol
    + Info

    12-Oxo phytodienoic acid

    CAS:
    <p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>
    Formula:C18H28O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:292.41

    Ref: TM-T33808

  • OT-551 HCl
    Targetmol
    + Info

    OT-551 HCl

    CAS:
    <p>OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular</p>
    Formula:C13H24ClNO3
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:277.79

    Ref: TM-T28273L

  • Murrayafoline A
    Targetmol
    + Info

    Murrayafoline A

    CAS:
    <p>Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.</p>
    Formula:C14H13NO
    Color and Shape:Solid
    Molecular weight:211.264

    Ref: TM-T124835

  • DTP3
    Targetmol
    + Info

    DTP3

    CAS:
    <p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>
    Formula:C26H35N7O5
    Color and Shape:Solid
    Molecular weight:525.6

    Ref: TM-T22319