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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 444 products of "NF-κB"

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  • Cyclo(his-pro)
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    Cyclo(his-pro)

    CAS:
    <p>Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.</p>
    Formula:C11H14N4O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:234.25

    Ref: TM-T7511

  • MD2-TLR4-IN-1
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    MD2-TLR4-IN-1

    CAS:
    <p>MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.</p>
    Formula:C22H14Cl2N4O
    Purity:97.74%
    Color and Shape:Solid
    Molecular weight:421.28

    Ref: TM-T7672

  • ETHYL CAFFEATE
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    ETHYL CAFFEATE

    CAS:
    <p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>
    Formula:C11H12O4
    Purity:97.79%
    Color and Shape:Solid
    Molecular weight:208.21

    Ref: TM-T5681

  • CymitQuimica logo
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    Denosumab

    CAS:
    <p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>
    Formula:C6404H9912N1724O2004S50
    Purity:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%
    Color and Shape:Liquid
    Molecular weight:144.71 kDa

    Ref: TM-T9917

  • GSK8612
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    GSK8612

    CAS:
    <p>GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .</p>
    Formula:C17H17BrF3N7O2S
    Purity:99.46% - 99.8%
    Color and Shape:Solid
    Molecular weight:520.33

    Ref: TM-T5540

  • Tizoxanide
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    Tizoxanide

    CAS:
    Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.
    Formula:C10H7N3O4S
    Purity:98.89% - 99.28%
    Color and Shape:Solid
    Molecular weight:265.25

    Ref: TM-T2279

  • Avicularin
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    Avicularin

    CAS:
    <p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>
    Formula:C20H18O11
    Purity:97.02% - 99.94%
    Color and Shape:White Powder
    Molecular weight:434.35

    Ref: TM-T6S0117

  • Ginsenoside Rb3
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    Ginsenoside Rb3

    CAS:
    <p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>
    Formula:C53H90O22
    Purity:98% - 99.98%
    Color and Shape:Solid
    Molecular weight:1079.27

    Ref: TM-T3918

  • MLN120B
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    MLN120B

    CAS:
    <p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>
    Formula:C19H15ClN4O2
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:366.8

    Ref: TM-TQ0306

  • Eclitasertib
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    Eclitasertib

    CAS:
    <p>Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of &lt;1 µΜ).</p>
    Formula:C19H18N6O3
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:378.38

    Ref: TM-T9702

  • Berbamine
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    Berbamine

    CAS:
    <p>Berbamine is a natural product extracted from Phellodendron amurense.</p>
    Formula:C37H40N2O6
    Purity:98.92% - 99.67%
    Color and Shape:White Crystal Powder
    Molecular weight:608.72

    Ref: TM-T3S0807

  • Isoquercetin
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    Isoquercetin

    CAS:
    <p>1.</p>
    Formula:C21H20O12
    Purity:98.08% - 99.76%
    Color and Shape:Solid
    Molecular weight:464.38

    Ref: TM-T5S0754

  • WITHAFERIN A
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    WITHAFERIN A

    CAS:
    <p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>
    Formula:C28H38O6
    Purity:97.41% - 99.99%
    Color and Shape:Solid
    Molecular weight:470.6

    Ref: TM-T5687

  • Ginsenoside Rd
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    Ginsenoside Rd

    CAS:
    <p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>
    Formula:C48H82O18
    Purity:99.13% - 99.92%
    Color and Shape:Solid
    Molecular weight:947.15

    Ref: TM-T2878

  • Dehydroevodiamine
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    Dehydroevodiamine

    CAS:
    <p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>
    Formula:C19H15N3O
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:301.34

    Ref: TM-T2S2335

  • IRAK inhibitor 6
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    IRAK inhibitor 6

    CAS:
    <p>IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).</p>
    Formula:C20H20N4O3S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46

    Ref: TM-T5110

  • 2-Hydroxychalcone
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    2-Hydroxychalcone

    CAS:
    <p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>
    Formula:C15H12O2
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:224.25

    Ref: TM-T7979

  • 2,5-Dihydroxyacetophenone
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    2,5-Dihydroxyacetophenone

    CAS:
    <p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>
    Formula:C8H8O3
    Purity:99.75%
    Color and Shape:Yellow Powder
    Molecular weight:152.15

    Ref: TM-TCS2170

  • Muscone
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    Muscone

    CAS:
    <p>Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.</p>
    Formula:C16H30O
    Purity:98.97% - ≥98%
    Color and Shape:Colourless Liquid Liquid
    Molecular weight:238.41

    Ref: TM-T2893

  • Phellodendrine
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    Phellodendrine

    CAS:
    <p>Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.</p>
    Formula:C20H24NO4
    Purity:98.7% - 99.94%
    Color and Shape:Solid
    Molecular weight:342.41

    Ref: TM-T6S0781